Participation of Rabs during Neuronal Development and Disease

Autores
Rozés Salvador, María Victoria; Conde, Cecilia Beatriz
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Membrane traffic has been widely studied in recent decades, and now it is clear that its participation in biologicalprocesses such as cellular migration, mitosis, and immune response, among others, is crucial and determinant.During the development of the nervous system, membrane trafficking organizes both the differential distributionand degradation of specific components, among others. Failures in these functions lead to the development ofneurological pathologies that can be progressive, chronic or even lethal such as Alzheimer´s, Huntington´s andParkinson´s diseases. These pathologies have significant health and economic costs in many countries. For thisreason, research is being focused on the study of those components (mainly proteins) involved in membrane trafficduring health and disease. In this short communication, we summarize main findings and state of the art discussionabout the functions of some membrane trafficking components during development, as well as the implications oftheir dysfunction into the progression of neurological pathologies.
Fil: Rozés Salvador, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Conde, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Materia
MEMBRANE TRAFFICKING
RABS
NEURONAL DEVELOPMENT
NEURONAL DISEASES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/128757
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Participation of Rabs during Neuronal Development and DiseaseRozés Salvador, María VictoriaConde, Cecilia BeatrizMEMBRANE TRAFFICKINGRABSNEURONAL DEVELOPMENTNEURONAL DISEASEShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Membrane traffic has been widely studied in recent decades, and now it is clear that its participation in biologicalprocesses such as cellular migration, mitosis, and immune response, among others, is crucial and determinant.During the development of the nervous system, membrane trafficking organizes both the differential distributionand degradation of specific components, among others. Failures in these functions lead to the development ofneurological pathologies that can be progressive, chronic or even lethal such as Alzheimer´s, Huntington´s andParkinson´s diseases. These pathologies have significant health and economic costs in many countries. For thisreason, research is being focused on the study of those components (mainly proteins) involved in membrane trafficduring health and disease. In this short communication, we summarize main findings and state of the art discussionabout the functions of some membrane trafficking components during development, as well as the implications oftheir dysfunction into the progression of neurological pathologies.Fil: Rozés Salvador, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Conde, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaOMICS International2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/128757Rozés Salvador, María Victoria; Conde, Cecilia Beatriz; Participation of Rabs during Neuronal Development and Disease; OMICS International; Journal of Molecular and Genetic Medicine; 13; 1; 2019; 1-31747-0862CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.4172/1747-0862.1000397info:eu-repo/semantics/altIdentifier/url/https://www.hilarispublisher.com/abstract/participation-of-rabs-during-neuronal-development-and-disease-38081.htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:03:10Zoai:ri.conicet.gov.ar:11336/128757instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:03:10.429CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Participation of Rabs during Neuronal Development and Disease
title Participation of Rabs during Neuronal Development and Disease
spellingShingle Participation of Rabs during Neuronal Development and Disease
Rozés Salvador, María Victoria
MEMBRANE TRAFFICKING
RABS
NEURONAL DEVELOPMENT
NEURONAL DISEASES
title_short Participation of Rabs during Neuronal Development and Disease
title_full Participation of Rabs during Neuronal Development and Disease
title_fullStr Participation of Rabs during Neuronal Development and Disease
title_full_unstemmed Participation of Rabs during Neuronal Development and Disease
title_sort Participation of Rabs during Neuronal Development and Disease
dc.creator.none.fl_str_mv Rozés Salvador, María Victoria
Conde, Cecilia Beatriz
author Rozés Salvador, María Victoria
author_facet Rozés Salvador, María Victoria
Conde, Cecilia Beatriz
author_role author
author2 Conde, Cecilia Beatriz
author2_role author
dc.subject.none.fl_str_mv MEMBRANE TRAFFICKING
RABS
NEURONAL DEVELOPMENT
NEURONAL DISEASES
topic MEMBRANE TRAFFICKING
RABS
NEURONAL DEVELOPMENT
NEURONAL DISEASES
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Membrane traffic has been widely studied in recent decades, and now it is clear that its participation in biologicalprocesses such as cellular migration, mitosis, and immune response, among others, is crucial and determinant.During the development of the nervous system, membrane trafficking organizes both the differential distributionand degradation of specific components, among others. Failures in these functions lead to the development ofneurological pathologies that can be progressive, chronic or even lethal such as Alzheimer´s, Huntington´s andParkinson´s diseases. These pathologies have significant health and economic costs in many countries. For thisreason, research is being focused on the study of those components (mainly proteins) involved in membrane trafficduring health and disease. In this short communication, we summarize main findings and state of the art discussionabout the functions of some membrane trafficking components during development, as well as the implications oftheir dysfunction into the progression of neurological pathologies.
Fil: Rozés Salvador, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
Fil: Conde, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
description Membrane traffic has been widely studied in recent decades, and now it is clear that its participation in biologicalprocesses such as cellular migration, mitosis, and immune response, among others, is crucial and determinant.During the development of the nervous system, membrane trafficking organizes both the differential distributionand degradation of specific components, among others. Failures in these functions lead to the development ofneurological pathologies that can be progressive, chronic or even lethal such as Alzheimer´s, Huntington´s andParkinson´s diseases. These pathologies have significant health and economic costs in many countries. For thisreason, research is being focused on the study of those components (mainly proteins) involved in membrane trafficduring health and disease. In this short communication, we summarize main findings and state of the art discussionabout the functions of some membrane trafficking components during development, as well as the implications oftheir dysfunction into the progression of neurological pathologies.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/128757
Rozés Salvador, María Victoria; Conde, Cecilia Beatriz; Participation of Rabs during Neuronal Development and Disease; OMICS International; Journal of Molecular and Genetic Medicine; 13; 1; 2019; 1-3
1747-0862
CONICET Digital
CONICET
url http://hdl.handle.net/11336/128757
identifier_str_mv Rozés Salvador, María Victoria; Conde, Cecilia Beatriz; Participation of Rabs during Neuronal Development and Disease; OMICS International; Journal of Molecular and Genetic Medicine; 13; 1; 2019; 1-3
1747-0862
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.4172/1747-0862.1000397
info:eu-repo/semantics/altIdentifier/url/https://www.hilarispublisher.com/abstract/participation-of-rabs-during-neuronal-development-and-disease-38081.html
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv OMICS International
publisher.none.fl_str_mv OMICS International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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