A genome-informed higher rank classification of the biotechnologically important fungal subphylum Saccharomycotina

• Autores: Groenewald, M.; Hittinger, Chris; Bensch, K.; Opulente, D. A.; Shen, X. X.; Li, Y.; Liu, C.; LaBella, A. L.; Zhou, Xudong; Limtong, S.; Jindamorakot, S.; Gonçalves, P.; Robert, V.; Wolfe, K. H.; Rosa, C. A.; Boekhout, T.; Cadez, N.; Péter, G.; Sampaio, J. P.; Lachance, M. A.; Yurkov, A. M.; Daniel, H. M.; Takashima, M.; Boundy Mills, K.; Libkind Frati, Diego; Aoki, K.; Sugita, Takafumi; Rokas, A.
• Año de publicación: 2023
• Idioma: inglés
• Tipo de recurso: artículo
• Materia: HIGHER RANK CLASSIFICATION; NOVEL TAXA; ORTHOLOGOUS GROUPS (OGS); SACCHAROMYCOTINA; TAXONOMY; YEASTS
• Institución: Consejo Nacional de Investigaciones Científicas y Técnicas

The subphylum Saccharomycotina is a lineage in the fungal phylum Ascomycota that exhibits levels of genomic diversity similar to those of plants and animals. The Saccharomycotina consist of more than 1 200 known species currently divided into 16 families, one order, and one class. Species in this subphylum are ecologically and metabolically diverse and include important opportunistic human pathogens, as well as species important in biotechnological applications. Many traits of biotechnological interest are found in closely related species and often restricted to single phylogenetic clades. However, the biotechnological potential of most yeast species remains unexplored. Although the subphylum Saccharomycotina has much higher rates of genome sequence evolution than its sister subphylum, Pezizomycotina, it contains only one class compared to the 16 classes in Pezizomycotina. The third subphylum of Ascomycota, the Taphrinomycotina, consists of six classes and has approximately 10 times fewer species than the Saccharomycotina. These data indicate that the current classification of all these yeasts into a single class and a single order is an underappreciation of their diversity. Our previous genome-scale phylogenetic analyses showed that the Saccharomycotina contains 12 major and robustly supported phylogenetic clades; seven of these are current families (Lipomycetaceae, Trigonopsidaceae, Alloascoideaceae, Pichiaceae, Phaffomycetaceae, Saccharomycodaceae, and Saccharomycetaceae), one comprises two current families (Dipodascaceae and Trichomonascaceae), one represents the genus Sporopachydermia, and three represent lineages that differ in their translation of the CUG codon (CUG-Ala, CUG-Ser1, and CUG-Ser2). Using these analyses in combination with relative evolutionary divergence and genome content analyses, we propose an updated classification for the Saccharomycotina, including seven classes and 12 orders that can be diagnosed by genome content. This updated classification is consistent with the high levels of genomic diversity within this subphylum and is necessary to make the higher rank classification of the Saccharomycotina more comparable to that of other fungi, as well as to communicate efficiently on lineages that are not yet formally named.
Fil: Groenewald, M.. Westerdijk Fungal Biodiversity Institute; Países Bajos
Fil: Hittinger, Chris. University of Wisconsin; Estados Unidos
Fil: Bensch, K.. Westerdijk Fungal Biodiversity Institute; Países Bajos
Fil: Opulente, D. A.. Villanova University; Estados Unidos. University of Wisconsin; Estados Unidos
Fil: Shen, X. X.. Zhejiang University; China
Fil: Li, Y.. Shandong University; China
Fil: Liu, C.. Zhejiang University; China
Fil: LaBella, A. L.. University of North Carolina; Estados Unidos
Fil: Zhou, Xudong. South China Agricultural University; China
Fil: Limtong, S.. Kasetsart University; Tailandia
Fil: Jindamorakot, S.. National Center For Genetic Engineering And Biotechnology; Tailandia
Fil: Gonçalves, P.. Universidade Nova de Lisboa. Faculdade de Ciencias e Tecnologia; Portugal
Fil: Robert, V.. Westerdijk Fungal Biodiversity Institute; Países Bajos
Fil: Wolfe, K. H.. Universidad de Dublin; Irlanda
Fil: Rosa, C. A.. Universidade Federal de Minas Gerais; Brasil
Fil: Boekhout, T.. King Saud University ; Arabia Saudita
Fil: Cadez, N.. University of Ljubljana; Eslovenia
Fil: Péter, G.. Hungarian University of Agriculture And Life Sciences; Hungría
Fil: Sampaio, J. P.. Universidade Nova de Lisboa. Faculdade de Ciencias e Tecnologia; Portugal
Fil: Lachance, M. A.. Western University; Canadá
Fil: Yurkov, A. M.. Leibniz Institute German Collection of Microorganisms and Cell Cultures; Alemania
Fil: Daniel, H. M.. Université Catholique de Louvain; Bélgica
Fil: Takashima, M.. Tokyo University of Agriculture; Japón
Fil: Boundy Mills, K.. University of California at Davis; Estados Unidos
Fil: Libkind Frati, Diego. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto Andino Patagónico de Tecnologías Biológicas y Geoambientales. Universidad Nacional del Comahue. Instituto Andino Patagónico de Tecnologías Biológicas y Geoambientales; Argentina
Fil: Aoki, K.. Tokyo University of Agriculture; Japón
Fil: Sugita, Takafumi. Meiji Pharmaceutical University; Japón
Fil: Rokas, A.. Vanderbilt University; Estados Unidos