Induction of nitric oxide synthase activity in adrenal cells

Autores
Cymeryng, Cora Betriz; Lotito, S.P.; Colonna, C.; Cornejo Maciel, Maria Fabiana; Podestá, E. J.
Año de publicación
2000
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The induction of nitric oxide synthase (NOS) II by bacterial lypopolysaccharide (LPS) was studied in a steroidogenic mouse tumor adrenal cell line (Y1). Conditioned media from LPS-stimulated peritoneal macrophages induced an increase in NOS II expression as shown by western and northern blot analysis. Accordingly, in the presence of conditioned media an increase in nitrite levels was observed. In addition, steroid production was significantly decreased. In conclusion, NOS II expression could be induced in steroidogenic cells with a concomitant inhibition of steroid production.
Fil: Cymeryng, Cora Betriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Lotito, S.P.. Universidad de Buenos Aires; Argentina
Fil: Colonna, C.. Universidad de Buenos Aires; Argentina
Fil: Cornejo Maciel, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Podestá, E. J.. Universidad de Buenos Aires; Argentina
Materia
nitric oxide synthase
adrenal cells
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/152087
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Induction of nitric oxide synthase activity in adrenal cellsCymeryng, Cora BetrizLotito, S.P.Colonna, C.Cornejo Maciel, Maria FabianaPodestá, E. J.nitric oxide synthaseadrenal cellshttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The induction of nitric oxide synthase (NOS) II by bacterial lypopolysaccharide (LPS) was studied in a steroidogenic mouse tumor adrenal cell line (Y1). Conditioned media from LPS-stimulated peritoneal macrophages induced an increase in NOS II expression as shown by western and northern blot analysis. Accordingly, in the presence of conditioned media an increase in nitrite levels was observed. In addition, steroid production was significantly decreased. In conclusion, NOS II expression could be induced in steroidogenic cells with a concomitant inhibition of steroid production.Fil: Cymeryng, Cora Betriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Lotito, S.P.. Universidad de Buenos Aires; ArgentinaFil: Colonna, C.. Universidad de Buenos Aires; ArgentinaFil: Cornejo Maciel, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Podestá, E. J.. Universidad de Buenos Aires; ArgentinaTaylor & Francis2000-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/152087Cymeryng, Cora Betriz; Lotito, S.P.; Colonna, C.; Cornejo Maciel, Maria Fabiana; Podestá, E. J.; Induction of nitric oxide synthase activity in adrenal cells; Taylor & Francis; Endocrine Research; 26; 4; 12-2000; 589-5950743-5800CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3109/07435800009048576info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.3109/07435800009048576info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:52:35Zoai:ri.conicet.gov.ar:11336/152087instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:52:35.428CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Induction of nitric oxide synthase activity in adrenal cells
title Induction of nitric oxide synthase activity in adrenal cells
spellingShingle Induction of nitric oxide synthase activity in adrenal cells
Cymeryng, Cora Betriz
nitric oxide synthase
adrenal cells
title_short Induction of nitric oxide synthase activity in adrenal cells
title_full Induction of nitric oxide synthase activity in adrenal cells
title_fullStr Induction of nitric oxide synthase activity in adrenal cells
title_full_unstemmed Induction of nitric oxide synthase activity in adrenal cells
title_sort Induction of nitric oxide synthase activity in adrenal cells
dc.creator.none.fl_str_mv Cymeryng, Cora Betriz
Lotito, S.P.
Colonna, C.
Cornejo Maciel, Maria Fabiana
Podestá, E. J.
author Cymeryng, Cora Betriz
author_facet Cymeryng, Cora Betriz
Lotito, S.P.
Colonna, C.
Cornejo Maciel, Maria Fabiana
Podestá, E. J.
author_role author
author2 Lotito, S.P.
Colonna, C.
Cornejo Maciel, Maria Fabiana
Podestá, E. J.
author2_role author
author
author
author
dc.subject.none.fl_str_mv nitric oxide synthase
adrenal cells
topic nitric oxide synthase
adrenal cells
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The induction of nitric oxide synthase (NOS) II by bacterial lypopolysaccharide (LPS) was studied in a steroidogenic mouse tumor adrenal cell line (Y1). Conditioned media from LPS-stimulated peritoneal macrophages induced an increase in NOS II expression as shown by western and northern blot analysis. Accordingly, in the presence of conditioned media an increase in nitrite levels was observed. In addition, steroid production was significantly decreased. In conclusion, NOS II expression could be induced in steroidogenic cells with a concomitant inhibition of steroid production.
Fil: Cymeryng, Cora Betriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Lotito, S.P.. Universidad de Buenos Aires; Argentina
Fil: Colonna, C.. Universidad de Buenos Aires; Argentina
Fil: Cornejo Maciel, Maria Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentina
Fil: Podestá, E. J.. Universidad de Buenos Aires; Argentina
description The induction of nitric oxide synthase (NOS) II by bacterial lypopolysaccharide (LPS) was studied in a steroidogenic mouse tumor adrenal cell line (Y1). Conditioned media from LPS-stimulated peritoneal macrophages induced an increase in NOS II expression as shown by western and northern blot analysis. Accordingly, in the presence of conditioned media an increase in nitrite levels was observed. In addition, steroid production was significantly decreased. In conclusion, NOS II expression could be induced in steroidogenic cells with a concomitant inhibition of steroid production.
publishDate 2000
dc.date.none.fl_str_mv 2000-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/152087
Cymeryng, Cora Betriz; Lotito, S.P.; Colonna, C.; Cornejo Maciel, Maria Fabiana; Podestá, E. J.; Induction of nitric oxide synthase activity in adrenal cells; Taylor & Francis; Endocrine Research; 26; 4; 12-2000; 589-595
0743-5800
CONICET Digital
CONICET
url http://hdl.handle.net/11336/152087
identifier_str_mv Cymeryng, Cora Betriz; Lotito, S.P.; Colonna, C.; Cornejo Maciel, Maria Fabiana; Podestá, E. J.; Induction of nitric oxide synthase activity in adrenal cells; Taylor & Francis; Endocrine Research; 26; 4; 12-2000; 589-595
0743-5800
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3109/07435800009048576
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.3109/07435800009048576
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269168681877504
score 13.13397

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