A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease

Autores
Fernández, Gerardo Abel; Schumacher, Marcela Silvana; Orozco, David; Sgrilli, Gustavo; Echeverria, Gustavo; Linares, Ramiro; Parra, Mario A.
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Recent evidence suggests that oculomotor behaviours linked to cognitive performance can be a biomarker of Alzheimer’s disease (AD). Short-Term Memory Binding (STMB) declines in patients with AD dementia and in those at risk of dementia. STMB relies on brain regions relevant to visual processing which are known to support oculomotor behaviours. Viewmind is proposed as a novel “cognitive digital biomarker” with the potential of revealing phenotypic features of AD in the pre-dementia stage of the pathology. Viewmind applies artificial intelligence to analyse eye movements and pupil responses during the performance of STMBT.
Fil: Fernández, Gerardo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages". Universidad Nacional del Sur. Departamento de Ingeniería Eléctrica y de Computadoras. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages"; Argentina
Fil: Schumacher, Marcela Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages". Universidad Nacional del Sur. Departamento de Ingeniería Eléctrica y de Computadoras. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages"; Argentina
Fil: Orozco, David. Axis Neurociencias; Argentina
Fil: Sgrilli, Gustavo. Axis Neurociencias; Argentina
Fil: Echeverria, Gustavo. Axis Neurociencias; Argentina
Fil: Linares, Ramiro. Axis Neurociencias; Argentina
Fil: Parra, Mario A.. Strathclyde University; Reino Unido
Materia
ALZHEIMER
BIOMARKER
COGNITIVE BIOMARKER
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/197894
Acceder
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network_name_str CONICET Digital (CONICET)
spelling A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s diseaseFernández, Gerardo AbelSchumacher, Marcela SilvanaOrozco, DavidSgrilli, GustavoEcheverria, GustavoLinares, RamiroParra, Mario A.ALZHEIMERBIOMARKERCOGNITIVE BIOMARKERhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Recent evidence suggests that oculomotor behaviours linked to cognitive performance can be a biomarker of Alzheimer’s disease (AD). Short-Term Memory Binding (STMB) declines in patients with AD dementia and in those at risk of dementia. STMB relies on brain regions relevant to visual processing which are known to support oculomotor behaviours. Viewmind is proposed as a novel “cognitive digital biomarker” with the potential of revealing phenotypic features of AD in the pre-dementia stage of the pathology. Viewmind applies artificial intelligence to analyse eye movements and pupil responses during the performance of STMBT.Fil: Fernández, Gerardo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages". Universidad Nacional del Sur. Departamento de Ingeniería Eléctrica y de Computadoras. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages"; ArgentinaFil: Schumacher, Marcela Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages". Universidad Nacional del Sur. Departamento de Ingeniería Eléctrica y de Computadoras. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages"; ArgentinaFil: Orozco, David. Axis Neurociencias; ArgentinaFil: Sgrilli, Gustavo. Axis Neurociencias; ArgentinaFil: Echeverria, Gustavo. Axis Neurociencias; ArgentinaFil: Linares, Ramiro. Axis Neurociencias; ArgentinaFil: Parra, Mario A.. Strathclyde University; Reino UnidoElsevier Science Inc.2021-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/197894Fernández, Gerardo Abel; Schumacher, Marcela Silvana; Orozco, David; Sgrilli, Gustavo; Echeverria, Gustavo; et al.; A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease; Elsevier Science Inc.; Alzheimers & Dementia; 17; S5; 12-2021; 1-21552-5260CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1002/alz.055018info:eu-repo/semantics/altIdentifier/doi/10.1002/alz.055018info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:11:20Zoai:ri.conicet.gov.ar:11336/197894instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:11:21.097CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
title A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
spellingShingle A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
Fernández, Gerardo Abel
ALZHEIMER
BIOMARKER
COGNITIVE BIOMARKER
title_short A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
title_full A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
title_fullStr A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
title_full_unstemmed A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
title_sort A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease
dc.creator.none.fl_str_mv Fernández, Gerardo Abel
Schumacher, Marcela Silvana
Orozco, David
Sgrilli, Gustavo
Echeverria, Gustavo
Linares, Ramiro
Parra, Mario A.
author Fernández, Gerardo Abel
author_facet Fernández, Gerardo Abel
Schumacher, Marcela Silvana
Orozco, David
Sgrilli, Gustavo
Echeverria, Gustavo
Linares, Ramiro
Parra, Mario A.
author_role author
author2 Schumacher, Marcela Silvana
Orozco, David
Sgrilli, Gustavo
Echeverria, Gustavo
Linares, Ramiro
Parra, Mario A.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ALZHEIMER
BIOMARKER
COGNITIVE BIOMARKER
topic ALZHEIMER
BIOMARKER
COGNITIVE BIOMARKER
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Recent evidence suggests that oculomotor behaviours linked to cognitive performance can be a biomarker of Alzheimer’s disease (AD). Short-Term Memory Binding (STMB) declines in patients with AD dementia and in those at risk of dementia. STMB relies on brain regions relevant to visual processing which are known to support oculomotor behaviours. Viewmind is proposed as a novel “cognitive digital biomarker” with the potential of revealing phenotypic features of AD in the pre-dementia stage of the pathology. Viewmind applies artificial intelligence to analyse eye movements and pupil responses during the performance of STMBT.
Fil: Fernández, Gerardo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages". Universidad Nacional del Sur. Departamento de Ingeniería Eléctrica y de Computadoras. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages"; Argentina
Fil: Schumacher, Marcela Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages". Universidad Nacional del Sur. Departamento de Ingeniería Eléctrica y de Computadoras. Instituto de Investigaciones en Ingeniería Eléctrica "Alfredo Desages"; Argentina
Fil: Orozco, David. Axis Neurociencias; Argentina
Fil: Sgrilli, Gustavo. Axis Neurociencias; Argentina
Fil: Echeverria, Gustavo. Axis Neurociencias; Argentina
Fil: Linares, Ramiro. Axis Neurociencias; Argentina
Fil: Parra, Mario A.. Strathclyde University; Reino Unido
description Recent evidence suggests that oculomotor behaviours linked to cognitive performance can be a biomarker of Alzheimer’s disease (AD). Short-Term Memory Binding (STMB) declines in patients with AD dementia and in those at risk of dementia. STMB relies on brain regions relevant to visual processing which are known to support oculomotor behaviours. Viewmind is proposed as a novel “cognitive digital biomarker” with the potential of revealing phenotypic features of AD in the pre-dementia stage of the pathology. Viewmind applies artificial intelligence to analyse eye movements and pupil responses during the performance of STMBT.
publishDate 2021
dc.date.none.fl_str_mv 2021-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/197894
Fernández, Gerardo Abel; Schumacher, Marcela Silvana; Orozco, David; Sgrilli, Gustavo; Echeverria, Gustavo; et al.; A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease; Elsevier Science Inc.; Alzheimers & Dementia; 17; S5; 12-2021; 1-2
1552-5260
CONICET Digital
CONICET
url http://hdl.handle.net/11336/197894
identifier_str_mv Fernández, Gerardo Abel; Schumacher, Marcela Silvana; Orozco, David; Sgrilli, Gustavo; Echeverria, Gustavo; et al.; A novel digital cognitive biomarker for mild cognitive impairment and Alzheimer’s disease; Elsevier Science Inc.; Alzheimers & Dementia; 17; S5; 12-2021; 1-2
1552-5260
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1002/alz.055018
info:eu-repo/semantics/altIdentifier/doi/10.1002/alz.055018
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science Inc.
publisher.none.fl_str_mv Elsevier Science Inc.
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842270154437689344
score 13.13397

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