Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development

Autores
Dain, Sergio Alejandro; Repossi Marquez, Pablo Gaston; Das, Undurti N.; Eynard, Aldo Renato
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The essential polyunsaturated fatty acids (PUFAs) serve as precursors of the endocannabinoids (EC), bioactive lipids molecules. This article reviews the functions of the endocannabinoid system (ECS), and their relationship some physiological and pathological processes, with focus in development of obesity and diabetes. Furthermore, a brief overview on the experimental and clinical effects of drugs modification of the ECS and results of the exogenous manipulation of PUFAs and consequent modulation on ECS are also outlined.

Finally, we propose that the ECS can be modulated by exogenous manipulation of PUFAs that could help in the prevention and management of very important human diseases like obesity, metabolic sindrome and diabetes.
Fil: Dain, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Repossi Marquez, Pablo Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Das, Undurti N.. Jawaharlal Nehru Technological University; India
Fil: Eynard, Aldo Renato. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina

Materia
ENDOCANNABINOIDS
POLYUNSATURATED FATTY ACIDS
HUMAN OBESITY
DIABETES DEVELOPMENT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/130091
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes developmentDain, Sergio AlejandroRepossi Marquez, Pablo GastonDas, Undurti N.Eynard, Aldo RenatoENDOCANNABINOIDSPOLYUNSATURATED FATTY ACIDSHUMAN OBESITYDIABETES DEVELOPMENThttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3The essential polyunsaturated fatty acids (PUFAs) serve as precursors of the endocannabinoids (EC), bioactive lipids molecules. This article reviews the functions of the endocannabinoid system (ECS), and their relationship some physiological and pathological processes, with focus in development of obesity and diabetes. Furthermore, a brief overview on the experimental and clinical effects of drugs modification of the ECS and results of the exogenous manipulation of PUFAs and consequent modulation on ECS are also outlined. <o:p /></span></p> <p class="MsoNormal" style="text-align: justify; line-height: 150%;"><span lang="en" style="font-family: Arial;">Finally, we propose that the ECS can be modulated by exogenous manipulation of PUFAs that could help in the prevention and management of very important human diseases like obesity, metabolic sindrome and diabetes.Fil: Dain, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; ArgentinaFil: Repossi Marquez, Pablo Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Das, Undurti N.. Jawaharlal Nehru Technological University; IndiaFil: Eynard, Aldo Renato. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaBioscience Research Institute2010-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/130091Dain, Sergio Alejandro; Repossi Marquez, Pablo Gaston; Das, Undurti N.; Eynard, Aldo Renato; Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development; Bioscience Research Institute; Frontiers in Bioscience; E2; 3-2010; 1432-14471093-99461093-4715CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/20515815/info:eu-repo/semantics/altIdentifier/doi/10.2741/e203info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:05:22Zoai:ri.conicet.gov.ar:11336/130091instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:05:22.928CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
title Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
spellingShingle Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
Dain, Sergio Alejandro
ENDOCANNABINOIDS
POLYUNSATURATED FATTY ACIDS
HUMAN OBESITY
DIABETES DEVELOPMENT
title_short Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
title_full Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
title_fullStr Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
title_full_unstemmed Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
title_sort Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development
dc.creator.none.fl_str_mv Dain, Sergio Alejandro
Repossi Marquez, Pablo Gaston
Das, Undurti N.
Eynard, Aldo Renato
author Dain, Sergio Alejandro
author_facet Dain, Sergio Alejandro
Repossi Marquez, Pablo Gaston
Das, Undurti N.
Eynard, Aldo Renato
author_role author
author2 Repossi Marquez, Pablo Gaston
Das, Undurti N.
Eynard, Aldo Renato
author2_role author
author
author
dc.subject.none.fl_str_mv ENDOCANNABINOIDS
POLYUNSATURATED FATTY ACIDS
HUMAN OBESITY
DIABETES DEVELOPMENT
topic ENDOCANNABINOIDS
POLYUNSATURATED FATTY ACIDS
HUMAN OBESITY
DIABETES DEVELOPMENT
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The essential polyunsaturated fatty acids (PUFAs) serve as precursors of the endocannabinoids (EC), bioactive lipids molecules. This article reviews the functions of the endocannabinoid system (ECS), and their relationship some physiological and pathological processes, with focus in development of obesity and diabetes. Furthermore, a brief overview on the experimental and clinical effects of drugs modification of the ECS and results of the exogenous manipulation of PUFAs and consequent modulation on ECS are also outlined. <o:p /></span></p> <p class="MsoNormal" style="text-align: justify; line-height: 150%;"><span lang="en" style="font-family: Arial;">Finally, we propose that the ECS can be modulated by exogenous manipulation of PUFAs that could help in the prevention and management of very important human diseases like obesity, metabolic sindrome and diabetes.
Fil: Dain, Sergio Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina
Fil: Repossi Marquez, Pablo Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
Fil: Das, Undurti N.. Jawaharlal Nehru Technological University; India
Fil: Eynard, Aldo Renato. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
description The essential polyunsaturated fatty acids (PUFAs) serve as precursors of the endocannabinoids (EC), bioactive lipids molecules. This article reviews the functions of the endocannabinoid system (ECS), and their relationship some physiological and pathological processes, with focus in development of obesity and diabetes. Furthermore, a brief overview on the experimental and clinical effects of drugs modification of the ECS and results of the exogenous manipulation of PUFAs and consequent modulation on ECS are also outlined. <o:p /></span></p> <p class="MsoNormal" style="text-align: justify; line-height: 150%;"><span lang="en" style="font-family: Arial;">Finally, we propose that the ECS can be modulated by exogenous manipulation of PUFAs that could help in the prevention and management of very important human diseases like obesity, metabolic sindrome and diabetes.
publishDate 2010
dc.date.none.fl_str_mv 2010-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/130091
Dain, Sergio Alejandro; Repossi Marquez, Pablo Gaston; Das, Undurti N.; Eynard, Aldo Renato; Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development; Bioscience Research Institute; Frontiers in Bioscience; E2; 3-2010; 1432-1447
1093-9946
1093-4715
CONICET Digital
CONICET
url http://hdl.handle.net/11336/130091
identifier_str_mv Dain, Sergio Alejandro; Repossi Marquez, Pablo Gaston; Das, Undurti N.; Eynard, Aldo Renato; Role of polyunsaturated fatty acids, the precursors of endocannabinoids, in human obesity and diabetes development; Bioscience Research Institute; Frontiers in Bioscience; E2; 3-2010; 1432-1447
1093-9946
1093-4715
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/20515815/
info:eu-repo/semantics/altIdentifier/doi/10.2741/e203
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bioscience Research Institute
publisher.none.fl_str_mv Bioscience Research Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613889018298368
score 13.070432

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