Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel
- Autores
- Jofre, Claudio Francisco; Bonilla, José Oscar; Molina, Luciana Vanina; Campos, Ludmila Estefanía; Mastrodonato, Anna Chiara; Icazatti, Alejandro; Quijano, Federico; Esteves, B.; Aguilera, Leonardo; Carrizo, Erica; Sanchez, Laura; Perez Diaz, Matías; Rosales, Eliana; Cabral,Florencia; Peñalva, Julieta; Guevara, Alicia; Olivera, Marcelo; Rivero, Gustavo; Bohn, Jorge; Lacaze, Maria Agustina; Talia, Juan Manuel
- Año de publicación
- 2021
- Idioma
- inglés
- Tipo de recurso
- documento de conferencia
- Estado
- versión publicada
- Descripción
- The occurrence of mutations is a natural and expected event within the evolutionary process of viruses. The massive spread of the SARS-CoV-2 led to the accumulation of mutations within the viral genome, generating new variants. The capacity to monitor the data in real time impacts directly on the COVID-19 pandemic public health response. The knowledge of the community circulation of Variants Of Concern (VOCs), such as , , and , or Variants Of Interest (VOIs), as and , requires sampling and sequencing strategies to ensure representativeness and reliability of the results. In San Luis, the PLSP has access to COVID-19 positive samples and works closely with the Programa de Epidemiología. Our health institution applied two different surveillance strategies to detect the SARS-CoV-2 variants. The first strategy consisted of whole or partial genome sequencing, which were carried out at ANLIS-Malbrán and PAIS Project. On the other hand, a PCR screening strategy was developed by researchers from the UNSL and implemented for the early detection of the VOC. A total of 169 positive samples were analyzed applying the first strategy among epidemiological weeks (EW) 14 to 36 in 2021. 113 samples were selected by regular sampling, taking into account high transmission areas, different age ranges, geographic location and severity. Additionally, 38 immunized people, 7 samples suspected of reinfection and 7 travelers were analyzed. The main variants found were: (43%), (11%), (5%), (1%), and other Not VOC/VOI (27%). Interestingly, since EW 19, the proportion of cases associated with VOC and VOI increased while those associated with VOC decreased. The second strategy was applied on 1367 samples from EW 25 to 40 and VOC was not detected as a circulant variant in San Luis. In this work we show genomic evidence of local transmission of SARS-CoV-2 VOC , and . The variant was only found in one traveler who returned from Colombia. It should be noted that, according to the results obtained in this work, the VOC and VOI are the main circulating variants in the province, while VOC is not detected nowadays. The results were opportunely communicated to the authorities to be used for the benefit of public health.
Fil: Jofre, Claudio Francisco. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Bonilla, José Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud San Luis; Argentina
Fil: Molina, Luciana Vanina. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Campos, Ludmila Estefanía. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mastrodonato, Anna Chiara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud San Luis; Argentina
Fil: Icazatti, Alejandro. Ministerio de Salud San Luis; Argentina
Fil: Quijano, Federico. Ministerio de Salud San Luis; Argentina
Fil: Esteves, B.. Ministerio de Salud San Luis; Argentina
Fil: Aguilera, Leonardo. Ministerio de Salud San Luis; Argentina
Fil: Carrizo, Erica. Ministerio de Salud San Luis; Argentina
Fil: Sanchez, Laura. Ministerio de Salud San Luis; Argentina
Fil: Perez Diaz, Matías. Ministerio de Salud San Luis; Argentina
Fil: Rosales, Eliana. Ministerio de Salud San Luis; Argentina
Fil: Cabral,Florencia. Ministerio de Salud San Luis; Argentina
Fil: Peñalva, Julieta. Ministerio de Salud San Luis; Argentina
Fil: Guevara, Alicia. Ministerio de Salud San Luis; Argentina
Fil: Olivera, Marcelo. Ministerio de Salud San Luis; Argentina
Fil: Rivero, Gustavo. Ministerio de Salud San Luis; Argentina
Fil: Bohn, Jorge. Ministerio de Salud San Luis; Argentina
Fil: Lacaze, Maria Agustina. Ministerio de Salud San Luis; Argentina
Fil: Talia, Juan Manuel. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
XXXIX Reunión Científica Anual de la Sociedad de Biología de Cuyo
San Luis
Argentina
Sociedad de Biología de Cuyo - Materia
-
KINETICS
ANTIBODIES
SPUTNIK V
VACCINATION - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/281993
Ver los metadatos del registro completo
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Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnelJofre, Claudio FranciscoBonilla, José OscarMolina, Luciana VaninaCampos, Ludmila EstefaníaMastrodonato, Anna ChiaraIcazatti, AlejandroQuijano, FedericoEsteves, B.Aguilera, LeonardoCarrizo, EricaSanchez, LauraPerez Diaz, MatíasRosales, ElianaCabral,FlorenciaPeñalva, JulietaGuevara, AliciaOlivera, MarceloRivero, GustavoBohn, JorgeLacaze, Maria AgustinaTalia, Juan ManuelKINETICSANTIBODIESSPUTNIK VVACCINATIONhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The occurrence of mutations is a natural and expected event within the evolutionary process of viruses. The massive spread of the SARS-CoV-2 led to the accumulation of mutations within the viral genome, generating new variants. The capacity to monitor the data in real time impacts directly on the COVID-19 pandemic public health response. The knowledge of the community circulation of Variants Of Concern (VOCs), such as , , and , or Variants Of Interest (VOIs), as and , requires sampling and sequencing strategies to ensure representativeness and reliability of the results. In San Luis, the PLSP has access to COVID-19 positive samples and works closely with the Programa de Epidemiología. Our health institution applied two different surveillance strategies to detect the SARS-CoV-2 variants. The first strategy consisted of whole or partial genome sequencing, which were carried out at ANLIS-Malbrán and PAIS Project. On the other hand, a PCR screening strategy was developed by researchers from the UNSL and implemented for the early detection of the VOC. A total of 169 positive samples were analyzed applying the first strategy among epidemiological weeks (EW) 14 to 36 in 2021. 113 samples were selected by regular sampling, taking into account high transmission areas, different age ranges, geographic location and severity. Additionally, 38 immunized people, 7 samples suspected of reinfection and 7 travelers were analyzed. The main variants found were: (43%), (11%), (5%), (1%), and other Not VOC/VOI (27%). Interestingly, since EW 19, the proportion of cases associated with VOC and VOI increased while those associated with VOC decreased. The second strategy was applied on 1367 samples from EW 25 to 40 and VOC was not detected as a circulant variant in San Luis. In this work we show genomic evidence of local transmission of SARS-CoV-2 VOC , and . The variant was only found in one traveler who returned from Colombia. It should be noted that, according to the results obtained in this work, the VOC and VOI are the main circulating variants in the province, while VOC is not detected nowadays. The results were opportunely communicated to the authorities to be used for the benefit of public health.Fil: Jofre, Claudio Francisco. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bonilla, José Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud San Luis; ArgentinaFil: Molina, Luciana Vanina. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Campos, Ludmila Estefanía. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mastrodonato, Anna Chiara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud San Luis; ArgentinaFil: Icazatti, Alejandro. Ministerio de Salud San Luis; ArgentinaFil: Quijano, Federico. Ministerio de Salud San Luis; ArgentinaFil: Esteves, B.. Ministerio de Salud San Luis; ArgentinaFil: Aguilera, Leonardo. Ministerio de Salud San Luis; ArgentinaFil: Carrizo, Erica. Ministerio de Salud San Luis; ArgentinaFil: Sanchez, Laura. Ministerio de Salud San Luis; ArgentinaFil: Perez Diaz, Matías. Ministerio de Salud San Luis; ArgentinaFil: Rosales, Eliana. Ministerio de Salud San Luis; ArgentinaFil: Cabral,Florencia. Ministerio de Salud San Luis; ArgentinaFil: Peñalva, Julieta. Ministerio de Salud San Luis; ArgentinaFil: Guevara, Alicia. Ministerio de Salud San Luis; ArgentinaFil: Olivera, Marcelo. Ministerio de Salud San Luis; ArgentinaFil: Rivero, Gustavo. Ministerio de Salud San Luis; ArgentinaFil: Bohn, Jorge. Ministerio de Salud San Luis; ArgentinaFil: Lacaze, Maria Agustina. Ministerio de Salud San Luis; ArgentinaFil: Talia, Juan Manuel. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaXXXIX Reunión Científica Anual de la Sociedad de Biología de CuyoSan LuisArgentinaSociedad de Biología de CuyoSociedad Biologia de Cuyo2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectCongresoBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/281993Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel; XXXIX Reunión Científica Anual de la Sociedad de Biología de Cuyo; San Luis; Argentina; 2021; 36-370327-9545CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://sbcuyo.org.ar/reuniones-anuales-anteriores/Nacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-03-11T12:56:07Zoai:ri.conicet.gov.ar:11336/281993instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-03-11 12:56:08.164CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| title |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| spellingShingle |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel Jofre, Claudio Francisco KINETICS ANTIBODIES SPUTNIK V VACCINATION |
| title_short |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| title_full |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| title_fullStr |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| title_full_unstemmed |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| title_sort |
Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel |
| dc.creator.none.fl_str_mv |
Jofre, Claudio Francisco Bonilla, José Oscar Molina, Luciana Vanina Campos, Ludmila Estefanía Mastrodonato, Anna Chiara Icazatti, Alejandro Quijano, Federico Esteves, B. Aguilera, Leonardo Carrizo, Erica Sanchez, Laura Perez Diaz, Matías Rosales, Eliana Cabral,Florencia Peñalva, Julieta Guevara, Alicia Olivera, Marcelo Rivero, Gustavo Bohn, Jorge Lacaze, Maria Agustina Talia, Juan Manuel |
| author |
Jofre, Claudio Francisco |
| author_facet |
Jofre, Claudio Francisco Bonilla, José Oscar Molina, Luciana Vanina Campos, Ludmila Estefanía Mastrodonato, Anna Chiara Icazatti, Alejandro Quijano, Federico Esteves, B. Aguilera, Leonardo Carrizo, Erica Sanchez, Laura Perez Diaz, Matías Rosales, Eliana Cabral,Florencia Peñalva, Julieta Guevara, Alicia Olivera, Marcelo Rivero, Gustavo Bohn, Jorge Lacaze, Maria Agustina Talia, Juan Manuel |
| author_role |
author |
| author2 |
Bonilla, José Oscar Molina, Luciana Vanina Campos, Ludmila Estefanía Mastrodonato, Anna Chiara Icazatti, Alejandro Quijano, Federico Esteves, B. Aguilera, Leonardo Carrizo, Erica Sanchez, Laura Perez Diaz, Matías Rosales, Eliana Cabral,Florencia Peñalva, Julieta Guevara, Alicia Olivera, Marcelo Rivero, Gustavo Bohn, Jorge Lacaze, Maria Agustina Talia, Juan Manuel |
| author2_role |
author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
KINETICS ANTIBODIES SPUTNIK V VACCINATION |
| topic |
KINETICS ANTIBODIES SPUTNIK V VACCINATION |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| dc.description.none.fl_txt_mv |
The occurrence of mutations is a natural and expected event within the evolutionary process of viruses. The massive spread of the SARS-CoV-2 led to the accumulation of mutations within the viral genome, generating new variants. The capacity to monitor the data in real time impacts directly on the COVID-19 pandemic public health response. The knowledge of the community circulation of Variants Of Concern (VOCs), such as , , and , or Variants Of Interest (VOIs), as and , requires sampling and sequencing strategies to ensure representativeness and reliability of the results. In San Luis, the PLSP has access to COVID-19 positive samples and works closely with the Programa de Epidemiología. Our health institution applied two different surveillance strategies to detect the SARS-CoV-2 variants. The first strategy consisted of whole or partial genome sequencing, which were carried out at ANLIS-Malbrán and PAIS Project. On the other hand, a PCR screening strategy was developed by researchers from the UNSL and implemented for the early detection of the VOC. A total of 169 positive samples were analyzed applying the first strategy among epidemiological weeks (EW) 14 to 36 in 2021. 113 samples were selected by regular sampling, taking into account high transmission areas, different age ranges, geographic location and severity. Additionally, 38 immunized people, 7 samples suspected of reinfection and 7 travelers were analyzed. The main variants found were: (43%), (11%), (5%), (1%), and other Not VOC/VOI (27%). Interestingly, since EW 19, the proportion of cases associated with VOC and VOI increased while those associated with VOC decreased. The second strategy was applied on 1367 samples from EW 25 to 40 and VOC was not detected as a circulant variant in San Luis. In this work we show genomic evidence of local transmission of SARS-CoV-2 VOC , and . The variant was only found in one traveler who returned from Colombia. It should be noted that, according to the results obtained in this work, the VOC and VOI are the main circulating variants in the province, while VOC is not detected nowadays. The results were opportunely communicated to the authorities to be used for the benefit of public health. Fil: Jofre, Claudio Francisco. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Bonilla, José Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud San Luis; Argentina Fil: Molina, Luciana Vanina. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Campos, Ludmila Estefanía. Ministerio de Salud San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Mastrodonato, Anna Chiara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Salud San Luis; Argentina Fil: Icazatti, Alejandro. Ministerio de Salud San Luis; Argentina Fil: Quijano, Federico. Ministerio de Salud San Luis; Argentina Fil: Esteves, B.. Ministerio de Salud San Luis; Argentina Fil: Aguilera, Leonardo. Ministerio de Salud San Luis; Argentina Fil: Carrizo, Erica. Ministerio de Salud San Luis; Argentina Fil: Sanchez, Laura. Ministerio de Salud San Luis; Argentina Fil: Perez Diaz, Matías. Ministerio de Salud San Luis; Argentina Fil: Rosales, Eliana. Ministerio de Salud San Luis; Argentina Fil: Cabral,Florencia. Ministerio de Salud San Luis; Argentina Fil: Peñalva, Julieta. Ministerio de Salud San Luis; Argentina Fil: Guevara, Alicia. Ministerio de Salud San Luis; Argentina Fil: Olivera, Marcelo. Ministerio de Salud San Luis; Argentina Fil: Rivero, Gustavo. Ministerio de Salud San Luis; Argentina Fil: Bohn, Jorge. Ministerio de Salud San Luis; Argentina Fil: Lacaze, Maria Agustina. Ministerio de Salud San Luis; Argentina Fil: Talia, Juan Manuel. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina XXXIX Reunión Científica Anual de la Sociedad de Biología de Cuyo San Luis Argentina Sociedad de Biología de Cuyo |
| description |
The occurrence of mutations is a natural and expected event within the evolutionary process of viruses. The massive spread of the SARS-CoV-2 led to the accumulation of mutations within the viral genome, generating new variants. The capacity to monitor the data in real time impacts directly on the COVID-19 pandemic public health response. The knowledge of the community circulation of Variants Of Concern (VOCs), such as , , and , or Variants Of Interest (VOIs), as and , requires sampling and sequencing strategies to ensure representativeness and reliability of the results. In San Luis, the PLSP has access to COVID-19 positive samples and works closely with the Programa de Epidemiología. Our health institution applied two different surveillance strategies to detect the SARS-CoV-2 variants. The first strategy consisted of whole or partial genome sequencing, which were carried out at ANLIS-Malbrán and PAIS Project. On the other hand, a PCR screening strategy was developed by researchers from the UNSL and implemented for the early detection of the VOC. A total of 169 positive samples were analyzed applying the first strategy among epidemiological weeks (EW) 14 to 36 in 2021. 113 samples were selected by regular sampling, taking into account high transmission areas, different age ranges, geographic location and severity. Additionally, 38 immunized people, 7 samples suspected of reinfection and 7 travelers were analyzed. The main variants found were: (43%), (11%), (5%), (1%), and other Not VOC/VOI (27%). Interestingly, since EW 19, the proportion of cases associated with VOC and VOI increased while those associated with VOC decreased. The second strategy was applied on 1367 samples from EW 25 to 40 and VOC was not detected as a circulant variant in San Luis. In this work we show genomic evidence of local transmission of SARS-CoV-2 VOC , and . The variant was only found in one traveler who returned from Colombia. It should be noted that, according to the results obtained in this work, the VOC and VOI are the main circulating variants in the province, while VOC is not detected nowadays. The results were opportunely communicated to the authorities to be used for the benefit of public health. |
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Kinetics of Anti-Spike SARS-CoV-2 antibodies post Sputnik V homologous-scheme vaccination in health personnel; XXXIX Reunión Científica Anual de la Sociedad de Biología de Cuyo; San Luis; Argentina; 2021; 36-37 0327-9545 CONICET Digital CONICET |
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