Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression
- Autores
- Turk, Gabriela Julia Ana; Carobene, Mauricio
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Extreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemic
Fil: Turk, Gabriela Julia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina
Fil: Carobene, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina - Materia
-
Hiv
Recombination
Fitness
Disease - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/47455
Ver los metadatos del registro completo
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Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease ProgressionTurk, Gabriela Julia AnaCarobene, MauricioHivRecombinationFitnessDiseasehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Extreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemicFil: Turk, Gabriela Julia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaFil: Carobene, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; ArgentinaElsevier2015-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/47455Turk, Gabriela Julia Ana; Carobene, Mauricio; Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression; Elsevier; EBioMedicine; 2; 3; 3-2015; 188-1892352-3964CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.ebiom.2015.02.011info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2352396415000596info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:36:33Zoai:ri.conicet.gov.ar:11336/47455instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:36:33.463CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
title |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
spellingShingle |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression Turk, Gabriela Julia Ana Hiv Recombination Fitness Disease |
title_short |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
title_full |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
title_fullStr |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
title_full_unstemmed |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
title_sort |
Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression |
dc.creator.none.fl_str_mv |
Turk, Gabriela Julia Ana Carobene, Mauricio |
author |
Turk, Gabriela Julia Ana |
author_facet |
Turk, Gabriela Julia Ana Carobene, Mauricio |
author_role |
author |
author2 |
Carobene, Mauricio |
author2_role |
author |
dc.subject.none.fl_str_mv |
Hiv Recombination Fitness Disease |
topic |
Hiv Recombination Fitness Disease |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
Extreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemic Fil: Turk, Gabriela Julia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina Fil: Carobene, Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina |
description |
Extreme genetic variability is the hallmark of HIV‐1 infection and itrepresents a major challenge for antiviral treatment and vaccine development.HIV‐1 group M dominates the global pandemic. This genetic diversity not only affects viral epidemiology but it is also linked to the mechanisms used by the virus to escape the patients´ natural humoral and cellular immune responses as well as antiretroviral drug´s action, thus precluding viral control. As a result, monitoring the genetic diversity of HIV‐1 and understanding its consequences onviral fitness is crucial to control the spread of the epidemic |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-03 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/47455 Turk, Gabriela Julia Ana; Carobene, Mauricio; Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression; Elsevier; EBioMedicine; 2; 3; 3-2015; 188-189 2352-3964 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/47455 |
identifier_str_mv |
Turk, Gabriela Julia Ana; Carobene, Mauricio; Deciphering How HIV‐1 Intersubtype Recombination Shapes Viral Fitness and Disease Progression; Elsevier; EBioMedicine; 2; 3; 3-2015; 188-189 2352-3964 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ebiom.2015.02.011 info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S2352396415000596 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613147400339456 |
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13.070432 |