Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA

Autores
Buceta, David; Busto, Natalia; Barone, Giampaolo; Leal, José M.; Domínguez, Fernando; Giovanetti, Lisandro Jose; Requejo, Felix Gregorio; García, Begoña; López-Quintela, M. Arturo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Subnanometric samples, containing exclusively Ag2 and Ag3 clusters, were synthesized for the first time by kinetic control using an electrochemical technique without the use of surfactants or capping agents. By combination of thermodynamic and kinetic measurements and theoretical calculations, we show herein that Ag3 clusters interact with DNA through intercalation, inducing significant structural distortion to the DNA. The lifetime of Ag3 clusters in the intercalated position is two to three orders of magnitude longer than for classical organic intercalators, such as ethidium bromide or proflavine.
Fil: Buceta, David. Universidad de Santiago de Compostela; España
Fil: Busto, Natalia. Universidad de Burgos; España
Fil: Barone, Giampaolo. Università di Palermo; Italia
Fil: Leal, José M.. Universidad de Burgos; España
Fil: Domínguez, Fernando. Universidad de Santiago de Compostela; España
Fil: Giovanetti, Lisandro Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de la Plata; Argentina
Fil: Requejo, Felix Gregorio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de la Plata; Argentina
Fil: García, Begoña. Universidad de Burgos; España
Fil: López-Quintela, M. Arturo. Universidad de Santiago de Compostela; España
Materia
Clusters
Dna
Xanes
Kinetic Control
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/5078
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/5078
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNABuceta, DavidBusto, NataliaBarone, GiampaoloLeal, José M.Domínguez, FernandoGiovanetti, Lisandro JoseRequejo, Felix GregorioGarcía, BegoñaLópez-Quintela, M. ArturoClustersDnaXanesKinetic Controlhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Subnanometric samples, containing exclusively Ag2 and Ag3 clusters, were synthesized for the first time by kinetic control using an electrochemical technique without the use of surfactants or capping agents. By combination of thermodynamic and kinetic measurements and theoretical calculations, we show herein that Ag3 clusters interact with DNA through intercalation, inducing significant structural distortion to the DNA. The lifetime of Ag3 clusters in the intercalated position is two to three orders of magnitude longer than for classical organic intercalators, such as ethidium bromide or proflavine.Fil: Buceta, David. Universidad de Santiago de Compostela; EspañaFil: Busto, Natalia. Universidad de Burgos; EspañaFil: Barone, Giampaolo. Università di Palermo; ItaliaFil: Leal, José M.. Universidad de Burgos; EspañaFil: Domínguez, Fernando. Universidad de Santiago de Compostela; EspañaFil: Giovanetti, Lisandro Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de la Plata; ArgentinaFil: Requejo, Felix Gregorio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de la Plata; ArgentinaFil: García, Begoña. Universidad de Burgos; EspañaFil: López-Quintela, M. Arturo. Universidad de Santiago de Compostela; EspañaWiley2015-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/5078Buceta, David; Busto, Natalia; Barone, Giampaolo; Leal, José M.; Domínguez, Fernando; et al.; Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA; Wiley; Angewandte Chemie; 54; 26; 5-2015; 7612-76161433-7851enginfo:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/doi/10.1002/anie.201502917info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/anie.201502917/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-17T11:55:02Zoai:ri.conicet.gov.ar:11336/5078instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-17 11:55:03.246CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
title Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
spellingShingle Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
Buceta, David
Clusters
Dna
Xanes
Kinetic Control
title_short Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
title_full Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
title_fullStr Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
title_full_unstemmed Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
title_sort Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA
dc.creator.none.fl_str_mv Buceta, David
Busto, Natalia
Barone, Giampaolo
Leal, José M.
Domínguez, Fernando
Giovanetti, Lisandro Jose
Requejo, Felix Gregorio
García, Begoña
López-Quintela, M. Arturo
author Buceta, David
author_facet Buceta, David
Busto, Natalia
Barone, Giampaolo
Leal, José M.
Domínguez, Fernando
Giovanetti, Lisandro Jose
Requejo, Felix Gregorio
García, Begoña
López-Quintela, M. Arturo
author_role author
author2 Busto, Natalia
Barone, Giampaolo
Leal, José M.
Domínguez, Fernando
Giovanetti, Lisandro Jose
Requejo, Felix Gregorio
García, Begoña
López-Quintela, M. Arturo
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Clusters
Dna
Xanes
Kinetic Control
topic Clusters
Dna
Xanes
Kinetic Control
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Subnanometric samples, containing exclusively Ag2 and Ag3 clusters, were synthesized for the first time by kinetic control using an electrochemical technique without the use of surfactants or capping agents. By combination of thermodynamic and kinetic measurements and theoretical calculations, we show herein that Ag3 clusters interact with DNA through intercalation, inducing significant structural distortion to the DNA. The lifetime of Ag3 clusters in the intercalated position is two to three orders of magnitude longer than for classical organic intercalators, such as ethidium bromide or proflavine.
Fil: Buceta, David. Universidad de Santiago de Compostela; España
Fil: Busto, Natalia. Universidad de Burgos; España
Fil: Barone, Giampaolo. Università di Palermo; Italia
Fil: Leal, José M.. Universidad de Burgos; España
Fil: Domínguez, Fernando. Universidad de Santiago de Compostela; España
Fil: Giovanetti, Lisandro Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de la Plata; Argentina
Fil: Requejo, Felix Gregorio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico la Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Universidad Nacional de la Plata; Argentina
Fil: García, Begoña. Universidad de Burgos; España
Fil: López-Quintela, M. Arturo. Universidad de Santiago de Compostela; España
description Subnanometric samples, containing exclusively Ag2 and Ag3 clusters, were synthesized for the first time by kinetic control using an electrochemical technique without the use of surfactants or capping agents. By combination of thermodynamic and kinetic measurements and theoretical calculations, we show herein that Ag3 clusters interact with DNA through intercalation, inducing significant structural distortion to the DNA. The lifetime of Ag3 clusters in the intercalated position is two to three orders of magnitude longer than for classical organic intercalators, such as ethidium bromide or proflavine.
publishDate 2015
dc.date.none.fl_str_mv 2015-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/5078
Buceta, David; Busto, Natalia; Barone, Giampaolo; Leal, José M.; Domínguez, Fernando; et al.; Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA; Wiley; Angewandte Chemie; 54; 26; 5-2015; 7612-7616
1433-7851
url http://hdl.handle.net/11336/5078
identifier_str_mv Buceta, David; Busto, Natalia; Barone, Giampaolo; Leal, José M.; Domínguez, Fernando; et al.; Ag2 and Ag3 Clusters: Synthesis, Characterization, and Interaction with DNA; Wiley; Angewandte Chemie; 54; 26; 5-2015; 7612-7616
1433-7851
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/
info:eu-repo/semantics/altIdentifier/doi/10.1002/anie.201502917
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/anie.201502917/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.000565

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