The relative importance to life of cortex and medulla of the adrenal glands

Autores
Houssay, Bernardo Alberto; Lewis, Juan Treharne
Año de publicación
1923
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The following facts are definitely established: I, Double adrenalectomy is fatal in most species, amongst them the dog. 2, Removal of all chromophil tissue contained in these glands is perfectly harmless. 3, Extirpation of inter-renal body (equivalent of cortex in Elasmobranchs) is followed by death. We may therefore conclude, I, The cortex is indispensable to life; it maintains its vital functions without the cooperation of the medulla. 2, The chromophil tissue of the suprarenals is not necessary to life or to normal functions. This does not mean that chromophil tissue is not indispensable to life. In our experiments only a part of this tissue is removed, and it must be remembered that relatively a greater portion of medullary tissue than of cortical tissue remains in the body after adrenalectomy. If chromophil tissue has vital functions, the extra-capsular portion is sufficient to maintain them, but up to now we have no evidence that these vital functions exist.
Fil: Houssay, Bernardo Alberto. Universidad de Buenos Aires; Argentina
Fil: Lewis, Juan Treharne. Universidad de Buenos Aires; Argentina
Unidad documental simple
Materia
HOUSSAY, BERNARDO A.
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
ADRENALECTOMY
DOGS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/125034
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/125034
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling The relative importance to life of cortex and medulla of the adrenal glandsHoussay, Bernardo AlbertoLewis, Juan TreharneHOUSSAY, BERNARDO A.EL INVESTIGADORHOUSSAY EL INVESTIGADORPUBLICACIONESADRENALECTOMYDOGShttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The following facts are definitely established: I, Double adrenalectomy is fatal in most species, amongst them the dog. 2, Removal of all chromophil tissue contained in these glands is perfectly harmless. 3, Extirpation of inter-renal body (equivalent of cortex in Elasmobranchs) is followed by death. We may therefore conclude, I, The cortex is indispensable to life; it maintains its vital functions without the cooperation of the medulla. 2, The chromophil tissue of the suprarenals is not necessary to life or to normal functions. This does not mean that chromophil tissue is not indispensable to life. In our experiments only a part of this tissue is removed, and it must be remembered that relatively a greater portion of medullary tissue than of cortical tissue remains in the body after adrenalectomy. If chromophil tissue has vital functions, the extra-capsular portion is sufficient to maintain them, but up to now we have no evidence that these vital functions exist.Fil: Houssay, Bernardo Alberto. Universidad de Buenos Aires; ArgentinaFil: Lewis, Juan Treharne. Universidad de Buenos Aires; ArgentinaUnidad documental simpleAmerican Physiological Society1923info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articulotext/plainEscalaGrisNoapplication/pdfhttp://hdl.handle.net/11336/125034Houssay, Bernardo Alberto; Lewis, Juan Treharne; The relative importance to life of cortex and medulla of the adrenal glands; American Physiological Society; American Journal of Physiology; 64; 3; 1923; 512-5210002-9513engCiudad de Buenos AiresFundacion Williams.Consejo Nacional de Investigaciones Científicas y TécnicasFundación de Instituto de Biología y Medicina ExperimentalProyecto Houssay y Leloirinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:15:52Zoai:ri.conicet.gov.ar:11336/125034instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:15:52.933CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The relative importance to life of cortex and medulla of the adrenal glands
title The relative importance to life of cortex and medulla of the adrenal glands
spellingShingle The relative importance to life of cortex and medulla of the adrenal glands
Houssay, Bernardo Alberto
HOUSSAY, BERNARDO A.
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
ADRENALECTOMY
DOGS
title_short The relative importance to life of cortex and medulla of the adrenal glands
title_full The relative importance to life of cortex and medulla of the adrenal glands
title_fullStr The relative importance to life of cortex and medulla of the adrenal glands
title_full_unstemmed The relative importance to life of cortex and medulla of the adrenal glands
title_sort The relative importance to life of cortex and medulla of the adrenal glands
dc.creator.none.fl_str_mv Houssay, Bernardo Alberto
Lewis, Juan Treharne
author Houssay, Bernardo Alberto
author_facet Houssay, Bernardo Alberto
Lewis, Juan Treharne
author_role author
author2 Lewis, Juan Treharne
author2_role author
dc.subject.none.fl_str_mv HOUSSAY, BERNARDO A.
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
ADRENALECTOMY
DOGS
topic HOUSSAY, BERNARDO A.
EL INVESTIGADOR
HOUSSAY EL INVESTIGADOR
PUBLICACIONES
ADRENALECTOMY
DOGS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The following facts are definitely established: I, Double adrenalectomy is fatal in most species, amongst them the dog. 2, Removal of all chromophil tissue contained in these glands is perfectly harmless. 3, Extirpation of inter-renal body (equivalent of cortex in Elasmobranchs) is followed by death. We may therefore conclude, I, The cortex is indispensable to life; it maintains its vital functions without the cooperation of the medulla. 2, The chromophil tissue of the suprarenals is not necessary to life or to normal functions. This does not mean that chromophil tissue is not indispensable to life. In our experiments only a part of this tissue is removed, and it must be remembered that relatively a greater portion of medullary tissue than of cortical tissue remains in the body after adrenalectomy. If chromophil tissue has vital functions, the extra-capsular portion is sufficient to maintain them, but up to now we have no evidence that these vital functions exist.
Fil: Houssay, Bernardo Alberto. Universidad de Buenos Aires; Argentina
Fil: Lewis, Juan Treharne. Universidad de Buenos Aires; Argentina
Unidad documental simple
description The following facts are definitely established: I, Double adrenalectomy is fatal in most species, amongst them the dog. 2, Removal of all chromophil tissue contained in these glands is perfectly harmless. 3, Extirpation of inter-renal body (equivalent of cortex in Elasmobranchs) is followed by death. We may therefore conclude, I, The cortex is indispensable to life; it maintains its vital functions without the cooperation of the medulla. 2, The chromophil tissue of the suprarenals is not necessary to life or to normal functions. This does not mean that chromophil tissue is not indispensable to life. In our experiments only a part of this tissue is removed, and it must be remembered that relatively a greater portion of medullary tissue than of cortical tissue remains in the body after adrenalectomy. If chromophil tissue has vital functions, the extra-capsular portion is sufficient to maintain them, but up to now we have no evidence that these vital functions exist.
publishDate 1923
dc.date.none.fl_str_mv 1923
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/125034
Houssay, Bernardo Alberto; Lewis, Juan Treharne; The relative importance to life of cortex and medulla of the adrenal glands; American Physiological Society; American Journal of Physiology; 64; 3; 1923; 512-521
0002-9513
url http://hdl.handle.net/11336/125034
identifier_str_mv Houssay, Bernardo Alberto; Lewis, Juan Treharne; The relative importance to life of cortex and medulla of the adrenal glands; American Physiological Society; American Journal of Physiology; 64; 3; 1923; 512-521
0002-9513
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ciudad de Buenos Aires
Fundacion Williams.
Consejo Nacional de Investigaciones Científicas y Técnicas
Fundación de Instituto de Biología y Medicina Experimental
Proyecto Houssay y Leloir
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv text/plain
EscalaGris
No
application/pdf
dc.publisher.none.fl_str_mv American Physiological Society
publisher.none.fl_str_mv American Physiological Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842980859626389504
score 12.993085

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