User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario

Autores
Luna, Daniel R.; Rizzato Lede, Daniel A.; Rubin, Luciana; Otero, Carlos M.; Ortiz, Juan M.; García, Mónica G.; Rapisarda, Romina P.; Risk, Marcelo; González Bernaldo De Quirós, Fernán
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Decision support systems can alert physicians to the existence of drug interactions. The Hospital Italiano de Buenos Aires, Argentina, has an in-house electronic health record with computerized physician order entry and clinical decision support. It includes a drug-drug interaction alert system, initially developed under traditional engineering techniques. As we detected a high alert override rate, we rebuilt the knowledge database and redesigned the alert interface with User-Centered Design techniques. A laboratory crossover study using clinical vignettes showed that new alerts were more usable than traditional ones. This paper aimed to validate these results through a controlled and randomized experimental study with two branches (old vs. new design) in a real setting. We analyzed, quantitatively, every fired alert between April 2015 and September 2016. Finally, we performed user surveys and qualitative interviews to inquire about their satisfaction and perceptions. In real scenarios, user-centered design alerts were more usable, being more effective and satisfactory, but less efficient than traditional alerts. "Safe omission", as a new concept, emerged from our stratified analyses and interviews.
Fil: Luna, Daniel R.. Instituto Tecnológico de Buenos Aires; Argentina. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Rizzato Lede, Daniel A.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Rubin, Luciana. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Otero, Carlos M.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Ortiz, Juan M.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: García, Mónica G.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Rapisarda, Romina P.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Risk, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: González Bernaldo De Quirós, Fernán. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Materia
DRUG INTERACTIONS
EXPERT SYSTEMS
SOFTWARE DESIGN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/76315
Acceder
id CONICETDig_c05eee8e3dc8942d39fd7f1908b37178
oai_identifier_str oai:ri.conicet.gov.ar:11336/76315
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenarioLuna, Daniel R.Rizzato Lede, Daniel A.Rubin, LucianaOtero, Carlos M.Ortiz, Juan M.García, Mónica G.Rapisarda, Romina P.Risk, MarceloGonzález Bernaldo De Quirós, FernánDRUG INTERACTIONSEXPERT SYSTEMSSOFTWARE DESIGNhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Decision support systems can alert physicians to the existence of drug interactions. The Hospital Italiano de Buenos Aires, Argentina, has an in-house electronic health record with computerized physician order entry and clinical decision support. It includes a drug-drug interaction alert system, initially developed under traditional engineering techniques. As we detected a high alert override rate, we rebuilt the knowledge database and redesigned the alert interface with User-Centered Design techniques. A laboratory crossover study using clinical vignettes showed that new alerts were more usable than traditional ones. This paper aimed to validate these results through a controlled and randomized experimental study with two branches (old vs. new design) in a real setting. We analyzed, quantitatively, every fired alert between April 2015 and September 2016. Finally, we performed user surveys and qualitative interviews to inquire about their satisfaction and perceptions. In real scenarios, user-centered design alerts were more usable, being more effective and satisfactory, but less efficient than traditional alerts. "Safe omission", as a new concept, emerged from our stratified analyses and interviews.Fil: Luna, Daniel R.. Instituto Tecnológico de Buenos Aires; Argentina. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Rizzato Lede, Daniel A.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Rubin, Luciana. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Otero, Carlos M.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Ortiz, Juan M.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: García, Mónica G.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Rapisarda, Romina P.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Risk, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: González Bernaldo De Quirós, Fernán. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaIOS Press2017-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/76315Luna, Daniel R.; Rizzato Lede, Daniel A.; Rubin, Luciana; Otero, Carlos M.; Ortiz, Juan M.; et al.; User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario; IOS Press; Studies in Health Technology and Informatics; 245; 8-2017; 1085-10891879-83650926-9630CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://ebooks.iospress.nl/publication/48322info:eu-repo/semantics/altIdentifier/doi/10.3233/978-1-61499-830-3-1085info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:02:05Zoai:ri.conicet.gov.ar:11336/76315instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:02:05.668CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
title User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
spellingShingle User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
Luna, Daniel R.
DRUG INTERACTIONS
EXPERT SYSTEMS
SOFTWARE DESIGN
title_short User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
title_full User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
title_fullStr User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
title_full_unstemmed User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
title_sort User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario
dc.creator.none.fl_str_mv Luna, Daniel R.
Rizzato Lede, Daniel A.
Rubin, Luciana
Otero, Carlos M.
Ortiz, Juan M.
García, Mónica G.
Rapisarda, Romina P.
Risk, Marcelo
González Bernaldo De Quirós, Fernán
author Luna, Daniel R.
author_facet Luna, Daniel R.
Rizzato Lede, Daniel A.
Rubin, Luciana
Otero, Carlos M.
Ortiz, Juan M.
García, Mónica G.
Rapisarda, Romina P.
Risk, Marcelo
González Bernaldo De Quirós, Fernán
author_role author
author2 Rizzato Lede, Daniel A.
Rubin, Luciana
Otero, Carlos M.
Ortiz, Juan M.
García, Mónica G.
Rapisarda, Romina P.
Risk, Marcelo
González Bernaldo De Quirós, Fernán
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv DRUG INTERACTIONS
EXPERT SYSTEMS
SOFTWARE DESIGN
topic DRUG INTERACTIONS
EXPERT SYSTEMS
SOFTWARE DESIGN
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Decision support systems can alert physicians to the existence of drug interactions. The Hospital Italiano de Buenos Aires, Argentina, has an in-house electronic health record with computerized physician order entry and clinical decision support. It includes a drug-drug interaction alert system, initially developed under traditional engineering techniques. As we detected a high alert override rate, we rebuilt the knowledge database and redesigned the alert interface with User-Centered Design techniques. A laboratory crossover study using clinical vignettes showed that new alerts were more usable than traditional ones. This paper aimed to validate these results through a controlled and randomized experimental study with two branches (old vs. new design) in a real setting. We analyzed, quantitatively, every fired alert between April 2015 and September 2016. Finally, we performed user surveys and qualitative interviews to inquire about their satisfaction and perceptions. In real scenarios, user-centered design alerts were more usable, being more effective and satisfactory, but less efficient than traditional alerts. "Safe omission", as a new concept, emerged from our stratified analyses and interviews.
Fil: Luna, Daniel R.. Instituto Tecnológico de Buenos Aires; Argentina. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Rizzato Lede, Daniel A.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Rubin, Luciana. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Otero, Carlos M.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Ortiz, Juan M.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: García, Mónica G.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Rapisarda, Romina P.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: Risk, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Tecnológico de Buenos Aires; Argentina. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
Fil: González Bernaldo De Quirós, Fernán. Hospital Italiano. Instituto Universitario. Escuela de Medicina; Argentina
description Decision support systems can alert physicians to the existence of drug interactions. The Hospital Italiano de Buenos Aires, Argentina, has an in-house electronic health record with computerized physician order entry and clinical decision support. It includes a drug-drug interaction alert system, initially developed under traditional engineering techniques. As we detected a high alert override rate, we rebuilt the knowledge database and redesigned the alert interface with User-Centered Design techniques. A laboratory crossover study using clinical vignettes showed that new alerts were more usable than traditional ones. This paper aimed to validate these results through a controlled and randomized experimental study with two branches (old vs. new design) in a real setting. We analyzed, quantitatively, every fired alert between April 2015 and September 2016. Finally, we performed user surveys and qualitative interviews to inquire about their satisfaction and perceptions. In real scenarios, user-centered design alerts were more usable, being more effective and satisfactory, but less efficient than traditional alerts. "Safe omission", as a new concept, emerged from our stratified analyses and interviews.
publishDate 2017
dc.date.none.fl_str_mv 2017-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/76315
Luna, Daniel R.; Rizzato Lede, Daniel A.; Rubin, Luciana; Otero, Carlos M.; Ortiz, Juan M.; et al.; User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario; IOS Press; Studies in Health Technology and Informatics; 245; 8-2017; 1085-1089
1879-8365
0926-9630
CONICET Digital
CONICET
url http://hdl.handle.net/11336/76315
identifier_str_mv Luna, Daniel R.; Rizzato Lede, Daniel A.; Rubin, Luciana; Otero, Carlos M.; Ortiz, Juan M.; et al.; User-centered design improves the usability of drug-drug interaction alerts: A validation study in the real scenario; IOS Press; Studies in Health Technology and Informatics; 245; 8-2017; 1085-1089
1879-8365
0926-9630
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://ebooks.iospress.nl/publication/48322
info:eu-repo/semantics/altIdentifier/doi/10.3233/978-1-61499-830-3-1085
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv IOS Press
publisher.none.fl_str_mv IOS Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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