Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years

Autores
Diaz, Alberto Alejandro; Zocalo, Yanina; Bia, Daniel; Wray, Sandra; Cabrera Fischer, Edmundo Ignacio
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
There is little information regarding age-related reference intervals (RIs) of carotidfemoral pulse wave velocity (cfPWV) for large healthy populations in South America. The aims of this study were to determine cfPWV RIs and percentiles in a cohort of healthy children, adolescents, and adults and to generate year-to-year percentile curves and body-height percentile curves for children and adolescents. cfPWV was measured in 1722 healthy participants with no cardiovascular risk factors (9–87 years, 60% men). First, RIs were evaluated for males and females through correlation and covariate analysis. Then, mean and standard deviation age-related equations were obtained for cfPWV using parametric regression methods based on fractional polynomials and age-specific (year-to-year) percentile curves that were defined using the standard normal distribution. Age-specific first, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th, and 99th percentile curves were calculated. Finally, height-related cfPWV percentile curves for children and adolescents (<21 years) were established. After adjusting for age and blood pressure differences with respect to females, males showed higher cfPWV levels (6.60 vs 6.45 m/s; P < .01). Thus, specific RIs for males and females were reported. The study provides the largest database to date concerning cfPWV in healthy people from Argentina. Specific RIs and percentiles of cfPWV are now available according to age and sex. Specific percentiles of cfPWV according to body height were reported for people younger than 21 years.
Fil: Diaz, Alberto Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Escuela Superior de Ciencias de la Salud. Instituto de Investigación en Ciencias de la Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina
Fil: Zocalo, Yanina. Universidad de la Republica. Facultad de Medicina; Uruguay
Fil: Bia, Daniel. Universidad de la Republica. Facultad de Medicina; Uruguay
Fil: Wray, Sandra. Universidad Favaloro; Argentina
Fil: Cabrera Fischer, Edmundo Ignacio. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
PULSE WAVE VELOCITY
EPIDEMIOLOGIA
ARGENTINA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/112240

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spelling Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 yearsDiaz, Alberto AlejandroZocalo, YaninaBia, DanielWray, SandraCabrera Fischer, Edmundo IgnacioPULSE WAVE VELOCITYEPIDEMIOLOGIAARGENTINAhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3There is little information regarding age-related reference intervals (RIs) of carotidfemoral pulse wave velocity (cfPWV) for large healthy populations in South America. The aims of this study were to determine cfPWV RIs and percentiles in a cohort of healthy children, adolescents, and adults and to generate year-to-year percentile curves and body-height percentile curves for children and adolescents. cfPWV was measured in 1722 healthy participants with no cardiovascular risk factors (9–87 years, 60% men). First, RIs were evaluated for males and females through correlation and covariate analysis. Then, mean and standard deviation age-related equations were obtained for cfPWV using parametric regression methods based on fractional polynomials and age-specific (year-to-year) percentile curves that were defined using the standard normal distribution. Age-specific first, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th, and 99th percentile curves were calculated. Finally, height-related cfPWV percentile curves for children and adolescents (<21 years) were established. After adjusting for age and blood pressure differences with respect to females, males showed higher cfPWV levels (6.60 vs 6.45 m/s; P < .01). Thus, specific RIs for males and females were reported. The study provides the largest database to date concerning cfPWV in healthy people from Argentina. Specific RIs and percentiles of cfPWV are now available according to age and sex. Specific percentiles of cfPWV according to body height were reported for people younger than 21 years.Fil: Diaz, Alberto Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Escuela Superior de Ciencias de la Salud. Instituto de Investigación en Ciencias de la Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; ArgentinaFil: Zocalo, Yanina. Universidad de la Republica. Facultad de Medicina; UruguayFil: Bia, Daniel. Universidad de la Republica. Facultad de Medicina; UruguayFil: Wray, Sandra. Universidad Favaloro; ArgentinaFil: Cabrera Fischer, Edmundo Ignacio. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaWiley Blackwell Publishing, Inc2018-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/112240Diaz, Alberto Alejandro; Zocalo, Yanina; Bia, Daniel; Wray, Sandra; Cabrera Fischer, Edmundo Ignacio; Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years; Wiley Blackwell Publishing, Inc; Journal Of Clinical Hypertension; 3-2018; 1-131524-6175CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/jch.13251info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/jch.13251info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:09:31Zoai:ri.conicet.gov.ar:11336/112240instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:09:32.02CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
title Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
spellingShingle Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
Diaz, Alberto Alejandro
PULSE WAVE VELOCITY
EPIDEMIOLOGIA
ARGENTINA
title_short Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
title_full Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
title_fullStr Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
title_full_unstemmed Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
title_sort Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years
dc.creator.none.fl_str_mv Diaz, Alberto Alejandro
Zocalo, Yanina
Bia, Daniel
Wray, Sandra
Cabrera Fischer, Edmundo Ignacio
author Diaz, Alberto Alejandro
author_facet Diaz, Alberto Alejandro
Zocalo, Yanina
Bia, Daniel
Wray, Sandra
Cabrera Fischer, Edmundo Ignacio
author_role author
author2 Zocalo, Yanina
Bia, Daniel
Wray, Sandra
Cabrera Fischer, Edmundo Ignacio
author2_role author
author
author
author
dc.subject.none.fl_str_mv PULSE WAVE VELOCITY
EPIDEMIOLOGIA
ARGENTINA
topic PULSE WAVE VELOCITY
EPIDEMIOLOGIA
ARGENTINA
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv There is little information regarding age-related reference intervals (RIs) of carotidfemoral pulse wave velocity (cfPWV) for large healthy populations in South America. The aims of this study were to determine cfPWV RIs and percentiles in a cohort of healthy children, adolescents, and adults and to generate year-to-year percentile curves and body-height percentile curves for children and adolescents. cfPWV was measured in 1722 healthy participants with no cardiovascular risk factors (9–87 years, 60% men). First, RIs were evaluated for males and females through correlation and covariate analysis. Then, mean and standard deviation age-related equations were obtained for cfPWV using parametric regression methods based on fractional polynomials and age-specific (year-to-year) percentile curves that were defined using the standard normal distribution. Age-specific first, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th, and 99th percentile curves were calculated. Finally, height-related cfPWV percentile curves for children and adolescents (<21 years) were established. After adjusting for age and blood pressure differences with respect to females, males showed higher cfPWV levels (6.60 vs 6.45 m/s; P < .01). Thus, specific RIs for males and females were reported. The study provides the largest database to date concerning cfPWV in healthy people from Argentina. Specific RIs and percentiles of cfPWV are now available according to age and sex. Specific percentiles of cfPWV according to body height were reported for people younger than 21 years.
Fil: Diaz, Alberto Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Escuela Superior de Ciencias de la Salud. Instituto de Investigación en Ciencias de la Salud; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil; Argentina
Fil: Zocalo, Yanina. Universidad de la Republica. Facultad de Medicina; Uruguay
Fil: Bia, Daniel. Universidad de la Republica. Facultad de Medicina; Uruguay
Fil: Wray, Sandra. Universidad Favaloro; Argentina
Fil: Cabrera Fischer, Edmundo Ignacio. Universidad Favaloro; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description There is little information regarding age-related reference intervals (RIs) of carotidfemoral pulse wave velocity (cfPWV) for large healthy populations in South America. The aims of this study were to determine cfPWV RIs and percentiles in a cohort of healthy children, adolescents, and adults and to generate year-to-year percentile curves and body-height percentile curves for children and adolescents. cfPWV was measured in 1722 healthy participants with no cardiovascular risk factors (9–87 years, 60% men). First, RIs were evaluated for males and females through correlation and covariate analysis. Then, mean and standard deviation age-related equations were obtained for cfPWV using parametric regression methods based on fractional polynomials and age-specific (year-to-year) percentile curves that were defined using the standard normal distribution. Age-specific first, 2.5th, 5th, 10th, 25th, 50th, 75th, 90th, 95th, 97.5th, and 99th percentile curves were calculated. Finally, height-related cfPWV percentile curves for children and adolescents (<21 years) were established. After adjusting for age and blood pressure differences with respect to females, males showed higher cfPWV levels (6.60 vs 6.45 m/s; P < .01). Thus, specific RIs for males and females were reported. The study provides the largest database to date concerning cfPWV in healthy people from Argentina. Specific RIs and percentiles of cfPWV are now available according to age and sex. Specific percentiles of cfPWV according to body height were reported for people younger than 21 years.
publishDate 2018
dc.date.none.fl_str_mv 2018-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/112240
Diaz, Alberto Alejandro; Zocalo, Yanina; Bia, Daniel; Wray, Sandra; Cabrera Fischer, Edmundo Ignacio; Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years; Wiley Blackwell Publishing, Inc; Journal Of Clinical Hypertension; 3-2018; 1-13
1524-6175
CONICET Digital
CONICET
url http://hdl.handle.net/11336/112240
identifier_str_mv Diaz, Alberto Alejandro; Zocalo, Yanina; Bia, Daniel; Wray, Sandra; Cabrera Fischer, Edmundo Ignacio; Reference intervals and percentiles for carotid-femoral pulse wave velocity in a healthy population aged between 9 and 87 years; Wiley Blackwell Publishing, Inc; Journal Of Clinical Hypertension; 3-2018; 1-13
1524-6175
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/jch.13251
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/jch.13251
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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