Brief commentary

Autores
Schattner, Mirta Ana; Lazzari, María Ángela
Año de publicación
2002
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Recently, Tibbles et al. [1] reported that thrombopoietin (TPO) was capable of inducing P-selectin expression independently of calcium movements or platelet aggregation. They also found that leukocyte– platelet aggregates occurred after TPO cell stimulation most probably mediated by P-selection expression. Although they stated that they described a novel role for TPO in platelet function and platelet–leukocyte interactions both activities have been previously described by severalgroups [2–6]. Most of the studies showed that although TPO was not able to induce platelet activation alone it synergized platelet responses, including P-selectin expression, triggered by different agonists.
Fil: Schattner, Mirta Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Lazzari, María Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Materia
Tpo
Leukocyte
Agonists
Platelets
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/55307
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Brief commentarySchattner, Mirta AnaLazzari, María ÁngelaTpoLeukocyteAgonistsPlateletshttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Recently, Tibbles et al. [1] reported that thrombopoietin (TPO) was capable of inducing P-selectin expression independently of calcium movements or platelet aggregation. They also found that leukocyte– platelet aggregates occurred after TPO cell stimulation most probably mediated by P-selection expression. Although they stated that they described a novel role for TPO in platelet function and platelet–leukocyte interactions both activities have been previously described by severalgroups [2–6]. Most of the studies showed that although TPO was not able to induce platelet activation alone it synergized platelet responses, including P-selectin expression, triggered by different agonists.Fil: Schattner, Mirta Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Lazzari, María Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaAcademic Press Inc Elsevier Science2002-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/55307Schattner, Mirta Ana; Lazzari, María Ángela; Brief commentary; Academic Press Inc Elsevier Science; Biochemical and Biophysical Research Communications; 299; 3; 12-2002; 343-3430006-291XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0006291X02026414info:eu-repo/semantics/altIdentifier/doi/10.1016/S0006-291X(02)02641-4info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-12T09:34:06Zoai:ri.conicet.gov.ar:11336/55307instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-12 09:34:07.29CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Brief commentary
title Brief commentary
spellingShingle Brief commentary
Schattner, Mirta Ana
Tpo
Leukocyte
Agonists
Platelets
title_short Brief commentary
title_full Brief commentary
title_fullStr Brief commentary
title_full_unstemmed Brief commentary
title_sort Brief commentary
dc.creator.none.fl_str_mv Schattner, Mirta Ana
Lazzari, María Ángela
author Schattner, Mirta Ana
author_facet Schattner, Mirta Ana
Lazzari, María Ángela
author_role author
author2 Lazzari, María Ángela
author2_role author
dc.subject.none.fl_str_mv Tpo
Leukocyte
Agonists
Platelets
topic Tpo
Leukocyte
Agonists
Platelets
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Recently, Tibbles et al. [1] reported that thrombopoietin (TPO) was capable of inducing P-selectin expression independently of calcium movements or platelet aggregation. They also found that leukocyte– platelet aggregates occurred after TPO cell stimulation most probably mediated by P-selection expression. Although they stated that they described a novel role for TPO in platelet function and platelet–leukocyte interactions both activities have been previously described by severalgroups [2–6]. Most of the studies showed that although TPO was not able to induce platelet activation alone it synergized platelet responses, including P-selectin expression, triggered by different agonists.
Fil: Schattner, Mirta Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
Fil: Lazzari, María Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
description Recently, Tibbles et al. [1] reported that thrombopoietin (TPO) was capable of inducing P-selectin expression independently of calcium movements or platelet aggregation. They also found that leukocyte– platelet aggregates occurred after TPO cell stimulation most probably mediated by P-selection expression. Although they stated that they described a novel role for TPO in platelet function and platelet–leukocyte interactions both activities have been previously described by severalgroups [2–6]. Most of the studies showed that although TPO was not able to induce platelet activation alone it synergized platelet responses, including P-selectin expression, triggered by different agonists.
publishDate 2002
dc.date.none.fl_str_mv 2002-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/55307
Schattner, Mirta Ana; Lazzari, María Ángela; Brief commentary; Academic Press Inc Elsevier Science; Biochemical and Biophysical Research Communications; 299; 3; 12-2002; 343-343
0006-291X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/55307
identifier_str_mv Schattner, Mirta Ana; Lazzari, María Ángela; Brief commentary; Academic Press Inc Elsevier Science; Biochemical and Biophysical Research Communications; 299; 3; 12-2002; 343-343
0006-291X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0006291X02026414
info:eu-repo/semantics/altIdentifier/doi/10.1016/S0006-291X(02)02641-4
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Academic Press Inc Elsevier Science
publisher.none.fl_str_mv Academic Press Inc Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1848597101639892992
score 13.142177

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