Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water
- Autores
- Ossana, Natalia Alejandra; Eissa, Bettina Lorena; Baudou, Federico Gastón; Castañé, Patricia Mónica; Soloneski, Sonia Maria Elsa; Ferrari, Lucrecia
- Año de publicación
- 2016
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The aim of this paper is to assess the water quality to chemical pollution at Roggero Dam, the headwater of the Reconquista river, and to perform a Cadmium (Cd) contamination pulse simulation through a wide battery of biomarkers which included: genotoxicity and enzymatic biomarker parameters on a neotropical teleost fish namely Cnesterodon decemmaculatus. Water samples were taken in order to determine the river's physicochemical profile. An integrative approach was applied using a biomarker index. The bioassay involved the use of laboratory culture adult animals, acclimatized in moderately hard water (MHW) and fed ad libitum. A semi-static 96 h bioassay was conducted and the experimental groups were as follows: [1] river water (Rg); [2] river water + 2 mg/L Cd (RgCd); [3] MHW + 2 mg/L Cadmium (Cd), positive metal control; [4] MHW + 5 mg/L Cyclophosphamide (positive genotoxicity control -CP); [5] MWH, negative control (NC). At the end of the exposure time fishes were sectioned and the following biomarkers were determined: 1) condition factor rate (CF); 2) for the anterior section (A) (head): glutathione (GSH) and protein (Pr) content; 3) for the body midsection (M) (viscera): Pr, GSH, Glutathione-S-transferase (GST), catalase (CAT) and superoxide dismutase (SOD). Blood samples were also taken from the fish specimens to estimate the frequency of micronuclei (MN) as well as other nuclear abnormalities (NA). The physicochemical profile of the river water sample indicated high Copper concentrations. CAT and SOD activity and total Pr content did not show any significant changes. GST activity decreased in fish exposed to Rg, while GSH content decreased significantly for all treatments compared to controls in MHW. These results would seem to point to a reduction in cell defense capability as a result of the depletion antioxidants such as GSH. The NA frequency increased significantly in all treated groups while MN frequency was increased only in Cd and CP groups. Using some the biomarkers measured, a biomarker index was estimated which revealed that fish exposed to Rg were 90% affected or highly affected, while those exposed to RgCd were 80% and Cd 68% affected or highly affected. The obtained results indicate the usefulness of the use of a battery of variables by means of the biomarker index to analyze water quality.
Fil: Ossana, Natalia Alejandra. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina
Fil: Eissa, Bettina Lorena. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina
Fil: Baudou, Federico Gastón. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina. Ministerio de Ciencia. Tecnología e Innovación Productiva. Agencia Nacional de Promoción Científica y Tecnológica; Argentina
Fil: Castañé, Patricia Mónica. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina
Fil: Soloneski, Sonia Maria Elsa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; Argentina
Fil: Ferrari, Lucrecia. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina - Materia
-
BIOMARKER INDEX
CADMIUM
CNESTERODON DECEMMACULATUS
GENOTOXICITY
OXIDATIVE STRESS
RECONQUISTA RIVER - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/114765
Ver los metadatos del registro completo
id |
CONICETDig_d1c8bf435f31650e0b756f28da9136fc |
---|---|
oai_identifier_str |
oai:ri.conicet.gov.ar:11336/114765 |
network_acronym_str |
CONICETDig |
repository_id_str |
3498 |
network_name_str |
CONICET Digital (CONICET) |
spelling |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river waterOssana, Natalia AlejandraEissa, Bettina LorenaBaudou, Federico GastónCastañé, Patricia MónicaSoloneski, Sonia Maria ElsaFerrari, LucreciaBIOMARKER INDEXCADMIUMCNESTERODON DECEMMACULATUSGENOTOXICITYOXIDATIVE STRESSRECONQUISTA RIVERhttps://purl.org/becyt/ford/1.5https://purl.org/becyt/ford/1The aim of this paper is to assess the water quality to chemical pollution at Roggero Dam, the headwater of the Reconquista river, and to perform a Cadmium (Cd) contamination pulse simulation through a wide battery of biomarkers which included: genotoxicity and enzymatic biomarker parameters on a neotropical teleost fish namely Cnesterodon decemmaculatus. Water samples were taken in order to determine the river's physicochemical profile. An integrative approach was applied using a biomarker index. The bioassay involved the use of laboratory culture adult animals, acclimatized in moderately hard water (MHW) and fed ad libitum. A semi-static 96 h bioassay was conducted and the experimental groups were as follows: [1] river water (Rg); [2] river water + 2 mg/L Cd (RgCd); [3] MHW + 2 mg/L Cadmium (Cd), positive metal control; [4] MHW + 5 mg/L Cyclophosphamide (positive genotoxicity control -CP); [5] MWH, negative control (NC). At the end of the exposure time fishes were sectioned and the following biomarkers were determined: 1) condition factor rate (CF); 2) for the anterior section (A) (head): glutathione (GSH) and protein (Pr) content; 3) for the body midsection (M) (viscera): Pr, GSH, Glutathione-S-transferase (GST), catalase (CAT) and superoxide dismutase (SOD). Blood samples were also taken from the fish specimens to estimate the frequency of micronuclei (MN) as well as other nuclear abnormalities (NA). The physicochemical profile of the river water sample indicated high Copper concentrations. CAT and SOD activity and total Pr content did not show any significant changes. GST activity decreased in fish exposed to Rg, while GSH content decreased significantly for all treatments compared to controls in MHW. These results would seem to point to a reduction in cell defense capability as a result of the depletion antioxidants such as GSH. The NA frequency increased significantly in all treated groups while MN frequency was increased only in Cd and CP groups. Using some the biomarkers measured, a biomarker index was estimated which revealed that fish exposed to Rg were 90% affected or highly affected, while those exposed to RgCd were 80% and Cd 68% affected or highly affected. The obtained results indicate the usefulness of the use of a battery of variables by means of the biomarker index to analyze water quality.Fil: Ossana, Natalia Alejandra. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; ArgentinaFil: Eissa, Bettina Lorena. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; ArgentinaFil: Baudou, Federico Gastón. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina. Ministerio de Ciencia. Tecnología e Innovación Productiva. Agencia Nacional de Promoción Científica y Tecnológica; ArgentinaFil: Castañé, Patricia Mónica. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; ArgentinaFil: Soloneski, Sonia Maria Elsa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; ArgentinaFil: Ferrari, Lucrecia. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaAcademic Press Inc Elsevier Science2016-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/114765Ossana, Natalia Alejandra; Eissa, Bettina Lorena; Baudou, Federico Gastón; Castañé, Patricia Mónica; Soloneski, Sonia Maria Elsa; et al.; Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water; Academic Press Inc Elsevier Science; Ecotoxicology and Environmental Safety; 133; 11-2016; 73-810147-6513CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0147651316302524info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ecoenv.2016.06.046info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:52:36Zoai:ri.conicet.gov.ar:11336/114765instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:52:36.31CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
title |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
spellingShingle |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water Ossana, Natalia Alejandra BIOMARKER INDEX CADMIUM CNESTERODON DECEMMACULATUS GENOTOXICITY OXIDATIVE STRESS RECONQUISTA RIVER |
title_short |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
title_full |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
title_fullStr |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
title_full_unstemmed |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
title_sort |
Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water |
dc.creator.none.fl_str_mv |
Ossana, Natalia Alejandra Eissa, Bettina Lorena Baudou, Federico Gastón Castañé, Patricia Mónica Soloneski, Sonia Maria Elsa Ferrari, Lucrecia |
author |
Ossana, Natalia Alejandra |
author_facet |
Ossana, Natalia Alejandra Eissa, Bettina Lorena Baudou, Federico Gastón Castañé, Patricia Mónica Soloneski, Sonia Maria Elsa Ferrari, Lucrecia |
author_role |
author |
author2 |
Eissa, Bettina Lorena Baudou, Federico Gastón Castañé, Patricia Mónica Soloneski, Sonia Maria Elsa Ferrari, Lucrecia |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
BIOMARKER INDEX CADMIUM CNESTERODON DECEMMACULATUS GENOTOXICITY OXIDATIVE STRESS RECONQUISTA RIVER |
topic |
BIOMARKER INDEX CADMIUM CNESTERODON DECEMMACULATUS GENOTOXICITY OXIDATIVE STRESS RECONQUISTA RIVER |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.5 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
The aim of this paper is to assess the water quality to chemical pollution at Roggero Dam, the headwater of the Reconquista river, and to perform a Cadmium (Cd) contamination pulse simulation through a wide battery of biomarkers which included: genotoxicity and enzymatic biomarker parameters on a neotropical teleost fish namely Cnesterodon decemmaculatus. Water samples were taken in order to determine the river's physicochemical profile. An integrative approach was applied using a biomarker index. The bioassay involved the use of laboratory culture adult animals, acclimatized in moderately hard water (MHW) and fed ad libitum. A semi-static 96 h bioassay was conducted and the experimental groups were as follows: [1] river water (Rg); [2] river water + 2 mg/L Cd (RgCd); [3] MHW + 2 mg/L Cadmium (Cd), positive metal control; [4] MHW + 5 mg/L Cyclophosphamide (positive genotoxicity control -CP); [5] MWH, negative control (NC). At the end of the exposure time fishes were sectioned and the following biomarkers were determined: 1) condition factor rate (CF); 2) for the anterior section (A) (head): glutathione (GSH) and protein (Pr) content; 3) for the body midsection (M) (viscera): Pr, GSH, Glutathione-S-transferase (GST), catalase (CAT) and superoxide dismutase (SOD). Blood samples were also taken from the fish specimens to estimate the frequency of micronuclei (MN) as well as other nuclear abnormalities (NA). The physicochemical profile of the river water sample indicated high Copper concentrations. CAT and SOD activity and total Pr content did not show any significant changes. GST activity decreased in fish exposed to Rg, while GSH content decreased significantly for all treatments compared to controls in MHW. These results would seem to point to a reduction in cell defense capability as a result of the depletion antioxidants such as GSH. The NA frequency increased significantly in all treated groups while MN frequency was increased only in Cd and CP groups. Using some the biomarkers measured, a biomarker index was estimated which revealed that fish exposed to Rg were 90% affected or highly affected, while those exposed to RgCd were 80% and Cd 68% affected or highly affected. The obtained results indicate the usefulness of the use of a battery of variables by means of the biomarker index to analyze water quality. Fil: Ossana, Natalia Alejandra. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina Fil: Eissa, Bettina Lorena. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina Fil: Baudou, Federico Gastón. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina. Ministerio de Ciencia. Tecnología e Innovación Productiva. Agencia Nacional de Promoción Científica y Tecnológica; Argentina Fil: Castañé, Patricia Mónica. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas. Programa de Ecofisiología Aplicada; Argentina Fil: Soloneski, Sonia Maria Elsa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; Argentina Fil: Ferrari, Lucrecia. Universidad Nacional de Luján. Instituto de Ecología y Desarrollo Sustentable. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Ecología y Desarrollo Sustentable; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina |
description |
The aim of this paper is to assess the water quality to chemical pollution at Roggero Dam, the headwater of the Reconquista river, and to perform a Cadmium (Cd) contamination pulse simulation through a wide battery of biomarkers which included: genotoxicity and enzymatic biomarker parameters on a neotropical teleost fish namely Cnesterodon decemmaculatus. Water samples were taken in order to determine the river's physicochemical profile. An integrative approach was applied using a biomarker index. The bioassay involved the use of laboratory culture adult animals, acclimatized in moderately hard water (MHW) and fed ad libitum. A semi-static 96 h bioassay was conducted and the experimental groups were as follows: [1] river water (Rg); [2] river water + 2 mg/L Cd (RgCd); [3] MHW + 2 mg/L Cadmium (Cd), positive metal control; [4] MHW + 5 mg/L Cyclophosphamide (positive genotoxicity control -CP); [5] MWH, negative control (NC). At the end of the exposure time fishes were sectioned and the following biomarkers were determined: 1) condition factor rate (CF); 2) for the anterior section (A) (head): glutathione (GSH) and protein (Pr) content; 3) for the body midsection (M) (viscera): Pr, GSH, Glutathione-S-transferase (GST), catalase (CAT) and superoxide dismutase (SOD). Blood samples were also taken from the fish specimens to estimate the frequency of micronuclei (MN) as well as other nuclear abnormalities (NA). The physicochemical profile of the river water sample indicated high Copper concentrations. CAT and SOD activity and total Pr content did not show any significant changes. GST activity decreased in fish exposed to Rg, while GSH content decreased significantly for all treatments compared to controls in MHW. These results would seem to point to a reduction in cell defense capability as a result of the depletion antioxidants such as GSH. The NA frequency increased significantly in all treated groups while MN frequency was increased only in Cd and CP groups. Using some the biomarkers measured, a biomarker index was estimated which revealed that fish exposed to Rg were 90% affected or highly affected, while those exposed to RgCd were 80% and Cd 68% affected or highly affected. The obtained results indicate the usefulness of the use of a battery of variables by means of the biomarker index to analyze water quality. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-11 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/114765 Ossana, Natalia Alejandra; Eissa, Bettina Lorena; Baudou, Federico Gastón; Castañé, Patricia Mónica; Soloneski, Sonia Maria Elsa; et al.; Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water; Academic Press Inc Elsevier Science; Ecotoxicology and Environmental Safety; 133; 11-2016; 73-81 0147-6513 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/114765 |
identifier_str_mv |
Ossana, Natalia Alejandra; Eissa, Bettina Lorena; Baudou, Federico Gastón; Castañé, Patricia Mónica; Soloneski, Sonia Maria Elsa; et al.; Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water; Academic Press Inc Elsevier Science; Ecotoxicology and Environmental Safety; 133; 11-2016; 73-81 0147-6513 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0147651316302524 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ecoenv.2016.06.046 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Academic Press Inc Elsevier Science |
publisher.none.fl_str_mv |
Academic Press Inc Elsevier Science |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
_version_ |
1842269169658101760 |
score |
13.13397 |