Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro

Autores
Cabrera Fischer, Edmundo Ignacio; Santana, Daniel Bia; Zócalo, Yanina; Camus, Juan Manuel; Forteza, Eduardo de; Armentano, Ricardo Luis
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: The aims were to characterize in muscular arteries (a) the passive and active effects of the adventitia on vessel biomechanical properties and conduit function (CF), and (b) potential differences between the adventitial role in elastic and muscular arteries. Methods and Results: Ovine femoral arteries were studied in vivo and in vitro (reduced smooth muscle-tone) in a circulation mock-up during hemodynamic conditions similar to those found in vivo. Pressure and diameter were assessed before and after removing the adventitia. The arterial compliance, distensibility, stiffness β-index and CF were quantified. Results were compared with those obtained in brachiocephalic trunks. In vivo, after removing the adventitia there was a nonsignificant diameter reduction and an increase in stiffness (P<0.05). The CF decreased in the early recordings (P<0.02). In vitro, there were no biomechanical changes but vascular dilatation after the adventitia removal. Biomechanical changes associated with the adventitia removal were higher in muscular arteries, whereas diameter changes were major in elastic vessels. Conclusions: After removing the adventitia, (a) the arterial stiffness and CF were modified in vivo only, suggesting the changes could be ascribed to variations in smooth muscle tone, and (b) changes in elastic and muscular arteries were quantitatively different. (Circ J 2010; 74: 1014 - 1022).
Fil: Cabrera Fischer, Edmundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina
Fil: Santana, Daniel Bia. Universidad de la República; Uruguay
Fil: Zócalo, Yanina. Universidad de la República; Uruguay
Fil: Camus, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Universidad de Mendoza; Argentina
Fil: Forteza, Eduardo de. Universidad Favaloro; Argentina
Fil: Armentano, Ricardo Luis. Universidad Favaloro; Argentina. Universidad de la República; Uruguay
Materia
ADVENTITIA
ARTERIAL CONDUIT FUNCTION
ARTERIAL STIFFNESS
ELASTIC ARTERIES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/280208
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/280208
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In VitroCabrera Fischer, Edmundo IgnacioSantana, Daniel BiaZócalo, YaninaCamus, Juan ManuelForteza, Eduardo deArmentano, Ricardo LuisADVENTITIAARTERIAL CONDUIT FUNCTIONARTERIAL STIFFNESSELASTIC ARTERIEShttps://purl.org/becyt/ford/2.6https://purl.org/becyt/ford/2Background: The aims were to characterize in muscular arteries (a) the passive and active effects of the adventitia on vessel biomechanical properties and conduit function (CF), and (b) potential differences between the adventitial role in elastic and muscular arteries. Methods and Results: Ovine femoral arteries were studied in vivo and in vitro (reduced smooth muscle-tone) in a circulation mock-up during hemodynamic conditions similar to those found in vivo. Pressure and diameter were assessed before and after removing the adventitia. The arterial compliance, distensibility, stiffness β-index and CF were quantified. Results were compared with those obtained in brachiocephalic trunks. In vivo, after removing the adventitia there was a nonsignificant diameter reduction and an increase in stiffness (P<0.05). The CF decreased in the early recordings (P<0.02). In vitro, there were no biomechanical changes but vascular dilatation after the adventitia removal. Biomechanical changes associated with the adventitia removal were higher in muscular arteries, whereas diameter changes were major in elastic vessels. Conclusions: After removing the adventitia, (a) the arterial stiffness and CF were modified in vivo only, suggesting the changes could be ascribed to variations in smooth muscle tone, and (b) changes in elastic and muscular arteries were quantitatively different. (Circ J 2010; 74: 1014 - 1022).Fil: Cabrera Fischer, Edmundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; ArgentinaFil: Santana, Daniel Bia. Universidad de la República; UruguayFil: Zócalo, Yanina. Universidad de la República; UruguayFil: Camus, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Universidad de Mendoza; ArgentinaFil: Forteza, Eduardo de. Universidad Favaloro; ArgentinaFil: Armentano, Ricardo Luis. Universidad Favaloro; Argentina. Universidad de la República; UruguayJapanese Circulation Soc2010-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/280208Cabrera Fischer, Edmundo Ignacio; Santana, Daniel Bia; Zócalo, Yanina; Camus, Juan Manuel; Forteza, Eduardo de; et al.; Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro; Japanese Circulation Soc; Circulation Journal; 74; 5; 3-2010; 1014-10221346-98431347-4820CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.jstage.jst.go.jp/article/circj/74/5/74_CJ-09-0496/_articleinfo:eu-repo/semantics/altIdentifier/doi/10.1253/circj.CJ-09-0496info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-03-31T15:05:20Zoai:ri.conicet.gov.ar:11336/280208instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-03-31 15:05:20.974CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
title Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
spellingShingle Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
Cabrera Fischer, Edmundo Ignacio
ADVENTITIA
ARTERIAL CONDUIT FUNCTION
ARTERIAL STIFFNESS
ELASTIC ARTERIES
title_short Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
title_full Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
title_fullStr Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
title_full_unstemmed Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
title_sort Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
dc.creator.none.fl_str_mv Cabrera Fischer, Edmundo Ignacio
Santana, Daniel Bia
Zócalo, Yanina
Camus, Juan Manuel
Forteza, Eduardo de
Armentano, Ricardo Luis
author Cabrera Fischer, Edmundo Ignacio
author_facet Cabrera Fischer, Edmundo Ignacio
Santana, Daniel Bia
Zócalo, Yanina
Camus, Juan Manuel
Forteza, Eduardo de
Armentano, Ricardo Luis
author_role author
author2 Santana, Daniel Bia
Zócalo, Yanina
Camus, Juan Manuel
Forteza, Eduardo de
Armentano, Ricardo Luis
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ADVENTITIA
ARTERIAL CONDUIT FUNCTION
ARTERIAL STIFFNESS
ELASTIC ARTERIES
topic ADVENTITIA
ARTERIAL CONDUIT FUNCTION
ARTERIAL STIFFNESS
ELASTIC ARTERIES
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.6
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Background: The aims were to characterize in muscular arteries (a) the passive and active effects of the adventitia on vessel biomechanical properties and conduit function (CF), and (b) potential differences between the adventitial role in elastic and muscular arteries. Methods and Results: Ovine femoral arteries were studied in vivo and in vitro (reduced smooth muscle-tone) in a circulation mock-up during hemodynamic conditions similar to those found in vivo. Pressure and diameter were assessed before and after removing the adventitia. The arterial compliance, distensibility, stiffness β-index and CF were quantified. Results were compared with those obtained in brachiocephalic trunks. In vivo, after removing the adventitia there was a nonsignificant diameter reduction and an increase in stiffness (P<0.05). The CF decreased in the early recordings (P<0.02). In vitro, there were no biomechanical changes but vascular dilatation after the adventitia removal. Biomechanical changes associated with the adventitia removal were higher in muscular arteries, whereas diameter changes were major in elastic vessels. Conclusions: After removing the adventitia, (a) the arterial stiffness and CF were modified in vivo only, suggesting the changes could be ascribed to variations in smooth muscle tone, and (b) changes in elastic and muscular arteries were quantitatively different. (Circ J 2010; 74: 1014 - 1022).
Fil: Cabrera Fischer, Edmundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina
Fil: Santana, Daniel Bia. Universidad de la República; Uruguay
Fil: Zócalo, Yanina. Universidad de la República; Uruguay
Fil: Camus, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina. Universidad de Mendoza; Argentina
Fil: Forteza, Eduardo de. Universidad Favaloro; Argentina
Fil: Armentano, Ricardo Luis. Universidad Favaloro; Argentina. Universidad de la República; Uruguay
description Background: The aims were to characterize in muscular arteries (a) the passive and active effects of the adventitia on vessel biomechanical properties and conduit function (CF), and (b) potential differences between the adventitial role in elastic and muscular arteries. Methods and Results: Ovine femoral arteries were studied in vivo and in vitro (reduced smooth muscle-tone) in a circulation mock-up during hemodynamic conditions similar to those found in vivo. Pressure and diameter were assessed before and after removing the adventitia. The arterial compliance, distensibility, stiffness β-index and CF were quantified. Results were compared with those obtained in brachiocephalic trunks. In vivo, after removing the adventitia there was a nonsignificant diameter reduction and an increase in stiffness (P<0.05). The CF decreased in the early recordings (P<0.02). In vitro, there were no biomechanical changes but vascular dilatation after the adventitia removal. Biomechanical changes associated with the adventitia removal were higher in muscular arteries, whereas diameter changes were major in elastic vessels. Conclusions: After removing the adventitia, (a) the arterial stiffness and CF were modified in vivo only, suggesting the changes could be ascribed to variations in smooth muscle tone, and (b) changes in elastic and muscular arteries were quantitatively different. (Circ J 2010; 74: 1014 - 1022).
publishDate 2010
dc.date.none.fl_str_mv 2010-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/280208
Cabrera Fischer, Edmundo Ignacio; Santana, Daniel Bia; Zócalo, Yanina; Camus, Juan Manuel; Forteza, Eduardo de; et al.; Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro; Japanese Circulation Soc; Circulation Journal; 74; 5; 3-2010; 1014-1022
1346-9843
1347-4820
CONICET Digital
CONICET
url http://hdl.handle.net/11336/280208
identifier_str_mv Cabrera Fischer, Edmundo Ignacio; Santana, Daniel Bia; Zócalo, Yanina; Camus, Juan Manuel; Forteza, Eduardo de; et al.; Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro; Japanese Circulation Soc; Circulation Journal; 74; 5; 3-2010; 1014-1022
1346-9843
1347-4820
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.jstage.jst.go.jp/article/circj/74/5/74_CJ-09-0496/_article
info:eu-repo/semantics/altIdentifier/doi/10.1253/circj.CJ-09-0496
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Japanese Circulation Soc
publisher.none.fl_str_mv Japanese Circulation Soc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1861214266249445376
score 12.822162

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