Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture

Autores
Peñaherrera Pazmiño, Ana Belén; Rosero, Gustavo Iván; Perez, Maximiliano Sebastian; Lerner, Betiana
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Flexographic printing, traditionally used in the packaging industry, has emerged as a promising technology for microfluidic device fabrication due to enabling high resolution and being commercially available at a low cost compared to conventional techniques. This review explores the adaptation of a photopolymer flexographic printing plate mold (FMold) for microfluidics, examining its advantages, challenges, and applications. It offers a state-of-the-art view of the application of FMold for microfluidic systems, which offers a unique opportunity in terms of cost-effectiveness, scalability, and rapid prototyping. Applications are diverse: FMold has enabled the fabrication of microfluidic devices used in enhanced oil recovery to prepare rock-on-a-chip models, droplet generation and storage, suspension cell culture, monoclonal antibody production, complex cell differentiation pattern creation, phage screening, drug screening, cell detection, and cancer stem cell culture. Since its first appearance in 2018, FMold has been utilized in 50 publications in different laboratories around the world. Key advancements, current research trends, and future prospects are discussed to provide a comprehensive overview of this evolving tool.
Fil: Peñaherrera Pazmiño, Ana Belén. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rosero, Gustavo Iván. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina
Fil: Perez, Maximiliano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina
Fil: Lerner, Betiana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina
Materia
flexography
microfluidics
sustainable development goal 3
cell culture
sustainable development goal 10
biomedicine
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/267924
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic ManufacturePeñaherrera Pazmiño, Ana BelénRosero, Gustavo IvánPerez, Maximiliano SebastianLerner, Betianaflexographymicrofluidicssustainable development goal 3cell culturesustainable development goal 10biomedicinehttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1Flexographic printing, traditionally used in the packaging industry, has emerged as a promising technology for microfluidic device fabrication due to enabling high resolution and being commercially available at a low cost compared to conventional techniques. This review explores the adaptation of a photopolymer flexographic printing plate mold (FMold) for microfluidics, examining its advantages, challenges, and applications. It offers a state-of-the-art view of the application of FMold for microfluidic systems, which offers a unique opportunity in terms of cost-effectiveness, scalability, and rapid prototyping. Applications are diverse: FMold has enabled the fabrication of microfluidic devices used in enhanced oil recovery to prepare rock-on-a-chip models, droplet generation and storage, suspension cell culture, monoclonal antibody production, complex cell differentiation pattern creation, phage screening, drug screening, cell detection, and cancer stem cell culture. Since its first appearance in 2018, FMold has been utilized in 50 publications in different laboratories around the world. Key advancements, current research trends, and future prospects are discussed to provide a comprehensive overview of this evolving tool.Fil: Peñaherrera Pazmiño, Ana Belén. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rosero, Gustavo Iván. Universidad Tecnológica Nacional. Facultad Regional Haedo; ArgentinaFil: Perez, Maximiliano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; ArgentinaFil: Lerner, Betiana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; ArgentinaMDPI2025-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/267924Peñaherrera Pazmiño, Ana Belén; Rosero, Gustavo Iván; Perez, Maximiliano Sebastian; Lerner, Betiana; Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture; MDPI; Polymers; 17; 13; 6-2025; 1-332073-4360CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2073-4360/17/13/1723info:eu-repo/semantics/altIdentifier/doi/10.3390/polym17131723info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:38:34Zoai:ri.conicet.gov.ar:11336/267924instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:38:35.156CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
title Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
spellingShingle Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
Peñaherrera Pazmiño, Ana Belén
flexography
microfluidics
sustainable development goal 3
cell culture
sustainable development goal 10
biomedicine
title_short Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
title_full Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
title_fullStr Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
title_full_unstemmed Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
title_sort Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture
dc.creator.none.fl_str_mv Peñaherrera Pazmiño, Ana Belén
Rosero, Gustavo Iván
Perez, Maximiliano Sebastian
Lerner, Betiana
author Peñaherrera Pazmiño, Ana Belén
author_facet Peñaherrera Pazmiño, Ana Belén
Rosero, Gustavo Iván
Perez, Maximiliano Sebastian
Lerner, Betiana
author_role author
author2 Rosero, Gustavo Iván
Perez, Maximiliano Sebastian
Lerner, Betiana
author2_role author
author
author
dc.subject.none.fl_str_mv flexography
microfluidics
sustainable development goal 3
cell culture
sustainable development goal 10
biomedicine
topic flexography
microfluidics
sustainable development goal 3
cell culture
sustainable development goal 10
biomedicine
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Flexographic printing, traditionally used in the packaging industry, has emerged as a promising technology for microfluidic device fabrication due to enabling high resolution and being commercially available at a low cost compared to conventional techniques. This review explores the adaptation of a photopolymer flexographic printing plate mold (FMold) for microfluidics, examining its advantages, challenges, and applications. It offers a state-of-the-art view of the application of FMold for microfluidic systems, which offers a unique opportunity in terms of cost-effectiveness, scalability, and rapid prototyping. Applications are diverse: FMold has enabled the fabrication of microfluidic devices used in enhanced oil recovery to prepare rock-on-a-chip models, droplet generation and storage, suspension cell culture, monoclonal antibody production, complex cell differentiation pattern creation, phage screening, drug screening, cell detection, and cancer stem cell culture. Since its first appearance in 2018, FMold has been utilized in 50 publications in different laboratories around the world. Key advancements, current research trends, and future prospects are discussed to provide a comprehensive overview of this evolving tool.
Fil: Peñaherrera Pazmiño, Ana Belén. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rosero, Gustavo Iván. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina
Fil: Perez, Maximiliano Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina
Fil: Lerner, Betiana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional. Facultad Regional Haedo; Argentina
description Flexographic printing, traditionally used in the packaging industry, has emerged as a promising technology for microfluidic device fabrication due to enabling high resolution and being commercially available at a low cost compared to conventional techniques. This review explores the adaptation of a photopolymer flexographic printing plate mold (FMold) for microfluidics, examining its advantages, challenges, and applications. It offers a state-of-the-art view of the application of FMold for microfluidic systems, which offers a unique opportunity in terms of cost-effectiveness, scalability, and rapid prototyping. Applications are diverse: FMold has enabled the fabrication of microfluidic devices used in enhanced oil recovery to prepare rock-on-a-chip models, droplet generation and storage, suspension cell culture, monoclonal antibody production, complex cell differentiation pattern creation, phage screening, drug screening, cell detection, and cancer stem cell culture. Since its first appearance in 2018, FMold has been utilized in 50 publications in different laboratories around the world. Key advancements, current research trends, and future prospects are discussed to provide a comprehensive overview of this evolving tool.
publishDate 2025
dc.date.none.fl_str_mv 2025-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/267924
Peñaherrera Pazmiño, Ana Belén; Rosero, Gustavo Iván; Perez, Maximiliano Sebastian; Lerner, Betiana; Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture; MDPI; Polymers; 17; 13; 6-2025; 1-33
2073-4360
CONICET Digital
CONICET
url http://hdl.handle.net/11336/267924
identifier_str_mv Peñaherrera Pazmiño, Ana Belén; Rosero, Gustavo Iván; Perez, Maximiliano Sebastian; Lerner, Betiana; Photopolymer Flexographic Printing Plate Mold for PDMS Microfluidic Manufacture; MDPI; Polymers; 17; 13; 6-2025; 1-33
2073-4360
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2073-4360/17/13/1723
info:eu-repo/semantics/altIdentifier/doi/10.3390/polym17131723
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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