Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2

Autores
Tarifa, Enrique Eduardo; Dosso, Liza Ainalen; Vera, Carlos Roman
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Air sanitization acquired renewed interest during the COVID 19 outbreak, especially for hospital rooms and intensive care units. In this work, a mathematical analysis was done of the convenience of sanitizing the air of whole rooms or personalized isolation tents. Centralized air sanitization was found to have low effectiveness due to three reasons: (i) the constant virus emission from patients; (ii) the practical up-per limits of air recycle flowrates; (iii) the low value of the minimum infective dose of SARS CoV 2. Personalized air sanitization was the best option. Virus inactivation by thermal effect was then revisited, and a steady-state model was formulated for an efficient and personalized thermal sterilizer. An analytical solution was obtained for temperature and virus concentration in different parts of the sterilizer. Cell tempera-ture was found to be the main variable for sterilization due to the Arrhenius-like form of the kinetic constant of virus deactivation. A cost objective function was written and subjected to conditions of minimum patient ventilation rate and mini-mum virus removal effectiveness. Numerical optimization gave an optimal design with the intrinsic advantages of thermal sanitization; i.e., simplicity, robustness, minimum maintenance and high sanitization rate.
Fil: Tarifa, Enrique Eduardo. Universidad Nacional de Jujuy. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Dosso, Liza Ainalen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; Argentina
Fil: Vera, Carlos Roman. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; Argentina
Materia
COVID-19
ECONOMIZER
MODELLING
THERMAL STERILIZATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/210646
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2Tarifa, Enrique EduardoDosso, Liza AinalenVera, Carlos RomanCOVID-19ECONOMIZERMODELLINGTHERMAL STERILIZATIONhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2Air sanitization acquired renewed interest during the COVID 19 outbreak, especially for hospital rooms and intensive care units. In this work, a mathematical analysis was done of the convenience of sanitizing the air of whole rooms or personalized isolation tents. Centralized air sanitization was found to have low effectiveness due to three reasons: (i) the constant virus emission from patients; (ii) the practical up-per limits of air recycle flowrates; (iii) the low value of the minimum infective dose of SARS CoV 2. Personalized air sanitization was the best option. Virus inactivation by thermal effect was then revisited, and a steady-state model was formulated for an efficient and personalized thermal sterilizer. An analytical solution was obtained for temperature and virus concentration in different parts of the sterilizer. Cell tempera-ture was found to be the main variable for sterilization due to the Arrhenius-like form of the kinetic constant of virus deactivation. A cost objective function was written and subjected to conditions of minimum patient ventilation rate and mini-mum virus removal effectiveness. Numerical optimization gave an optimal design with the intrinsic advantages of thermal sanitization; i.e., simplicity, robustness, minimum maintenance and high sanitization rate.Fil: Tarifa, Enrique Eduardo. Universidad Nacional de Jujuy. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Dosso, Liza Ainalen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; ArgentinaFil: Vera, Carlos Roman. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; ArgentinaScientific Research Publishing2022-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/210646Tarifa, Enrique Eduardo; Dosso, Liza Ainalen; Vera, Carlos Roman; Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2; Scientific Research Publishing; Open Journal of Applied Sciences; 12; 7; 7-2022; 1152-11732165-3917CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.scirp.org/journal/paperinformation.aspx?paperid=118477info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-12T09:53:43Zoai:ri.conicet.gov.ar:11336/210646instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-12 09:53:43.802CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
title Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
spellingShingle Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
Tarifa, Enrique Eduardo
COVID-19
ECONOMIZER
MODELLING
THERMAL STERILIZATION
title_short Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
title_full Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
title_fullStr Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
title_full_unstemmed Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
title_sort Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2
dc.creator.none.fl_str_mv Tarifa, Enrique Eduardo
Dosso, Liza Ainalen
Vera, Carlos Roman
author Tarifa, Enrique Eduardo
author_facet Tarifa, Enrique Eduardo
Dosso, Liza Ainalen
Vera, Carlos Roman
author_role author
author2 Dosso, Liza Ainalen
Vera, Carlos Roman
author2_role author
author
dc.subject.none.fl_str_mv COVID-19
ECONOMIZER
MODELLING
THERMAL STERILIZATION
topic COVID-19
ECONOMIZER
MODELLING
THERMAL STERILIZATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Air sanitization acquired renewed interest during the COVID 19 outbreak, especially for hospital rooms and intensive care units. In this work, a mathematical analysis was done of the convenience of sanitizing the air of whole rooms or personalized isolation tents. Centralized air sanitization was found to have low effectiveness due to three reasons: (i) the constant virus emission from patients; (ii) the practical up-per limits of air recycle flowrates; (iii) the low value of the minimum infective dose of SARS CoV 2. Personalized air sanitization was the best option. Virus inactivation by thermal effect was then revisited, and a steady-state model was formulated for an efficient and personalized thermal sterilizer. An analytical solution was obtained for temperature and virus concentration in different parts of the sterilizer. Cell tempera-ture was found to be the main variable for sterilization due to the Arrhenius-like form of the kinetic constant of virus deactivation. A cost objective function was written and subjected to conditions of minimum patient ventilation rate and mini-mum virus removal effectiveness. Numerical optimization gave an optimal design with the intrinsic advantages of thermal sanitization; i.e., simplicity, robustness, minimum maintenance and high sanitization rate.
Fil: Tarifa, Enrique Eduardo. Universidad Nacional de Jujuy. Facultad de Ingeniería; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Dosso, Liza Ainalen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; Argentina
Fil: Vera, Carlos Roman. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera". Universidad Nacional del Litoral. Instituto de Investigaciones en Catálisis y Petroquímica "Ing. José Miguel Parera"; Argentina
description Air sanitization acquired renewed interest during the COVID 19 outbreak, especially for hospital rooms and intensive care units. In this work, a mathematical analysis was done of the convenience of sanitizing the air of whole rooms or personalized isolation tents. Centralized air sanitization was found to have low effectiveness due to three reasons: (i) the constant virus emission from patients; (ii) the practical up-per limits of air recycle flowrates; (iii) the low value of the minimum infective dose of SARS CoV 2. Personalized air sanitization was the best option. Virus inactivation by thermal effect was then revisited, and a steady-state model was formulated for an efficient and personalized thermal sterilizer. An analytical solution was obtained for temperature and virus concentration in different parts of the sterilizer. Cell tempera-ture was found to be the main variable for sterilization due to the Arrhenius-like form of the kinetic constant of virus deactivation. A cost objective function was written and subjected to conditions of minimum patient ventilation rate and mini-mum virus removal effectiveness. Numerical optimization gave an optimal design with the intrinsic advantages of thermal sanitization; i.e., simplicity, robustness, minimum maintenance and high sanitization rate.
publishDate 2022
dc.date.none.fl_str_mv 2022-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/210646
Tarifa, Enrique Eduardo; Dosso, Liza Ainalen; Vera, Carlos Roman; Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2; Scientific Research Publishing; Open Journal of Applied Sciences; 12; 7; 7-2022; 1152-1173
2165-3917
CONICET Digital
CONICET
url http://hdl.handle.net/11336/210646
identifier_str_mv Tarifa, Enrique Eduardo; Dosso, Liza Ainalen; Vera, Carlos Roman; Analysis of Virus Sanitization Alternatives and Optimization of a Thermal Air Purifier for SARS-CoV-2; Scientific Research Publishing; Open Journal of Applied Sciences; 12; 7; 7-2022; 1152-1173
2165-3917
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.scirp.org/journal/paperinformation.aspx?paperid=118477
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Scientific Research Publishing
publisher.none.fl_str_mv Scientific Research Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1848598230601826304
score 13.24909

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