Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology

Autores
Islam, Md Aminul; Sharmin, Aqter Rony; Rahman, Mohammad Bozlur; Cinar, Mehmet Ulas; Villena, Julio Cesar; Uddin, Muhammad Jasim; Kitazawa, Haruki
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Disease occurrence adversely affects livestock production and animal welfare, and havean impact on both human health and public perception of food-animals production. Combinedefforts from farmers, animal scientists, and veterinarians have been continuing to explore theeffective disease control approaches for the production of safe animal-originated food. Implementing the immunogenomics, along with genome editing technology, has been considering as the key approach for safe food-animal production through the improvement of the host genetic resistance. Next-generation sequencing, as a cutting-edge technique, enables the production of high throughput transcriptomic and genomic profiles resulted from host-pathogen interactions. Immunogenomics combine the transcriptomic and genomic data that links to host resistance to disease, and predict the potential candidate genes and their genomic locations. Genome editing, which involves insertion, deletion, or modification of one or more genes in the DNA sequence, is advancing rapidly and may be poised to become a commercial reality faster than it has thought. The clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) [CRISPR/Cas9] system has recently emerged as a powerful tool for genome editing in agricultural food production including livestock disease management. CRISPR/Cas9 mediated insertion of NRAMP1 gene for producing tuberculosis resistant cattle, and deletion of CD163 gene for producing porcine reproductive and respiratory syndrome (PRRS) resistant pigs are two groundbreaking applications of genome editing in livestock. In this review, we have highlighted the technological advances of livestock immunogenomics and the principles and scopes of application of CRISPR/Cas9-mediated targeted genome editing in animal breeding for disease resistance.
Fil: Islam, Md Aminul. Tohoku University; Japón. Bangladesh Agricultural University; Bangladesh
Fil: Sharmin, Aqter Rony. Bangladesh Agricultural University; Bangladesh
Fil: Rahman, Mohammad Bozlur. Department of Livestock Services; Bangladesh
Fil: Cinar, Mehmet Ulas. Erciyes University; Turquía. Washington State University; Estados Unidos
Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Tohoku University; Japón
Fil: Uddin, Muhammad Jasim. Bangladesh Agricultural University; Bangladesh. University of Queensland; Australia
Fil: Kitazawa, Haruki. Tohoku University; Japón
Materia
NEXT GENERATION SEQUENCING
DISEASE RESISTANCE
TRANSCRIPTOMICS
BIOINFORMATICS
GENOME EDITING
LIVESTOCK
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/138223

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network_name_str CONICET Digital (CONICET)
spelling Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technologyIslam, Md AminulSharmin, Aqter RonyRahman, Mohammad BozlurCinar, Mehmet UlasVillena, Julio CesarUddin, Muhammad JasimKitazawa, HarukiNEXT GENERATION SEQUENCINGDISEASE RESISTANCETRANSCRIPTOMICSBIOINFORMATICSGENOME EDITINGLIVESTOCKhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Disease occurrence adversely affects livestock production and animal welfare, and havean impact on both human health and public perception of food-animals production. Combinedefforts from farmers, animal scientists, and veterinarians have been continuing to explore theeffective disease control approaches for the production of safe animal-originated food. Implementing the immunogenomics, along with genome editing technology, has been considering as the key approach for safe food-animal production through the improvement of the host genetic resistance. Next-generation sequencing, as a cutting-edge technique, enables the production of high throughput transcriptomic and genomic profiles resulted from host-pathogen interactions. Immunogenomics combine the transcriptomic and genomic data that links to host resistance to disease, and predict the potential candidate genes and their genomic locations. Genome editing, which involves insertion, deletion, or modification of one or more genes in the DNA sequence, is advancing rapidly and may be poised to become a commercial reality faster than it has thought. The clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) [CRISPR/Cas9] system has recently emerged as a powerful tool for genome editing in agricultural food production including livestock disease management. CRISPR/Cas9 mediated insertion of NRAMP1 gene for producing tuberculosis resistant cattle, and deletion of CD163 gene for producing porcine reproductive and respiratory syndrome (PRRS) resistant pigs are two groundbreaking applications of genome editing in livestock. In this review, we have highlighted the technological advances of livestock immunogenomics and the principles and scopes of application of CRISPR/Cas9-mediated targeted genome editing in animal breeding for disease resistance.Fil: Islam, Md Aminul. Tohoku University; Japón. Bangladesh Agricultural University; BangladeshFil: Sharmin, Aqter Rony. Bangladesh Agricultural University; BangladeshFil: Rahman, Mohammad Bozlur. Department of Livestock Services; BangladeshFil: Cinar, Mehmet Ulas. Erciyes University; Turquía. Washington State University; Estados UnidosFil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Tohoku University; JapónFil: Uddin, Muhammad Jasim. Bangladesh Agricultural University; Bangladesh. University of Queensland; AustraliaFil: Kitazawa, Haruki. Tohoku University; JapónMolecular Diversity Preservation International2020-11-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/138223Islam, Md Aminul; Sharmin, Aqter Rony; Rahman, Mohammad Bozlur; Cinar, Mehmet Ulas; Villena, Julio Cesar; et al.; Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology; Molecular Diversity Preservation International; Animals; 10; 12; 28-11-2020; 1-202076-26152076-2615CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/ani10122236info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-2615/10/12/2236info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:54:51Zoai:ri.conicet.gov.ar:11336/138223instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:54:51.842CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
title Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
spellingShingle Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
Islam, Md Aminul
NEXT GENERATION SEQUENCING
DISEASE RESISTANCE
TRANSCRIPTOMICS
BIOINFORMATICS
GENOME EDITING
LIVESTOCK
title_short Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
title_full Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
title_fullStr Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
title_full_unstemmed Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
title_sort Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology
dc.creator.none.fl_str_mv Islam, Md Aminul
Sharmin, Aqter Rony
Rahman, Mohammad Bozlur
Cinar, Mehmet Ulas
Villena, Julio Cesar
Uddin, Muhammad Jasim
Kitazawa, Haruki
author Islam, Md Aminul
author_facet Islam, Md Aminul
Sharmin, Aqter Rony
Rahman, Mohammad Bozlur
Cinar, Mehmet Ulas
Villena, Julio Cesar
Uddin, Muhammad Jasim
Kitazawa, Haruki
author_role author
author2 Sharmin, Aqter Rony
Rahman, Mohammad Bozlur
Cinar, Mehmet Ulas
Villena, Julio Cesar
Uddin, Muhammad Jasim
Kitazawa, Haruki
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv NEXT GENERATION SEQUENCING
DISEASE RESISTANCE
TRANSCRIPTOMICS
BIOINFORMATICS
GENOME EDITING
LIVESTOCK
topic NEXT GENERATION SEQUENCING
DISEASE RESISTANCE
TRANSCRIPTOMICS
BIOINFORMATICS
GENOME EDITING
LIVESTOCK
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Disease occurrence adversely affects livestock production and animal welfare, and havean impact on both human health and public perception of food-animals production. Combinedefforts from farmers, animal scientists, and veterinarians have been continuing to explore theeffective disease control approaches for the production of safe animal-originated food. Implementing the immunogenomics, along with genome editing technology, has been considering as the key approach for safe food-animal production through the improvement of the host genetic resistance. Next-generation sequencing, as a cutting-edge technique, enables the production of high throughput transcriptomic and genomic profiles resulted from host-pathogen interactions. Immunogenomics combine the transcriptomic and genomic data that links to host resistance to disease, and predict the potential candidate genes and their genomic locations. Genome editing, which involves insertion, deletion, or modification of one or more genes in the DNA sequence, is advancing rapidly and may be poised to become a commercial reality faster than it has thought. The clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) [CRISPR/Cas9] system has recently emerged as a powerful tool for genome editing in agricultural food production including livestock disease management. CRISPR/Cas9 mediated insertion of NRAMP1 gene for producing tuberculosis resistant cattle, and deletion of CD163 gene for producing porcine reproductive and respiratory syndrome (PRRS) resistant pigs are two groundbreaking applications of genome editing in livestock. In this review, we have highlighted the technological advances of livestock immunogenomics and the principles and scopes of application of CRISPR/Cas9-mediated targeted genome editing in animal breeding for disease resistance.
Fil: Islam, Md Aminul. Tohoku University; Japón. Bangladesh Agricultural University; Bangladesh
Fil: Sharmin, Aqter Rony. Bangladesh Agricultural University; Bangladesh
Fil: Rahman, Mohammad Bozlur. Department of Livestock Services; Bangladesh
Fil: Cinar, Mehmet Ulas. Erciyes University; Turquía. Washington State University; Estados Unidos
Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Tohoku University; Japón
Fil: Uddin, Muhammad Jasim. Bangladesh Agricultural University; Bangladesh. University of Queensland; Australia
Fil: Kitazawa, Haruki. Tohoku University; Japón
description Disease occurrence adversely affects livestock production and animal welfare, and havean impact on both human health and public perception of food-animals production. Combinedefforts from farmers, animal scientists, and veterinarians have been continuing to explore theeffective disease control approaches for the production of safe animal-originated food. Implementing the immunogenomics, along with genome editing technology, has been considering as the key approach for safe food-animal production through the improvement of the host genetic resistance. Next-generation sequencing, as a cutting-edge technique, enables the production of high throughput transcriptomic and genomic profiles resulted from host-pathogen interactions. Immunogenomics combine the transcriptomic and genomic data that links to host resistance to disease, and predict the potential candidate genes and their genomic locations. Genome editing, which involves insertion, deletion, or modification of one or more genes in the DNA sequence, is advancing rapidly and may be poised to become a commercial reality faster than it has thought. The clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) [CRISPR/Cas9] system has recently emerged as a powerful tool for genome editing in agricultural food production including livestock disease management. CRISPR/Cas9 mediated insertion of NRAMP1 gene for producing tuberculosis resistant cattle, and deletion of CD163 gene for producing porcine reproductive and respiratory syndrome (PRRS) resistant pigs are two groundbreaking applications of genome editing in livestock. In this review, we have highlighted the technological advances of livestock immunogenomics and the principles and scopes of application of CRISPR/Cas9-mediated targeted genome editing in animal breeding for disease resistance.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-28
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/138223
Islam, Md Aminul; Sharmin, Aqter Rony; Rahman, Mohammad Bozlur; Cinar, Mehmet Ulas; Villena, Julio Cesar; et al.; Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology; Molecular Diversity Preservation International; Animals; 10; 12; 28-11-2020; 1-20
2076-2615
2076-2615
CONICET Digital
CONICET
url http://hdl.handle.net/11336/138223
identifier_str_mv Islam, Md Aminul; Sharmin, Aqter Rony; Rahman, Mohammad Bozlur; Cinar, Mehmet Ulas; Villena, Julio Cesar; et al.; Improvement of disease resistance in livestock: application of immunogenomics and CRISPR/Cas9 technology; Molecular Diversity Preservation International; Animals; 10; 12; 28-11-2020; 1-20
2076-2615
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/ani10122236
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-2615/10/12/2236
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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