Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family

Autores
Torres Carro, Romina; Alberto, Maria Rosa; Isla, Maria Ines
Año de publicación
2012
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Usage of medicinal plants with curative purpose is an ancient and common practice still in use now a day. On physiopathology of sicknesses that develop an inflammatory and allergic process, lipoxygenase (LOX) has an important role being the enzymes responsible of the biosynthesis of inflammatory mediators. We evaluated the anti-LOX capacity of alcoholic extracts of nine plant species (B. boliviensis, B. incarum, Ch. keidelii, C. atacamensis, N. armatum, P. lepidophylla, P. lucida, P. phyliciformis, T. absinthioides) belonging to Asteraceae family and its relation to its phytochemical profile. Tinctures of plants collected in Argentine Puna were analyzed. Total polyphenols content vary between 64-160 µg Gallic Acid Equivalents, GAE/mg, phenolics non flavonoids vary between 53- 153 µg GAE/mg, flavones/flavonols between 6- 28 µg Quercetin Equivalents/mg and flavonones/dihidroflavonones between 24 and 51 µg Naringenin Equivalents/mg. Species from genus Parastrephia presented the highest inhibitory activity over LOX with IC50 values between 219 and 253 µg/ml, being P. lepidophylla the most active one. This could be related to the higher levels of total phenolics and flavones/flavonols measured in this species. The results indicate the potential use of Parastrephia extracts as natural anti-inflammatory.
Fil: Torres Carro, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
XXVIII Jornadas Científicas de la Asociación de Biología de Tucumán
Tafí del Valle
Argentina
Asociación de Biología de Tucumán
Materia
Lipoxygenase enzyme
Astereaceae
Medicinal Plants
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/261330
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/261330
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae familyTorres Carro, RominaAlberto, Maria RosaIsla, Maria InesLipoxygenase enzymeAstereaceaeMedicinal Plantshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Usage of medicinal plants with curative purpose is an ancient and common practice still in use now a day. On physiopathology of sicknesses that develop an inflammatory and allergic process, lipoxygenase (LOX) has an important role being the enzymes responsible of the biosynthesis of inflammatory mediators. We evaluated the anti-LOX capacity of alcoholic extracts of nine plant species (B. boliviensis, B. incarum, Ch. keidelii, C. atacamensis, N. armatum, P. lepidophylla, P. lucida, P. phyliciformis, T. absinthioides) belonging to Asteraceae family and its relation to its phytochemical profile. Tinctures of plants collected in Argentine Puna were analyzed. Total polyphenols content vary between 64-160 µg Gallic Acid Equivalents, GAE/mg, phenolics non flavonoids vary between 53- 153 µg GAE/mg, flavones/flavonols between 6- 28 µg Quercetin Equivalents/mg and flavonones/dihidroflavonones between 24 and 51 µg Naringenin Equivalents/mg. Species from genus Parastrephia presented the highest inhibitory activity over LOX with IC50 values between 219 and 253 µg/ml, being P. lepidophylla the most active one. This could be related to the higher levels of total phenolics and flavones/flavonols measured in this species. The results indicate the potential use of Parastrephia extracts as natural anti-inflammatory.Fil: Torres Carro, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaXXVIII Jornadas Científicas de la Asociación de Biología de TucumánTafí del ValleArgentinaAsociación de Biología de TucumánTech Science Press2012info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectJornadaJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/mswordapplication/pdfhttp://hdl.handle.net/11336/261330Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family; XXVIII Jornadas Científicas de la Asociación de Biología de Tucumán; Tafí del Valle; Argentina; 2011; 71-710327-9545CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://asobioltuc.com/listado.php?id=2Nacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:33:35Zoai:ri.conicet.gov.ar:11336/261330instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:33:36.232CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
title Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
spellingShingle Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
Torres Carro, Romina
Lipoxygenase enzyme
Astereaceae
Medicinal Plants
title_short Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
title_full Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
title_fullStr Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
title_full_unstemmed Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
title_sort Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family
dc.creator.none.fl_str_mv Torres Carro, Romina
Alberto, Maria Rosa
Isla, Maria Ines
author Torres Carro, Romina
author_facet Torres Carro, Romina
Alberto, Maria Rosa
Isla, Maria Ines
author_role author
author2 Alberto, Maria Rosa
Isla, Maria Ines
author2_role author
author
dc.subject.none.fl_str_mv Lipoxygenase enzyme
Astereaceae
Medicinal Plants
topic Lipoxygenase enzyme
Astereaceae
Medicinal Plants
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Usage of medicinal plants with curative purpose is an ancient and common practice still in use now a day. On physiopathology of sicknesses that develop an inflammatory and allergic process, lipoxygenase (LOX) has an important role being the enzymes responsible of the biosynthesis of inflammatory mediators. We evaluated the anti-LOX capacity of alcoholic extracts of nine plant species (B. boliviensis, B. incarum, Ch. keidelii, C. atacamensis, N. armatum, P. lepidophylla, P. lucida, P. phyliciformis, T. absinthioides) belonging to Asteraceae family and its relation to its phytochemical profile. Tinctures of plants collected in Argentine Puna were analyzed. Total polyphenols content vary between 64-160 µg Gallic Acid Equivalents, GAE/mg, phenolics non flavonoids vary between 53- 153 µg GAE/mg, flavones/flavonols between 6- 28 µg Quercetin Equivalents/mg and flavonones/dihidroflavonones between 24 and 51 µg Naringenin Equivalents/mg. Species from genus Parastrephia presented the highest inhibitory activity over LOX with IC50 values between 219 and 253 µg/ml, being P. lepidophylla the most active one. This could be related to the higher levels of total phenolics and flavones/flavonols measured in this species. The results indicate the potential use of Parastrephia extracts as natural anti-inflammatory.
Fil: Torres Carro, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Alberto, Maria Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
XXVIII Jornadas Científicas de la Asociación de Biología de Tucumán
Tafí del Valle
Argentina
Asociación de Biología de Tucumán
description Usage of medicinal plants with curative purpose is an ancient and common practice still in use now a day. On physiopathology of sicknesses that develop an inflammatory and allergic process, lipoxygenase (LOX) has an important role being the enzymes responsible of the biosynthesis of inflammatory mediators. We evaluated the anti-LOX capacity of alcoholic extracts of nine plant species (B. boliviensis, B. incarum, Ch. keidelii, C. atacamensis, N. armatum, P. lepidophylla, P. lucida, P. phyliciformis, T. absinthioides) belonging to Asteraceae family and its relation to its phytochemical profile. Tinctures of plants collected in Argentine Puna were analyzed. Total polyphenols content vary between 64-160 µg Gallic Acid Equivalents, GAE/mg, phenolics non flavonoids vary between 53- 153 µg GAE/mg, flavones/flavonols between 6- 28 µg Quercetin Equivalents/mg and flavonones/dihidroflavonones between 24 and 51 µg Naringenin Equivalents/mg. Species from genus Parastrephia presented the highest inhibitory activity over LOX with IC50 values between 219 and 253 µg/ml, being P. lepidophylla the most active one. This could be related to the higher levels of total phenolics and flavones/flavonols measured in this species. The results indicate the potential use of Parastrephia extracts as natural anti-inflammatory.
publishDate 2012
dc.date.none.fl_str_mv 2012
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Jornada
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/261330
Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family; XXVIII Jornadas Científicas de la Asociación de Biología de Tucumán; Tafí del Valle; Argentina; 2011; 71-71
0327-9545
CONICET Digital
CONICET
url http://hdl.handle.net/11336/261330
identifier_str_mv Phytochemical profile and anti-lipoxygenase activity of alcoholic extracts of plant species from asteraceae family; XXVIII Jornadas Científicas de la Asociación de Biología de Tucumán; Tafí del Valle; Argentina; 2011; 71-71
0327-9545
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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dc.coverage.none.fl_str_mv Nacional
dc.publisher.none.fl_str_mv Tech Science Press
publisher.none.fl_str_mv Tech Science Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
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instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
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repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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