Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market

Autores
Han, Yong Ki; Simionato, Laura Daniela; Calvo, Romina G.; Mattei, María Belén; Segall, Adriana Ines
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In this work dissolution profiles of furosemide tablets of nine commercial products marketed in Argentine were evaluated. All brands fulfill the specifications of dissolution test of USP. Comparison of dissolution profiles were carried out by model-dependent and model independent approaches. Results obtained via model-dependent approach show a first order drug release mechanism especially for Brand I (reference) and Brand IV. Results obtained via modelindependent approach show that there was not significant difference in Dissolution efficiency between the reference product and Brands II, III and IV and in Mean dissolution time between the reference product and Brands II, III, IV and V. Using fit factors, only Brands I and III were similar.
Fil: Han, Yong Ki. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Simionato, Laura Daniela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Calvo, Romina G.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Mattei, María Belén. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Segall, Adriana Ines. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Materia
Furosemide
Tablets
Dissolution Profiles
Commercial Products
Model-Dependent
Model-Independent
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/30522
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean MarketHan, Yong KiSimionato, Laura DanielaCalvo, Romina G.Mattei, María BelénSegall, Adriana InesFurosemideTabletsDissolution ProfilesCommercial ProductsModel-DependentModel-Independenthttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3In this work dissolution profiles of furosemide tablets of nine commercial products marketed in Argentine were evaluated. All brands fulfill the specifications of dissolution test of USP. Comparison of dissolution profiles were carried out by model-dependent and model independent approaches. Results obtained via model-dependent approach show a first order drug release mechanism especially for Brand I (reference) and Brand IV. Results obtained via modelindependent approach show that there was not significant difference in Dissolution efficiency between the reference product and Brands II, III and IV and in Mean dissolution time between the reference product and Brands II, III, IV and V. Using fit factors, only Brands I and III were similar.Fil: Han, Yong Ki. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Simionato, Laura Daniela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Calvo, Romina G.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Mattei, María Belén. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Segall, Adriana Ines. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaLifescience Global2014-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/30522Han, Yong Ki; Simionato, Laura Daniela; Calvo, Romina G.; Mattei, María Belén; Segall, Adriana Ines; Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market; Lifescience Global; Journal of Applied Solution Chemistry and Modeling; 3; 4; 12-2014; 186-1931929-5030CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.6000/1929-5030.2014.03.04.1info:eu-repo/semantics/altIdentifier/url/http://www.lifescienceglobal.com/pms/index.php/JASCM/article/view/2603info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:10:55Zoai:ri.conicet.gov.ar:11336/30522instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:10:55.696CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
title Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
spellingShingle Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
Han, Yong Ki
Furosemide
Tablets
Dissolution Profiles
Commercial Products
Model-Dependent
Model-Independent
title_short Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
title_full Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
title_fullStr Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
title_full_unstemmed Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
title_sort Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market
dc.creator.none.fl_str_mv Han, Yong Ki
Simionato, Laura Daniela
Calvo, Romina G.
Mattei, María Belén
Segall, Adriana Ines
author Han, Yong Ki
author_facet Han, Yong Ki
Simionato, Laura Daniela
Calvo, Romina G.
Mattei, María Belén
Segall, Adriana Ines
author_role author
author2 Simionato, Laura Daniela
Calvo, Romina G.
Mattei, María Belén
Segall, Adriana Ines
author2_role author
author
author
author
dc.subject.none.fl_str_mv Furosemide
Tablets
Dissolution Profiles
Commercial Products
Model-Dependent
Model-Independent
topic Furosemide
Tablets
Dissolution Profiles
Commercial Products
Model-Dependent
Model-Independent
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv In this work dissolution profiles of furosemide tablets of nine commercial products marketed in Argentine were evaluated. All brands fulfill the specifications of dissolution test of USP. Comparison of dissolution profiles were carried out by model-dependent and model independent approaches. Results obtained via model-dependent approach show a first order drug release mechanism especially for Brand I (reference) and Brand IV. Results obtained via modelindependent approach show that there was not significant difference in Dissolution efficiency between the reference product and Brands II, III and IV and in Mean dissolution time between the reference product and Brands II, III, IV and V. Using fit factors, only Brands I and III were similar.
Fil: Han, Yong Ki. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
Fil: Simionato, Laura Daniela. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Calvo, Romina G.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Mattei, María Belén. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Segall, Adriana Ines. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina
description In this work dissolution profiles of furosemide tablets of nine commercial products marketed in Argentine were evaluated. All brands fulfill the specifications of dissolution test of USP. Comparison of dissolution profiles were carried out by model-dependent and model independent approaches. Results obtained via model-dependent approach show a first order drug release mechanism especially for Brand I (reference) and Brand IV. Results obtained via modelindependent approach show that there was not significant difference in Dissolution efficiency between the reference product and Brands II, III and IV and in Mean dissolution time between the reference product and Brands II, III, IV and V. Using fit factors, only Brands I and III were similar.
publishDate 2014
dc.date.none.fl_str_mv 2014-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/30522
Han, Yong Ki; Simionato, Laura Daniela; Calvo, Romina G.; Mattei, María Belén; Segall, Adriana Ines; Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market; Lifescience Global; Journal of Applied Solution Chemistry and Modeling; 3; 4; 12-2014; 186-193
1929-5030
CONICET Digital
CONICET
url http://hdl.handle.net/11336/30522
identifier_str_mv Han, Yong Ki; Simionato, Laura Daniela; Calvo, Romina G.; Mattei, María Belén; Segall, Adriana Ines; Comparison of Dissolution Profiles of Furosemide Tablets Available in the Argentinean Market; Lifescience Global; Journal of Applied Solution Chemistry and Modeling; 3; 4; 12-2014; 186-193
1929-5030
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.6000/1929-5030.2014.03.04.1
info:eu-repo/semantics/altIdentifier/url/http://www.lifescienceglobal.com/pms/index.php/JASCM/article/view/2603
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Lifescience Global
publisher.none.fl_str_mv Lifescience Global
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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