WHF IASC Roadmap on Chagas Disease

• Autores: Echeverría, Luis Eduardo; Marcus, Rachel; Novick, Gabriel; Sosa-Estani, Sergio Alejandro; Ralston, Kate; Zaidel, Ezequiel Jose; Forsyth, Colin; RIbeiro, Antonio Luiz P.; Mendoza, Iván; Falconi, Mariano Luis; Mitelman, Jorge Eduardo; Morillo, Carlos A.; Pereiro, Ana Cristina; Pinazo, María Jesús; Salvatella, Roberto; Martinez, Felipe; Perel, Pablo; Sosa Liprandi, Álvaro; Piñeiro, Daniel José; Restrepo Molina, Gustavo
• Año de publicación: 2020
• Idioma: inglés
• Tipo de recurso: artículo
• Materia: CARDIOMYOPATHY; CHAGAS DISEASE; HEART FAILURE; NEGLECTED TROPICAL DISEASE
• Institución: Consejo Nacional de Investigaciones Científicas y Técnicas

Background: Chagas Disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi, with some of the most serious manifestations affecting the cardiovascular system. It is a chronic, stigmatizing condition, closely associated with poverty and affecting close to 6 million people globally. Although historically the disease was limited to endemic areas of Latin America recent years have seen an increasing global spread. In addition to the morbidity and mortality associated with the disease, the social and economic burdens on individuals and society are substantial. Often called the 'silent killer', Chagas disease is characterized by a long, asymptomatic phase in affected individuals. Approximately 30% then go on develop chronic Chagas cardiomyopathy and other serious cardiac complications such as stroke, rhythm disturbances and severe heart failure. Methods: In a collaboration of the World Hearth Federation (WHF) and the Inter-American Society of Cardiology (IASC) a writing group consisting of 20 diverse experts on Chagas disease (CD) was convened. The group provided up to date expert knowledge based on their area of expertise. An extensive review of the literature describing obstacles to diagnosis and treatment of CD along with proposed solutions was conducted. A survey was sent to all WHF Members and, using snowball sampling to widen the consultation, to a variety of health care professionals working in the CD global health community. The results were analyzed, open comments were reviewed and consolidated, and the findings were incorporated into this document, thus ensuring a consensus representation. Results: The WHF IASC Roadmap on Chagas Disease offers a comprehensive summary of current knowledge on prevention, diagnosis and management of the disease. In providing an analysis of 'roadblocks' in access to comprehensive care for Chagas disease patients, the document serves as a framework from which strategies for implementation such as national plans can be formulated. Several dimensions are considered in the analysis: healthcare system capabilities, governance, financing, community awareness and advocacy. Conclusion: The WHF IASC Roadmap proposes strategies and evidence-based solutions for healthcare professionals, health authorities and governments to help overcome the barriers to comprehensive care for Chagas disease patients. This roadmap describes an ideal patient care pathway, and explores the roadblocks along the way, offering potential solutions based on available research and examples in practice. It represents a call to action to decision-makers and health care professionals to step up efforts to eradicate Chagas disease.
Fil: Echeverría, Luis Eduardo. Cardiovascular Foundation Of Colombia; Colombia
Fil: Marcus, Rachel. Union Memorial Hospital; Estados Unidos
Fil: Novick, Gabriel. Tufts University; Estados Unidos
Fil: Sosa-Estani, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Ralston, Kate. World Heart Federation; Suiza
Fil: Zaidel, Ezequiel Jose. Universidad de Buenos Aires; Argentina
Fil: Forsyth, Colin. Drugs For Neglected Diseases Initiative; Estados Unidos
Fil: RIbeiro, Antonio Luiz P.. Universidade Federal de Minas Gerais; Brasil
Fil: Mendoza, Iván. Universidad Central de Venezuela; Venezuela
Fil: Falconi, Mariano Luis. Hospital Italiano; Argentina
Fil: Mitelman, Jorge Eduardo. Universidad de Buenos Aires; Argentina
Fil: Morillo, Carlos A.. University of Calgary; Canadá
Fil: Pereiro, Ana Cristina. Fundación Mundo Sano; Argentina
Fil: Pinazo, María Jesús. Universidad de Barcelona; España
Fil: Salvatella, Roberto. No especifíca;
Fil: Martinez, Felipe. Universidad Nacional de Córdoba; Argentina
Fil: Perel, Pablo. No especifíca;
Fil: Sosa Liprandi, Álvaro. Universidad de Buenos Aires; Argentina
Fil: Piñeiro, Daniel José. Universidad de Buenos Aires; Argentina
Fil: Restrepo Molina, Gustavo. Universidad Ces; Colombia