Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions

Autores
Champion, Christophe; Galassi, Mariel Elisa; Lekadir, Hacène; Incerti, Sébastien; Fojon, Omar Ariel; Rivarola, Roberto Daniel; Hanssen, Jocelyn
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Although DNA lesions are considered of prime importance for describing the post-irradiation cellular survival, they still remain rarely studied on both experimental and theoretical sides. Under these conditions, we here propose different theoretical models for predicting the single ionization and single capture total cross sections for DNA bases impacted by protons.Material and methods: Three theoretical approaches are developed: a first classical one based on a classical trajectory Monte Carlo (CTMC) model and two quantum mechanical ones, namely, a Coulomb Born (CB1) and a continuum-distorted wave eikonal-initial-state (CDW-EIS) model. Results: Ionization and capture processes induced by protons on DNA bases (adenine, cytosine, thymine and guanine) are here studied in terms of total cross sections. Conclusions: A very good agreement is obtained between the different models at high enough impact velocities but discrepancies are observed between them at low impact energies (Ei<100 keV). Furthermore, it is shown that the theoretical cross sections underestimate the rare existing experimental data in particular for adenine and thymine whereas a reasonable agreement is found for cytosine.
Fil: Champion, Christophe. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; Francia
Fil: Galassi, Mariel Elisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina
Fil: Lekadir, Hacène. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; Francia
Fil: Incerti, Sébastien. Universite de Bordeaux; Francia
Fil: Fojon, Omar Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina
Fil: Rivarola, Roberto Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina
Fil: Hanssen, Jocelyn. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; Francia
Materia
IONIZATION
CAPTURE
DNA
CROSS SECTIONS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/268608
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/268608
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ionsChampion, ChristopheGalassi, Mariel ElisaLekadir, HacèneIncerti, SébastienFojon, Omar ArielRivarola, Roberto DanielHanssen, JocelynIONIZATIONCAPTUREDNACROSS SECTIONShttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1Although DNA lesions are considered of prime importance for describing the post-irradiation cellular survival, they still remain rarely studied on both experimental and theoretical sides. Under these conditions, we here propose different theoretical models for predicting the single ionization and single capture total cross sections for DNA bases impacted by protons.Material and methods: Three theoretical approaches are developed: a first classical one based on a classical trajectory Monte Carlo (CTMC) model and two quantum mechanical ones, namely, a Coulomb Born (CB1) and a continuum-distorted wave eikonal-initial-state (CDW-EIS) model. Results: Ionization and capture processes induced by protons on DNA bases (adenine, cytosine, thymine and guanine) are here studied in terms of total cross sections. Conclusions: A very good agreement is obtained between the different models at high enough impact velocities but discrepancies are observed between them at low impact energies (Ei<100 keV). Furthermore, it is shown that the theoretical cross sections underestimate the rare existing experimental data in particular for adenine and thymine whereas a reasonable agreement is found for cytosine.Fil: Champion, Christophe. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; FranciaFil: Galassi, Mariel Elisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; ArgentinaFil: Lekadir, Hacène. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; FranciaFil: Incerti, Sébastien. Universite de Bordeaux; FranciaFil: Fojon, Omar Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; ArgentinaFil: Rivarola, Roberto Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; ArgentinaFil: Hanssen, Jocelyn. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; FranciaTaylor & Francis Ltd2012-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/268608Champion, Christophe; Galassi, Mariel Elisa; Lekadir, Hacène; Incerti, Sébastien; Fojon, Omar Ariel; et al.; Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions; Taylor & Francis Ltd; International Journal Of Radiation Biology; 88; 1-2; 1-2012; 62-650955-3002CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3109/09553002.2011.626841info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.3109/09553002.2011.626841info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:45:25Zoai:ri.conicet.gov.ar:11336/268608instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:45:26.123CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
title Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
spellingShingle Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
Champion, Christophe
IONIZATION
CAPTURE
DNA
CROSS SECTIONS
title_short Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
title_full Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
title_fullStr Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
title_full_unstemmed Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
title_sort Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions
dc.creator.none.fl_str_mv Champion, Christophe
Galassi, Mariel Elisa
Lekadir, Hacène
Incerti, Sébastien
Fojon, Omar Ariel
Rivarola, Roberto Daniel
Hanssen, Jocelyn
author Champion, Christophe
author_facet Champion, Christophe
Galassi, Mariel Elisa
Lekadir, Hacène
Incerti, Sébastien
Fojon, Omar Ariel
Rivarola, Roberto Daniel
Hanssen, Jocelyn
author_role author
author2 Galassi, Mariel Elisa
Lekadir, Hacène
Incerti, Sébastien
Fojon, Omar Ariel
Rivarola, Roberto Daniel
Hanssen, Jocelyn
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv IONIZATION
CAPTURE
DNA
CROSS SECTIONS
topic IONIZATION
CAPTURE
DNA
CROSS SECTIONS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Although DNA lesions are considered of prime importance for describing the post-irradiation cellular survival, they still remain rarely studied on both experimental and theoretical sides. Under these conditions, we here propose different theoretical models for predicting the single ionization and single capture total cross sections for DNA bases impacted by protons.Material and methods: Three theoretical approaches are developed: a first classical one based on a classical trajectory Monte Carlo (CTMC) model and two quantum mechanical ones, namely, a Coulomb Born (CB1) and a continuum-distorted wave eikonal-initial-state (CDW-EIS) model. Results: Ionization and capture processes induced by protons on DNA bases (adenine, cytosine, thymine and guanine) are here studied in terms of total cross sections. Conclusions: A very good agreement is obtained between the different models at high enough impact velocities but discrepancies are observed between them at low impact energies (Ei<100 keV). Furthermore, it is shown that the theoretical cross sections underestimate the rare existing experimental data in particular for adenine and thymine whereas a reasonable agreement is found for cytosine.
Fil: Champion, Christophe. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; Francia
Fil: Galassi, Mariel Elisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina
Fil: Lekadir, Hacène. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; Francia
Fil: Incerti, Sébastien. Universite de Bordeaux; Francia
Fil: Fojon, Omar Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina
Fil: Rivarola, Roberto Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina
Fil: Hanssen, Jocelyn. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; Argentina. Université Paul Verlaine-Metz. Institut de Physique, Chimie et Materiaux. Laboratorie de Physique Moléculaire et des Collisions; Francia
description Although DNA lesions are considered of prime importance for describing the post-irradiation cellular survival, they still remain rarely studied on both experimental and theoretical sides. Under these conditions, we here propose different theoretical models for predicting the single ionization and single capture total cross sections for DNA bases impacted by protons.Material and methods: Three theoretical approaches are developed: a first classical one based on a classical trajectory Monte Carlo (CTMC) model and two quantum mechanical ones, namely, a Coulomb Born (CB1) and a continuum-distorted wave eikonal-initial-state (CDW-EIS) model. Results: Ionization and capture processes induced by protons on DNA bases (adenine, cytosine, thymine and guanine) are here studied in terms of total cross sections. Conclusions: A very good agreement is obtained between the different models at high enough impact velocities but discrepancies are observed between them at low impact energies (Ei<100 keV). Furthermore, it is shown that the theoretical cross sections underestimate the rare existing experimental data in particular for adenine and thymine whereas a reasonable agreement is found for cytosine.
publishDate 2012
dc.date.none.fl_str_mv 2012-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/268608
Champion, Christophe; Galassi, Mariel Elisa; Lekadir, Hacène; Incerti, Sébastien; Fojon, Omar Ariel; et al.; Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions; Taylor & Francis Ltd; International Journal Of Radiation Biology; 88; 1-2; 1-2012; 62-65
0955-3002
CONICET Digital
CONICET
url http://hdl.handle.net/11336/268608
identifier_str_mv Champion, Christophe; Galassi, Mariel Elisa; Lekadir, Hacène; Incerti, Sébastien; Fojon, Omar Ariel; et al.; Theoretical ionization and capture cross sections for DNA nucleobases impacted by light ions; Taylor & Francis Ltd; International Journal Of Radiation Biology; 88; 1-2; 1-2012; 62-65
0955-3002
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3109/09553002.2011.626841
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.3109/09553002.2011.626841
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis Ltd
publisher.none.fl_str_mv Taylor & Francis Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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