Fasciola hepatica products induce apoptosis of peritoneal macrophages

Autores
Guasconi, Lorena; Serradell, Marianela del Carmen.; Masih, Diana Teresa
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Immunomodulatory properties have been described for Fasciola hepatica excretory-secretory products (FhESP), with their interaction with the innate immune cells being crucial during the early stages of infection. Previously, we demonstrated that FhESP induce eosinophil apoptosis. In this work, the ability of FhESP to induce apoptosis of peritoneal macrophages was evaluated.These parasite products were observed to induce apoptosis in peritoneal macrophages stimulated in vitro with FhESP, as well as in cells recovered from infected mice. The ability of FhESP to modify the viability of macrophages by apoptosis induction may constitute a crucial event for extending its survival in the host. © 2012 Elsevier B.V.
Fil: Guasconi, Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Serradell, Marianela del Carmen.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas. Universidad Católica de Córdoba. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas; Argentina
Fil: Masih, Diana Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Materia
Apoptosis
Excretory-Secretory Products
Fasciola Hepatica
Infection
Peritoneal Macrophages
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/54952
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Fasciola hepatica products induce apoptosis of peritoneal macrophagesGuasconi, LorenaSerradell, Marianela del Carmen.Masih, Diana TeresaApoptosisExcretory-Secretory ProductsFasciola HepaticaInfectionPeritoneal Macrophageshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Immunomodulatory properties have been described for Fasciola hepatica excretory-secretory products (FhESP), with their interaction with the innate immune cells being crucial during the early stages of infection. Previously, we demonstrated that FhESP induce eosinophil apoptosis. In this work, the ability of FhESP to induce apoptosis of peritoneal macrophages was evaluated.These parasite products were observed to induce apoptosis in peritoneal macrophages stimulated in vitro with FhESP, as well as in cells recovered from infected mice. The ability of FhESP to modify the viability of macrophages by apoptosis induction may constitute a crucial event for extending its survival in the host. © 2012 Elsevier B.V.Fil: Guasconi, Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Serradell, Marianela del Carmen.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas. Universidad Católica de Córdoba. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas; ArgentinaFil: Masih, Diana Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaElsevier Science2012-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/54952Guasconi, Lorena; Serradell, Marianela del Carmen.; Masih, Diana Teresa; Fasciola hepatica products induce apoptosis of peritoneal macrophages; Elsevier Science; Veterinary Immunology And Immunopathology; 148; 3-4; 8-2012; 359-3630165-2427CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165242712002152info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetimm.2012.06.022info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:10:17Zoai:ri.conicet.gov.ar:11336/54952instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:10:17.581CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Fasciola hepatica products induce apoptosis of peritoneal macrophages
title Fasciola hepatica products induce apoptosis of peritoneal macrophages
spellingShingle Fasciola hepatica products induce apoptosis of peritoneal macrophages
Guasconi, Lorena
Apoptosis
Excretory-Secretory Products
Fasciola Hepatica
Infection
Peritoneal Macrophages
title_short Fasciola hepatica products induce apoptosis of peritoneal macrophages
title_full Fasciola hepatica products induce apoptosis of peritoneal macrophages
title_fullStr Fasciola hepatica products induce apoptosis of peritoneal macrophages
title_full_unstemmed Fasciola hepatica products induce apoptosis of peritoneal macrophages
title_sort Fasciola hepatica products induce apoptosis of peritoneal macrophages
dc.creator.none.fl_str_mv Guasconi, Lorena
Serradell, Marianela del Carmen.
Masih, Diana Teresa
author Guasconi, Lorena
author_facet Guasconi, Lorena
Serradell, Marianela del Carmen.
Masih, Diana Teresa
author_role author
author2 Serradell, Marianela del Carmen.
Masih, Diana Teresa
author2_role author
author
dc.subject.none.fl_str_mv Apoptosis
Excretory-Secretory Products
Fasciola Hepatica
Infection
Peritoneal Macrophages
topic Apoptosis
Excretory-Secretory Products
Fasciola Hepatica
Infection
Peritoneal Macrophages
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Immunomodulatory properties have been described for Fasciola hepatica excretory-secretory products (FhESP), with their interaction with the innate immune cells being crucial during the early stages of infection. Previously, we demonstrated that FhESP induce eosinophil apoptosis. In this work, the ability of FhESP to induce apoptosis of peritoneal macrophages was evaluated.These parasite products were observed to induce apoptosis in peritoneal macrophages stimulated in vitro with FhESP, as well as in cells recovered from infected mice. The ability of FhESP to modify the viability of macrophages by apoptosis induction may constitute a crucial event for extending its survival in the host. © 2012 Elsevier B.V.
Fil: Guasconi, Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
Fil: Serradell, Marianela del Carmen.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas. Universidad Católica de Córdoba. Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas; Argentina
Fil: Masih, Diana Teresa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
description Immunomodulatory properties have been described for Fasciola hepatica excretory-secretory products (FhESP), with their interaction with the innate immune cells being crucial during the early stages of infection. Previously, we demonstrated that FhESP induce eosinophil apoptosis. In this work, the ability of FhESP to induce apoptosis of peritoneal macrophages was evaluated.These parasite products were observed to induce apoptosis in peritoneal macrophages stimulated in vitro with FhESP, as well as in cells recovered from infected mice. The ability of FhESP to modify the viability of macrophages by apoptosis induction may constitute a crucial event for extending its survival in the host. © 2012 Elsevier B.V.
publishDate 2012
dc.date.none.fl_str_mv 2012-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/54952
Guasconi, Lorena; Serradell, Marianela del Carmen.; Masih, Diana Teresa; Fasciola hepatica products induce apoptosis of peritoneal macrophages; Elsevier Science; Veterinary Immunology And Immunopathology; 148; 3-4; 8-2012; 359-363
0165-2427
CONICET Digital
CONICET
url http://hdl.handle.net/11336/54952
identifier_str_mv Guasconi, Lorena; Serradell, Marianela del Carmen.; Masih, Diana Teresa; Fasciola hepatica products induce apoptosis of peritoneal macrophages; Elsevier Science; Veterinary Immunology And Immunopathology; 148; 3-4; 8-2012; 359-363
0165-2427
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165242712002152
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetimm.2012.06.022
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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