Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations

Autores
Mouresan, E. F.; Cañas Álvarez, J. J.; González Rodríguez, A.; Munilla Leguizamon, Sebastian; Altarriba, J.; Díaz, C.; Baró, J. A.; Molina, A.; Piedrafita, J.; Varona, Luisina
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study investigated the potential application of genomic selection under a multi-breed scheme in the Spanish autochthonous beef cattle populations using a simulation study that replicates the structure of linkage disequilibrium obtained from a sample of 25 triplets of sire/dam/offspring per population and using the BovineHD Beadchip. Purebred and combined reference sets were used for the genomic evaluation and several scenarios of different genetic architecture of the trait were investigated. The single-breed evaluations yielded the highest within-breed accuracies. Across breed accuracies were found low but positive on average confirming the genetic connectedness between the populations. If the same genotyping effort is split in several populations, the accuracies were lower when compared with single-breed evaluation, but showed a small advantage over small-sized purebred reference sets over the accuracies of subsequent generations. Besides, the genetic architecture of the trait did not show any relevant effect on the accuracy with the exception of rare variants, which yielded slightly lower results and higher loss of predictive ability over the generations.
Fil: Mouresan, E. F.. Universidad de Zaragoza; España
Fil: Cañas Álvarez, J. J.. Universitat Autònoma de Barcelona; España
Fil: González Rodríguez, A.. Universidad de Zaragoza; España
Fil: Munilla Leguizamon, Sebastian. Universidad de Zaragoza; España. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Altarriba, J.. Universidad de Zaragoza; España. Instituto Agroalimentario de Aragón; España
Fil: Díaz, C.. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria; España
Fil: Baró, J. A.. Universidad de Valladolid; España
Fil: Molina, A.. Universidad de Córdoba; España
Fil: Piedrafita, J.. Universitat Autònoma de Barcelona; España
Fil: Varona, Luisina. Universidad de Zaragoza; España
Materia
ACCURACY
ACROSS POPULATION
BEEF CATTLE
GENOMIC SELECTION
META-POPULATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/96155
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/96155
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populationsMouresan, E. F.Cañas Álvarez, J. J.González Rodríguez, A.Munilla Leguizamon, SebastianAltarriba, J.Díaz, C.Baró, J. A.Molina, A.Piedrafita, J.Varona, LuisinaACCURACYACROSS POPULATIONBEEF CATTLEGENOMIC SELECTIONMETA-POPULATIONhttps://purl.org/becyt/ford/4.2https://purl.org/becyt/ford/4This study investigated the potential application of genomic selection under a multi-breed scheme in the Spanish autochthonous beef cattle populations using a simulation study that replicates the structure of linkage disequilibrium obtained from a sample of 25 triplets of sire/dam/offspring per population and using the BovineHD Beadchip. Purebred and combined reference sets were used for the genomic evaluation and several scenarios of different genetic architecture of the trait were investigated. The single-breed evaluations yielded the highest within-breed accuracies. Across breed accuracies were found low but positive on average confirming the genetic connectedness between the populations. If the same genotyping effort is split in several populations, the accuracies were lower when compared with single-breed evaluation, but showed a small advantage over small-sized purebred reference sets over the accuracies of subsequent generations. Besides, the genetic architecture of the trait did not show any relevant effect on the accuracy with the exception of rare variants, which yielded slightly lower results and higher loss of predictive ability over the generations.Fil: Mouresan, E. F.. Universidad de Zaragoza; EspañaFil: Cañas Álvarez, J. J.. Universitat Autònoma de Barcelona; EspañaFil: González Rodríguez, A.. Universidad de Zaragoza; EspañaFil: Munilla Leguizamon, Sebastian. Universidad de Zaragoza; España. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Altarriba, J.. Universidad de Zaragoza; España. Instituto Agroalimentario de Aragón; EspañaFil: Díaz, C.. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria; EspañaFil: Baró, J. A.. Universidad de Valladolid; EspañaFil: Molina, A.. Universidad de Córdoba; EspañaFil: Piedrafita, J.. Universitat Autònoma de Barcelona; EspañaFil: Varona, Luisina. Universidad de Zaragoza; EspañaCambridge University Press2018-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/96155Mouresan, E. F.; Cañas Álvarez, J. J.; González Rodríguez, A.; Munilla Leguizamon, Sebastian; Altarriba, J.; et al.; Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations; Cambridge University Press; Animal; 12; 7; 7-2018; 1350-13571751-7311CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1017/S175173111700283Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:14:28Zoai:ri.conicet.gov.ar:11336/96155instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:14:28.566CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
title Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
spellingShingle Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
Mouresan, E. F.
ACCURACY
ACROSS POPULATION
BEEF CATTLE
GENOMIC SELECTION
META-POPULATION
title_short Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
title_full Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
title_fullStr Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
title_full_unstemmed Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
title_sort Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations
dc.creator.none.fl_str_mv Mouresan, E. F.
Cañas Álvarez, J. J.
González Rodríguez, A.
Munilla Leguizamon, Sebastian
Altarriba, J.
Díaz, C.
Baró, J. A.
Molina, A.
Piedrafita, J.
Varona, Luisina
author Mouresan, E. F.
author_facet Mouresan, E. F.
Cañas Álvarez, J. J.
González Rodríguez, A.
Munilla Leguizamon, Sebastian
Altarriba, J.
Díaz, C.
Baró, J. A.
Molina, A.
Piedrafita, J.
Varona, Luisina
author_role author
author2 Cañas Álvarez, J. J.
González Rodríguez, A.
Munilla Leguizamon, Sebastian
Altarriba, J.
Díaz, C.
Baró, J. A.
Molina, A.
Piedrafita, J.
Varona, Luisina
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv ACCURACY
ACROSS POPULATION
BEEF CATTLE
GENOMIC SELECTION
META-POPULATION
topic ACCURACY
ACROSS POPULATION
BEEF CATTLE
GENOMIC SELECTION
META-POPULATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.2
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv This study investigated the potential application of genomic selection under a multi-breed scheme in the Spanish autochthonous beef cattle populations using a simulation study that replicates the structure of linkage disequilibrium obtained from a sample of 25 triplets of sire/dam/offspring per population and using the BovineHD Beadchip. Purebred and combined reference sets were used for the genomic evaluation and several scenarios of different genetic architecture of the trait were investigated. The single-breed evaluations yielded the highest within-breed accuracies. Across breed accuracies were found low but positive on average confirming the genetic connectedness between the populations. If the same genotyping effort is split in several populations, the accuracies were lower when compared with single-breed evaluation, but showed a small advantage over small-sized purebred reference sets over the accuracies of subsequent generations. Besides, the genetic architecture of the trait did not show any relevant effect on the accuracy with the exception of rare variants, which yielded slightly lower results and higher loss of predictive ability over the generations.
Fil: Mouresan, E. F.. Universidad de Zaragoza; España
Fil: Cañas Álvarez, J. J.. Universitat Autònoma de Barcelona; España
Fil: González Rodríguez, A.. Universidad de Zaragoza; España
Fil: Munilla Leguizamon, Sebastian. Universidad de Zaragoza; España. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Animal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Altarriba, J.. Universidad de Zaragoza; España. Instituto Agroalimentario de Aragón; España
Fil: Díaz, C.. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria; España
Fil: Baró, J. A.. Universidad de Valladolid; España
Fil: Molina, A.. Universidad de Córdoba; España
Fil: Piedrafita, J.. Universitat Autònoma de Barcelona; España
Fil: Varona, Luisina. Universidad de Zaragoza; España
description This study investigated the potential application of genomic selection under a multi-breed scheme in the Spanish autochthonous beef cattle populations using a simulation study that replicates the structure of linkage disequilibrium obtained from a sample of 25 triplets of sire/dam/offspring per population and using the BovineHD Beadchip. Purebred and combined reference sets were used for the genomic evaluation and several scenarios of different genetic architecture of the trait were investigated. The single-breed evaluations yielded the highest within-breed accuracies. Across breed accuracies were found low but positive on average confirming the genetic connectedness between the populations. If the same genotyping effort is split in several populations, the accuracies were lower when compared with single-breed evaluation, but showed a small advantage over small-sized purebred reference sets over the accuracies of subsequent generations. Besides, the genetic architecture of the trait did not show any relevant effect on the accuracy with the exception of rare variants, which yielded slightly lower results and higher loss of predictive ability over the generations.
publishDate 2018
dc.date.none.fl_str_mv 2018-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/96155
Mouresan, E. F.; Cañas Álvarez, J. J.; González Rodríguez, A.; Munilla Leguizamon, Sebastian; Altarriba, J.; et al.; Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations; Cambridge University Press; Animal; 12; 7; 7-2018; 1350-1357
1751-7311
CONICET Digital
CONICET
url http://hdl.handle.net/11336/96155
identifier_str_mv Mouresan, E. F.; Cañas Álvarez, J. J.; González Rodríguez, A.; Munilla Leguizamon, Sebastian; Altarriba, J.; et al.; Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations; Cambridge University Press; Animal; 12; 7; 7-2018; 1350-1357
1751-7311
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1017/S175173111700283X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980773384159232
score 12.993085

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