Oxidation of sodium alginate and characterization of the oxidized derivatives
- Autores
- Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando
- Año de publicación
- 2007
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units.
Fil: Gomez, Cesar G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Rinaudo, Marguerite. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Villar, Marcelo Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina - Materia
-
ALGINATES
BIOPOLYMERS
HYDROGELS
OXIDATION
SODIUM PERIODATE - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/136573
Ver los metadatos del registro completo
id |
CONICETDig_b5214a3c3f5e58ec49d2f999760a3e9e |
---|---|
oai_identifier_str |
oai:ri.conicet.gov.ar:11336/136573 |
network_acronym_str |
CONICETDig |
repository_id_str |
3498 |
network_name_str |
CONICET Digital (CONICET) |
spelling |
Oxidation of sodium alginate and characterization of the oxidized derivativesGomez, Cesar G.Rinaudo, MargueriteVillar, Marcelo ArmandoALGINATESBIOPOLYMERSHYDROGELSOXIDATIONSODIUM PERIODATEhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units.Fil: Gomez, Cesar G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; FranciaFil: Rinaudo, Marguerite. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; FranciaFil: Villar, Marcelo Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaElsevier2007-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/136573Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando; Oxidation of sodium alginate and characterization of the oxidized derivatives; Elsevier; Carbohydrate Polymers; 67; 3; 1-2-2007; 296-3040144-8617CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.carbpol.2006.05.025info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0144861706002761info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:09:31Zoai:ri.conicet.gov.ar:11336/136573instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:09:31.297CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
title |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
spellingShingle |
Oxidation of sodium alginate and characterization of the oxidized derivatives Gomez, Cesar G. ALGINATES BIOPOLYMERS HYDROGELS OXIDATION SODIUM PERIODATE |
title_short |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
title_full |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
title_fullStr |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
title_full_unstemmed |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
title_sort |
Oxidation of sodium alginate and characterization of the oxidized derivatives |
dc.creator.none.fl_str_mv |
Gomez, Cesar G. Rinaudo, Marguerite Villar, Marcelo Armando |
author |
Gomez, Cesar G. |
author_facet |
Gomez, Cesar G. Rinaudo, Marguerite Villar, Marcelo Armando |
author_role |
author |
author2 |
Rinaudo, Marguerite Villar, Marcelo Armando |
author2_role |
author author |
dc.subject.none.fl_str_mv |
ALGINATES BIOPOLYMERS HYDROGELS OXIDATION SODIUM PERIODATE |
topic |
ALGINATES BIOPOLYMERS HYDROGELS OXIDATION SODIUM PERIODATE |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/2.4 https://purl.org/becyt/ford/2 |
dc.description.none.fl_txt_mv |
Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units. Fil: Gomez, Cesar G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia Fil: Rinaudo, Marguerite. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia Fil: Villar, Marcelo Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina |
description |
Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-02-01 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/136573 Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando; Oxidation of sodium alginate and characterization of the oxidized derivatives; Elsevier; Carbohydrate Polymers; 67; 3; 1-2-2007; 296-304 0144-8617 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/136573 |
identifier_str_mv |
Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando; Oxidation of sodium alginate and characterization of the oxidized derivatives; Elsevier; Carbohydrate Polymers; 67; 3; 1-2-2007; 296-304 0144-8617 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.carbpol.2006.05.025 info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0144861706002761 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
_version_ |
1844613974642917376 |
score |
13.070432 |