Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata

Autores
Roggio, María Angelina; Guyón, Noelia Fernanda; Hued, Andrea Cecilia; Amé, María Valeria; Valdés, María Eugenia; Giojalas, Laura Cecilia; Wunderlin, Daniel Alberto; Bistoni, M. A.
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The synthetic estrogen 17a-ethynylestradiol (EE2) has been increasingly detected in sewage effluents in the last two decades. The aim of the present study was determined if EE2 exposure adversely affected reproduction in internally fertilizing fish species Jenynsia multidentata. Sexual behavior, brain and gonadal aromatase expression as well as sperm quality were evaluated. The brain aromatase expression, reproductive behavior, spermatozoa viability and gonadosomatic index were sensitive biomarkers of EE2 effects on this species. The condition factor, hepatosomatic index, gonadal aromatase expression, sperm count and sperm velocities were unaltered after EE2 exposure. The present work highlights the importance of using a combination of several biomarkers to study the effects of estrogenic compounds, especially when trying to link these results to potential population-level effects.
Fil: Roggio, María Angelina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Guyón, Noelia Fernanda. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Hued, Andrea Cecilia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Amé, María Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones En Bioquímica Clínica E Inmunología; Argentina
Fil: Valdés, María Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Giojalas, Laura Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Biología Celular y Molecular; Argentina
Fil: Wunderlin, Daniel Alberto. Universidad Nacional de Cordoba. Secretaria de Ciencia y Tecnologia. Instituto Sup.de Inv., Desarrollo y Serv.de Alimentos; Argentina
Fil: Bistoni, M. A.. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Materia
Estrogens
Endocrine Disruptors
Fish
Water
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/7946
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/7946
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentataRoggio, María AngelinaGuyón, Noelia FernandaHued, Andrea CeciliaAmé, María ValeriaValdés, María EugeniaGiojalas, Laura CeciliaWunderlin, Daniel AlbertoBistoni, M. A.EstrogensEndocrine DisruptorsFishWaterhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The synthetic estrogen 17a-ethynylestradiol (EE2) has been increasingly detected in sewage effluents in the last two decades. The aim of the present study was determined if EE2 exposure adversely affected reproduction in internally fertilizing fish species Jenynsia multidentata. Sexual behavior, brain and gonadal aromatase expression as well as sperm quality were evaluated. The brain aromatase expression, reproductive behavior, spermatozoa viability and gonadosomatic index were sensitive biomarkers of EE2 effects on this species. The condition factor, hepatosomatic index, gonadal aromatase expression, sperm count and sperm velocities were unaltered after EE2 exposure. The present work highlights the importance of using a combination of several biomarkers to study the effects of estrogenic compounds, especially when trying to link these results to potential population-level effects.Fil: Roggio, María Angelina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Guyón, Noelia Fernanda. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Hued, Andrea Cecilia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Amé, María Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones En Bioquímica Clínica E Inmunología; ArgentinaFil: Valdés, María Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Giojalas, Laura Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Biología Celular y Molecular; ArgentinaFil: Wunderlin, Daniel Alberto. Universidad Nacional de Cordoba. Secretaria de Ciencia y Tecnologia. Instituto Sup.de Inv., Desarrollo y Serv.de Alimentos; ArgentinaFil: Bistoni, M. A.. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; ArgentinaSpringer2014-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/7946Roggio, María Angelina; Guyón, Noelia Fernanda; Hued, Andrea Cecilia; Amé, María Valeria; Valdés, María Eugenia; et al.; Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata; Springer; Bulletin Of Environmental Contamination And Toxicology; 92; 5; 1-2014; 579–5840007-4861enginfo:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007/s00128-013-1185-2info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-013-1185-2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:55:02Zoai:ri.conicet.gov.ar:11336/7946instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:55:02.833CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
title Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
spellingShingle Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
Roggio, María Angelina
Estrogens
Endocrine Disruptors
Fish
Water
title_short Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
title_full Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
title_fullStr Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
title_full_unstemmed Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
title_sort Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata
dc.creator.none.fl_str_mv Roggio, María Angelina
Guyón, Noelia Fernanda
Hued, Andrea Cecilia
Amé, María Valeria
Valdés, María Eugenia
Giojalas, Laura Cecilia
Wunderlin, Daniel Alberto
Bistoni, M. A.
author Roggio, María Angelina
author_facet Roggio, María Angelina
Guyón, Noelia Fernanda
Hued, Andrea Cecilia
Amé, María Valeria
Valdés, María Eugenia
Giojalas, Laura Cecilia
Wunderlin, Daniel Alberto
Bistoni, M. A.
author_role author
author2 Guyón, Noelia Fernanda
Hued, Andrea Cecilia
Amé, María Valeria
Valdés, María Eugenia
Giojalas, Laura Cecilia
Wunderlin, Daniel Alberto
Bistoni, M. A.
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Estrogens
Endocrine Disruptors
Fish
Water
topic Estrogens
Endocrine Disruptors
Fish
Water
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The synthetic estrogen 17a-ethynylestradiol (EE2) has been increasingly detected in sewage effluents in the last two decades. The aim of the present study was determined if EE2 exposure adversely affected reproduction in internally fertilizing fish species Jenynsia multidentata. Sexual behavior, brain and gonadal aromatase expression as well as sperm quality were evaluated. The brain aromatase expression, reproductive behavior, spermatozoa viability and gonadosomatic index were sensitive biomarkers of EE2 effects on this species. The condition factor, hepatosomatic index, gonadal aromatase expression, sperm count and sperm velocities were unaltered after EE2 exposure. The present work highlights the importance of using a combination of several biomarkers to study the effects of estrogenic compounds, especially when trying to link these results to potential population-level effects.
Fil: Roggio, María Angelina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Guyón, Noelia Fernanda. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Hued, Andrea Cecilia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Amé, María Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones En Bioquímica Clínica E Inmunología; Argentina
Fil: Valdés, María Eugenia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
Fil: Giojalas, Laura Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Biología Celular y Molecular; Argentina
Fil: Wunderlin, Daniel Alberto. Universidad Nacional de Cordoba. Secretaria de Ciencia y Tecnologia. Instituto Sup.de Inv., Desarrollo y Serv.de Alimentos; Argentina
Fil: Bistoni, M. A.. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Cordoba. Instituto de Diversidad y Ecologia Animal; Argentina. Universidad Nacional de Córdoba; Argentina
description The synthetic estrogen 17a-ethynylestradiol (EE2) has been increasingly detected in sewage effluents in the last two decades. The aim of the present study was determined if EE2 exposure adversely affected reproduction in internally fertilizing fish species Jenynsia multidentata. Sexual behavior, brain and gonadal aromatase expression as well as sperm quality were evaluated. The brain aromatase expression, reproductive behavior, spermatozoa viability and gonadosomatic index were sensitive biomarkers of EE2 effects on this species. The condition factor, hepatosomatic index, gonadal aromatase expression, sperm count and sperm velocities were unaltered after EE2 exposure. The present work highlights the importance of using a combination of several biomarkers to study the effects of estrogenic compounds, especially when trying to link these results to potential population-level effects.
publishDate 2014
dc.date.none.fl_str_mv 2014-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/7946
Roggio, María Angelina; Guyón, Noelia Fernanda; Hued, Andrea Cecilia; Amé, María Valeria; Valdés, María Eugenia; et al.; Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata; Springer; Bulletin Of Environmental Contamination And Toxicology; 92; 5; 1-2014; 579–584
0007-4861
url http://hdl.handle.net/11336/7946
identifier_str_mv Roggio, María Angelina; Guyón, Noelia Fernanda; Hued, Andrea Cecilia; Amé, María Valeria; Valdés, María Eugenia; et al.; Effects of the synthetic estrogen 17α- Ethinylestradiol on aromatase expression, reproductive behavior and sperm quality in the fish Jenynsia multidentata; Springer; Bulletin Of Environmental Contamination And Toxicology; 92; 5; 1-2014; 579–584
0007-4861
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://link.springer.com/article/10.1007/s00128-013-1185-2
info:eu-repo/semantics/altIdentifier/doi/10.1007/s00128-013-1185-2
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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