Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens

Autores
García Mitacek, María Carla; Stornelli, María Cecilia; Praderio, Romina Gisele; Stornelli, María Alejandra; de la Sota, Rodolfo Luzbel
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Contents: The objective of this study was to evaluate the efficacy of cloprostenol (CLO) or aglepristone (ALI) for pregnancy termination in queens at 21-22 and 35-38 days of gestation. Two experiments (EXP) were carried out to accomplish this aim. Thirty-seven 12- to 14-month-old mixed breed queens were used in a randomized design. At oestrus, queens were housed for mating with a tom, and pregnancy was confirmed by transabdominal ultrasonographic examination (US). On days 21-22 of pregnancy (EXP1) or 35-38 of pregnancy (EXP2), queens were divided into three groups (G). Queens in G1 received ALI (10 mg/kg, sc; EXP1, n = 6; EXP2, n = 6) on two consecutive days. Queens in G2 received CLO (5 μg/kg, sc; EXP1, n = 6; EXP2 = 7) on three consecutive days. Queens in G3 received 1 ml of saline solution (PLA, sc; EXP1, n = 6; EXP2 = 6). After treatment, females were monitored daily by US during for 10 days and weekly until the end of gestation. In EXP1, pregnancy was terminated in (6/6, 100%), (0/6, 0%) and (0/6, 0%), for the ALI, CLO and PLA groups, respectively (p < 0.001). In EXP2, pregnancy was terminated in (6/6, 100%), (1/7, 14%) and (0/6, 0%) for the ALI, CLO and PLA groups, respectively (p < 0.001). In both EXP, after CLO administration, animals vomited and were depressed for 30 min; but no side effects were observed in the animals in the ALI group. In conclusion, the results from this study indicate that three injections of CLO are not effective, but two injections of ALI are effective to induce abortion in queens at 21-22 or 35-38 days of pregnancy. © 2012 Blackwell Verlag GmbH.
Fil: García Mitacek, María Carla. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: Stornelli, María Cecilia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: Praderio, Romina Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: Stornelli, María Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: de la Sota, Rodolfo Luzbel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Materia
Queen
Pregnancy Termination
Cloprostenol
Aglepristone
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/75473
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/75473
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in QueensGarcía Mitacek, María CarlaStornelli, María CeciliaPraderio, Romina GiseleStornelli, María Alejandrade la Sota, Rodolfo LuzbelQueenPregnancy TerminationCloprostenolAglepristonehttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Contents: The objective of this study was to evaluate the efficacy of cloprostenol (CLO) or aglepristone (ALI) for pregnancy termination in queens at 21-22 and 35-38 days of gestation. Two experiments (EXP) were carried out to accomplish this aim. Thirty-seven 12- to 14-month-old mixed breed queens were used in a randomized design. At oestrus, queens were housed for mating with a tom, and pregnancy was confirmed by transabdominal ultrasonographic examination (US). On days 21-22 of pregnancy (EXP1) or 35-38 of pregnancy (EXP2), queens were divided into three groups (G). Queens in G1 received ALI (10 mg/kg, sc; EXP1, n = 6; EXP2, n = 6) on two consecutive days. Queens in G2 received CLO (5 μg/kg, sc; EXP1, n = 6; EXP2 = 7) on three consecutive days. Queens in G3 received 1 ml of saline solution (PLA, sc; EXP1, n = 6; EXP2 = 6). After treatment, females were monitored daily by US during for 10 days and weekly until the end of gestation. In EXP1, pregnancy was terminated in (6/6, 100%), (0/6, 0%) and (0/6, 0%), for the ALI, CLO and PLA groups, respectively (p < 0.001). In EXP2, pregnancy was terminated in (6/6, 100%), (1/7, 14%) and (0/6, 0%) for the ALI, CLO and PLA groups, respectively (p < 0.001). In both EXP, after CLO administration, animals vomited and were depressed for 30 min; but no side effects were observed in the animals in the ALI group. In conclusion, the results from this study indicate that three injections of CLO are not effective, but two injections of ALI are effective to induce abortion in queens at 21-22 or 35-38 days of pregnancy. © 2012 Blackwell Verlag GmbH.Fil: García Mitacek, María Carla. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; ArgentinaFil: Stornelli, María Cecilia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; ArgentinaFil: Praderio, Romina Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; ArgentinaFil: Stornelli, María Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; ArgentinaFil: de la Sota, Rodolfo Luzbel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; ArgentinaWiley Blackwell Publishing, Inc2012-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/75473García Mitacek, María Carla; Stornelli, María Cecilia; Praderio, Romina Gisele; Stornelli, María Alejandra; de la Sota, Rodolfo Luzbel; Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens; Wiley Blackwell Publishing, Inc; Reproduction in Domestic Animals; 47; SUPPL. 6; 12-2012; 200-2030936-67681439-0531CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/rda.12023info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/rda.12023info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:32:02Zoai:ri.conicet.gov.ar:11336/75473instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:32:02.641CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
title Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
spellingShingle Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
García Mitacek, María Carla
Queen
Pregnancy Termination
Cloprostenol
Aglepristone
title_short Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
title_full Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
title_fullStr Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
title_full_unstemmed Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
title_sort Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens
dc.creator.none.fl_str_mv García Mitacek, María Carla
Stornelli, María Cecilia
Praderio, Romina Gisele
Stornelli, María Alejandra
de la Sota, Rodolfo Luzbel
author García Mitacek, María Carla
author_facet García Mitacek, María Carla
Stornelli, María Cecilia
Praderio, Romina Gisele
Stornelli, María Alejandra
de la Sota, Rodolfo Luzbel
author_role author
author2 Stornelli, María Cecilia
Praderio, Romina Gisele
Stornelli, María Alejandra
de la Sota, Rodolfo Luzbel
author2_role author
author
author
author
dc.subject.none.fl_str_mv Queen
Pregnancy Termination
Cloprostenol
Aglepristone
topic Queen
Pregnancy Termination
Cloprostenol
Aglepristone
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Contents: The objective of this study was to evaluate the efficacy of cloprostenol (CLO) or aglepristone (ALI) for pregnancy termination in queens at 21-22 and 35-38 days of gestation. Two experiments (EXP) were carried out to accomplish this aim. Thirty-seven 12- to 14-month-old mixed breed queens were used in a randomized design. At oestrus, queens were housed for mating with a tom, and pregnancy was confirmed by transabdominal ultrasonographic examination (US). On days 21-22 of pregnancy (EXP1) or 35-38 of pregnancy (EXP2), queens were divided into three groups (G). Queens in G1 received ALI (10 mg/kg, sc; EXP1, n = 6; EXP2, n = 6) on two consecutive days. Queens in G2 received CLO (5 μg/kg, sc; EXP1, n = 6; EXP2 = 7) on three consecutive days. Queens in G3 received 1 ml of saline solution (PLA, sc; EXP1, n = 6; EXP2 = 6). After treatment, females were monitored daily by US during for 10 days and weekly until the end of gestation. In EXP1, pregnancy was terminated in (6/6, 100%), (0/6, 0%) and (0/6, 0%), for the ALI, CLO and PLA groups, respectively (p < 0.001). In EXP2, pregnancy was terminated in (6/6, 100%), (1/7, 14%) and (0/6, 0%) for the ALI, CLO and PLA groups, respectively (p < 0.001). In both EXP, after CLO administration, animals vomited and were depressed for 30 min; but no side effects were observed in the animals in the ALI group. In conclusion, the results from this study indicate that three injections of CLO are not effective, but two injections of ALI are effective to induce abortion in queens at 21-22 or 35-38 days of pregnancy. © 2012 Blackwell Verlag GmbH.
Fil: García Mitacek, María Carla. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: Stornelli, María Cecilia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: Praderio, Romina Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: Stornelli, María Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
Fil: de la Sota, Rodolfo Luzbel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Teriogenología. Cátedra de Reproducción Animal; Argentina
description Contents: The objective of this study was to evaluate the efficacy of cloprostenol (CLO) or aglepristone (ALI) for pregnancy termination in queens at 21-22 and 35-38 days of gestation. Two experiments (EXP) were carried out to accomplish this aim. Thirty-seven 12- to 14-month-old mixed breed queens were used in a randomized design. At oestrus, queens were housed for mating with a tom, and pregnancy was confirmed by transabdominal ultrasonographic examination (US). On days 21-22 of pregnancy (EXP1) or 35-38 of pregnancy (EXP2), queens were divided into three groups (G). Queens in G1 received ALI (10 mg/kg, sc; EXP1, n = 6; EXP2, n = 6) on two consecutive days. Queens in G2 received CLO (5 μg/kg, sc; EXP1, n = 6; EXP2 = 7) on three consecutive days. Queens in G3 received 1 ml of saline solution (PLA, sc; EXP1, n = 6; EXP2 = 6). After treatment, females were monitored daily by US during for 10 days and weekly until the end of gestation. In EXP1, pregnancy was terminated in (6/6, 100%), (0/6, 0%) and (0/6, 0%), for the ALI, CLO and PLA groups, respectively (p < 0.001). In EXP2, pregnancy was terminated in (6/6, 100%), (1/7, 14%) and (0/6, 0%) for the ALI, CLO and PLA groups, respectively (p < 0.001). In both EXP, after CLO administration, animals vomited and were depressed for 30 min; but no side effects were observed in the animals in the ALI group. In conclusion, the results from this study indicate that three injections of CLO are not effective, but two injections of ALI are effective to induce abortion in queens at 21-22 or 35-38 days of pregnancy. © 2012 Blackwell Verlag GmbH.
publishDate 2012
dc.date.none.fl_str_mv 2012-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/75473
García Mitacek, María Carla; Stornelli, María Cecilia; Praderio, Romina Gisele; Stornelli, María Alejandra; de la Sota, Rodolfo Luzbel; Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens; Wiley Blackwell Publishing, Inc; Reproduction in Domestic Animals; 47; SUPPL. 6; 12-2012; 200-203
0936-6768
1439-0531
CONICET Digital
CONICET
url http://hdl.handle.net/11336/75473
identifier_str_mv García Mitacek, María Carla; Stornelli, María Cecilia; Praderio, Romina Gisele; Stornelli, María Alejandra; de la Sota, Rodolfo Luzbel; Efficacy of Cloprostenol or Aglepristone at 21-22 and 35-38 Days of Gestation for Pregnancy Termination in Queens; Wiley Blackwell Publishing, Inc; Reproduction in Domestic Animals; 47; SUPPL. 6; 12-2012; 200-203
0936-6768
1439-0531
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/rda.12023
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/rda.12023
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.221938

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