Oxidation of sodium alginate and characterization of the oxidized derivatives

Autores
Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando
Año de publicación
2007
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units.
Fil: Gomez, Cesar G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Rinaudo, Marguerite. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Villar, Marcelo Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Materia
ALGINATES
BIOPOLYMERS
HYDROGELS
OXIDATION
SODIUM PERIODATE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/136573
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/136573
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Oxidation of sodium alginate and characterization of the oxidized derivativesGomez, Cesar G.Rinaudo, MargueriteVillar, Marcelo ArmandoALGINATESBIOPOLYMERSHYDROGELSOXIDATIONSODIUM PERIODATEhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units.Fil: Gomez, Cesar G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; FranciaFil: Rinaudo, Marguerite. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; FranciaFil: Villar, Marcelo Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaElsevier2007-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/136573Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando; Oxidation of sodium alginate and characterization of the oxidized derivatives; Elsevier; Carbohydrate Polymers; 67; 3; 1-2-2007; 296-3040144-8617CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.carbpol.2006.05.025info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0144861706002761info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:39:24Zoai:ri.conicet.gov.ar:11336/136573instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:39:24.508CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Oxidation of sodium alginate and characterization of the oxidized derivatives
title Oxidation of sodium alginate and characterization of the oxidized derivatives
spellingShingle Oxidation of sodium alginate and characterization of the oxidized derivatives
Gomez, Cesar G.
ALGINATES
BIOPOLYMERS
HYDROGELS
OXIDATION
SODIUM PERIODATE
title_short Oxidation of sodium alginate and characterization of the oxidized derivatives
title_full Oxidation of sodium alginate and characterization of the oxidized derivatives
title_fullStr Oxidation of sodium alginate and characterization of the oxidized derivatives
title_full_unstemmed Oxidation of sodium alginate and characterization of the oxidized derivatives
title_sort Oxidation of sodium alginate and characterization of the oxidized derivatives
dc.creator.none.fl_str_mv Gomez, Cesar G.
Rinaudo, Marguerite
Villar, Marcelo Armando
author Gomez, Cesar G.
author_facet Gomez, Cesar G.
Rinaudo, Marguerite
Villar, Marcelo Armando
author_role author
author2 Rinaudo, Marguerite
Villar, Marcelo Armando
author2_role author
author
dc.subject.none.fl_str_mv ALGINATES
BIOPOLYMERS
HYDROGELS
OXIDATION
SODIUM PERIODATE
topic ALGINATES
BIOPOLYMERS
HYDROGELS
OXIDATION
SODIUM PERIODATE
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units.
Fil: Gomez, Cesar G.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Rinaudo, Marguerite. Universite Joseph Fourier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Villar, Marcelo Armando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
description Oxidation reactions on -OH groups at C-2 and C-3 positions of the uronic units of sodium alginate were performed with sodium periodate, and the influence of degree of oxidation on physical properties of the oxidized derivatives was analyzed. The aim of this work was to find new active functional groups on alginates, which is a polymer of interest as support in drug-controlled delivery systems. The molar mass decreases rapidly until an oxidation of 10 mol% and then remains nearly constant. Polymers with a degree of oxidation higher than 10 mol% were no more able to form gels with calcium ions. Both elastic modulus (G′) and swelling degree (SD) of alginate gels decrease as the degree of oxidation increases. This behavior was attributed to the decreasing in the cooperative interactions between calcium ions and carboxylate groups due to a decrease in both the molar mass and the number of unreacted G units.
publishDate 2007
dc.date.none.fl_str_mv 2007-02-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/136573
Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando; Oxidation of sodium alginate and characterization of the oxidized derivatives; Elsevier; Carbohydrate Polymers; 67; 3; 1-2-2007; 296-304
0144-8617
CONICET Digital
CONICET
url http://hdl.handle.net/11336/136573
identifier_str_mv Gomez, Cesar G.; Rinaudo, Marguerite; Villar, Marcelo Armando; Oxidation of sodium alginate and characterization of the oxidized derivatives; Elsevier; Carbohydrate Polymers; 67; 3; 1-2-2007; 296-304
0144-8617
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.carbpol.2006.05.025
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0144861706002761
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.229304

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