Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers

Autores
Lissarrague, Maria Haydee; Fascio, Mirta Liliana; Goyanes, Silvia Nair; D'accorso, Norma Beatriz
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A new biomedical material to be used as part of acrylic bone cement formulations is described. This new material is tough, its Young's Modulus is similar to the one of poly (methylmethacrylate) and the contrast agent, usually employed in acrylic bone cements, is homogeneously distributed among the polymeric matrix. Additionally, its wear coefficient is 66% lower than the one measured in poly(methyl methacrylate). The developed material is a branched polymer with polyisoprene backbone and poly(methyl methacrylate) side chains, which are capable of retaining barium sulphate nanoparticles thus avoiding their aggregation. The grafting reaction was carried out in presence of the nanoparticles, using methyl methacrylate as solvent. From the 1H-NMR spectra it was possible to determine the average number of MMA units per unit of isoprene (3.75:1). The ability to retain nanoparticles (about 8 wt.%), attributed to their interaction with the polymer branches, was determined by thermogravimetric analysis and confirmed by FTIR and microscopy techniques. By SEM microscopy it was also possible to determine the homogeneous spatial distribution of the barium sulphate nanoparticles along the polymer matrix.
Fil: Lissarrague, Maria Haydee. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física. Laboratorio de Polímeros y Materiales Compuestos; Argentina
Fil: Fascio, Mirta Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Goyanes, Silvia Nair. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física. Laboratorio de Polímeros y Materiales Compuestos; Argentina
Fil: D'accorso, Norma Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
Materia
Branched Polymer
Poly(Methyl Methacrylate)
Natural Rubber
Polyisoprene
Barium Sulphate Nanoparticles
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/42706
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/42706
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Improving bone cement toughness and contrast agent confinement by using acrylic branched polymersLissarrague, Maria HaydeeFascio, Mirta LilianaGoyanes, Silvia NairD'accorso, Norma BeatrizBranched PolymerPoly(Methyl Methacrylate)Natural RubberPolyisopreneBarium Sulphate Nanoparticleshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A new biomedical material to be used as part of acrylic bone cement formulations is described. This new material is tough, its Young's Modulus is similar to the one of poly (methylmethacrylate) and the contrast agent, usually employed in acrylic bone cements, is homogeneously distributed among the polymeric matrix. Additionally, its wear coefficient is 66% lower than the one measured in poly(methyl methacrylate). The developed material is a branched polymer with polyisoprene backbone and poly(methyl methacrylate) side chains, which are capable of retaining barium sulphate nanoparticles thus avoiding their aggregation. The grafting reaction was carried out in presence of the nanoparticles, using methyl methacrylate as solvent. From the 1H-NMR spectra it was possible to determine the average number of MMA units per unit of isoprene (3.75:1). The ability to retain nanoparticles (about 8 wt.%), attributed to their interaction with the polymer branches, was determined by thermogravimetric analysis and confirmed by FTIR and microscopy techniques. By SEM microscopy it was also possible to determine the homogeneous spatial distribution of the barium sulphate nanoparticles along the polymer matrix.Fil: Lissarrague, Maria Haydee. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física. Laboratorio de Polímeros y Materiales Compuestos; ArgentinaFil: Fascio, Mirta Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaFil: Goyanes, Silvia Nair. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física. Laboratorio de Polímeros y Materiales Compuestos; ArgentinaFil: D'accorso, Norma Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; ArgentinaElsevier Science2016-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/42706Lissarrague, Maria Haydee; Fascio, Mirta Liliana; Goyanes, Silvia Nair; D'accorso, Norma Beatriz; Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers; Elsevier Science; Materials Science and Engineering: C; 59; 2-2016; 901-9080928-4931CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0928493115305312info:eu-repo/semantics/altIdentifier/doi/10.1016/j.msec.2015.10.097info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:34:39Zoai:ri.conicet.gov.ar:11336/42706instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:34:39.337CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
title Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
spellingShingle Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
Lissarrague, Maria Haydee
Branched Polymer
Poly(Methyl Methacrylate)
Natural Rubber
Polyisoprene
Barium Sulphate Nanoparticles
title_short Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
title_full Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
title_fullStr Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
title_full_unstemmed Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
title_sort Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers
dc.creator.none.fl_str_mv Lissarrague, Maria Haydee
Fascio, Mirta Liliana
Goyanes, Silvia Nair
D'accorso, Norma Beatriz
author Lissarrague, Maria Haydee
author_facet Lissarrague, Maria Haydee
Fascio, Mirta Liliana
Goyanes, Silvia Nair
D'accorso, Norma Beatriz
author_role author
author2 Fascio, Mirta Liliana
Goyanes, Silvia Nair
D'accorso, Norma Beatriz
author2_role author
author
author
dc.subject.none.fl_str_mv Branched Polymer
Poly(Methyl Methacrylate)
Natural Rubber
Polyisoprene
Barium Sulphate Nanoparticles
topic Branched Polymer
Poly(Methyl Methacrylate)
Natural Rubber
Polyisoprene
Barium Sulphate Nanoparticles
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A new biomedical material to be used as part of acrylic bone cement formulations is described. This new material is tough, its Young's Modulus is similar to the one of poly (methylmethacrylate) and the contrast agent, usually employed in acrylic bone cements, is homogeneously distributed among the polymeric matrix. Additionally, its wear coefficient is 66% lower than the one measured in poly(methyl methacrylate). The developed material is a branched polymer with polyisoprene backbone and poly(methyl methacrylate) side chains, which are capable of retaining barium sulphate nanoparticles thus avoiding their aggregation. The grafting reaction was carried out in presence of the nanoparticles, using methyl methacrylate as solvent. From the 1H-NMR spectra it was possible to determine the average number of MMA units per unit of isoprene (3.75:1). The ability to retain nanoparticles (about 8 wt.%), attributed to their interaction with the polymer branches, was determined by thermogravimetric analysis and confirmed by FTIR and microscopy techniques. By SEM microscopy it was also possible to determine the homogeneous spatial distribution of the barium sulphate nanoparticles along the polymer matrix.
Fil: Lissarrague, Maria Haydee. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física. Laboratorio de Polímeros y Materiales Compuestos; Argentina
Fil: Fascio, Mirta Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
Fil: Goyanes, Silvia Nair. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física. Laboratorio de Polímeros y Materiales Compuestos; Argentina
Fil: D'accorso, Norma Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones en Hidratos de Carbono. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones en Hidratos de Carbono; Argentina
description A new biomedical material to be used as part of acrylic bone cement formulations is described. This new material is tough, its Young's Modulus is similar to the one of poly (methylmethacrylate) and the contrast agent, usually employed in acrylic bone cements, is homogeneously distributed among the polymeric matrix. Additionally, its wear coefficient is 66% lower than the one measured in poly(methyl methacrylate). The developed material is a branched polymer with polyisoprene backbone and poly(methyl methacrylate) side chains, which are capable of retaining barium sulphate nanoparticles thus avoiding their aggregation. The grafting reaction was carried out in presence of the nanoparticles, using methyl methacrylate as solvent. From the 1H-NMR spectra it was possible to determine the average number of MMA units per unit of isoprene (3.75:1). The ability to retain nanoparticles (about 8 wt.%), attributed to their interaction with the polymer branches, was determined by thermogravimetric analysis and confirmed by FTIR and microscopy techniques. By SEM microscopy it was also possible to determine the homogeneous spatial distribution of the barium sulphate nanoparticles along the polymer matrix.
publishDate 2016
dc.date.none.fl_str_mv 2016-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/42706
Lissarrague, Maria Haydee; Fascio, Mirta Liliana; Goyanes, Silvia Nair; D'accorso, Norma Beatriz; Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers; Elsevier Science; Materials Science and Engineering: C; 59; 2-2016; 901-908
0928-4931
CONICET Digital
CONICET
url http://hdl.handle.net/11336/42706
identifier_str_mv Lissarrague, Maria Haydee; Fascio, Mirta Liliana; Goyanes, Silvia Nair; D'accorso, Norma Beatriz; Improving bone cement toughness and contrast agent confinement by using acrylic branched polymers; Elsevier Science; Materials Science and Engineering: C; 59; 2-2016; 901-908
0928-4931
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0928493115305312
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.msec.2015.10.097
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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