Genetically transformed roots: From plant disease to biotechnological resource

Autores
Georgiev, Milen I.; Agostini, Elizabeth; Ludwig Müller, Jutta; Xu, Jianfeng
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and characterized by a proliferation of excessively branching roots. However, in the past 30 years A. rhizogenes-mediated transformation has also provided a valuable platform for studying biosynthesis pathways in plants. Furthermore, the genetically transformed root cultures are becoming increasingly attractive, cost-effective options for mass-producing desired plant metabolites and expressing foreign proteins. Numerous proof-of-concept studies have demonstrated the feasibility of scaling up hairy-root-based processes while maintaining their biosynthetic potential. Recently, hairy roots have also shown immense potential for applications in phytoremediation, that is, plant-based decontamination of polluted environments. This review highlights recent progress and limitations in the field, and outlines future perspectives for the industrial exploitation of hairy roots.
Fil: Georgiev, Milen I.. Bulgarian Academy of Sciences; Bulgaria. Leiden University; Países Bajos
Fil: Agostini, Elizabeth. Universidad Nacional de Río Cuarto; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Ludwig Müller, Jutta. Technische Universitat Dresden; Alemania
Fil: Xu, Jianfeng. University of Arkansas for Medical Sciences; Estados Unidos
Materia
HAIRY ROOT
PHYTOREMEDIATION
SECONDARY METABOLITES
BIOREACTOR
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/198040
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Genetically transformed roots: From plant disease to biotechnological resourceGeorgiev, Milen I.Agostini, ElizabethLudwig Müller, JuttaXu, JianfengHAIRY ROOTPHYTOREMEDIATIONSECONDARY METABOLITESBIOREACTORhttps://purl.org/becyt/ford/2.8https://purl.org/becyt/ford/2Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and characterized by a proliferation of excessively branching roots. However, in the past 30 years A. rhizogenes-mediated transformation has also provided a valuable platform for studying biosynthesis pathways in plants. Furthermore, the genetically transformed root cultures are becoming increasingly attractive, cost-effective options for mass-producing desired plant metabolites and expressing foreign proteins. Numerous proof-of-concept studies have demonstrated the feasibility of scaling up hairy-root-based processes while maintaining their biosynthetic potential. Recently, hairy roots have also shown immense potential for applications in phytoremediation, that is, plant-based decontamination of polluted environments. This review highlights recent progress and limitations in the field, and outlines future perspectives for the industrial exploitation of hairy roots.Fil: Georgiev, Milen I.. Bulgarian Academy of Sciences; Bulgaria. Leiden University; Países BajosFil: Agostini, Elizabeth. Universidad Nacional de Río Cuarto; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Ludwig Müller, Jutta. Technische Universitat Dresden; AlemaniaFil: Xu, Jianfeng. University of Arkansas for Medical Sciences; Estados UnidosElsevier Science London2012-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/198040Georgiev, Milen I.; Agostini, Elizabeth; Ludwig Müller, Jutta; Xu, Jianfeng; Genetically transformed roots: From plant disease to biotechnological resource; Elsevier Science London; Trends In Biotechnology; 30; 10; 8-2012; 528-5370167-7799CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0167779912001084info:eu-repo/semantics/altIdentifier/doi/10.1016/j.tibtech.2012.07.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-26T08:56:25Zoai:ri.conicet.gov.ar:11336/198040instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-26 08:56:25.767CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Genetically transformed roots: From plant disease to biotechnological resource
title Genetically transformed roots: From plant disease to biotechnological resource
spellingShingle Genetically transformed roots: From plant disease to biotechnological resource
Georgiev, Milen I.
HAIRY ROOT
PHYTOREMEDIATION
SECONDARY METABOLITES
BIOREACTOR
title_short Genetically transformed roots: From plant disease to biotechnological resource
title_full Genetically transformed roots: From plant disease to biotechnological resource
title_fullStr Genetically transformed roots: From plant disease to biotechnological resource
title_full_unstemmed Genetically transformed roots: From plant disease to biotechnological resource
title_sort Genetically transformed roots: From plant disease to biotechnological resource
dc.creator.none.fl_str_mv Georgiev, Milen I.
Agostini, Elizabeth
Ludwig Müller, Jutta
Xu, Jianfeng
author Georgiev, Milen I.
author_facet Georgiev, Milen I.
Agostini, Elizabeth
Ludwig Müller, Jutta
Xu, Jianfeng
author_role author
author2 Agostini, Elizabeth
Ludwig Müller, Jutta
Xu, Jianfeng
author2_role author
author
author
dc.subject.none.fl_str_mv HAIRY ROOT
PHYTOREMEDIATION
SECONDARY METABOLITES
BIOREACTOR
topic HAIRY ROOT
PHYTOREMEDIATION
SECONDARY METABOLITES
BIOREACTOR
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.8
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and characterized by a proliferation of excessively branching roots. However, in the past 30 years A. rhizogenes-mediated transformation has also provided a valuable platform for studying biosynthesis pathways in plants. Furthermore, the genetically transformed root cultures are becoming increasingly attractive, cost-effective options for mass-producing desired plant metabolites and expressing foreign proteins. Numerous proof-of-concept studies have demonstrated the feasibility of scaling up hairy-root-based processes while maintaining their biosynthetic potential. Recently, hairy roots have also shown immense potential for applications in phytoremediation, that is, plant-based decontamination of polluted environments. This review highlights recent progress and limitations in the field, and outlines future perspectives for the industrial exploitation of hairy roots.
Fil: Georgiev, Milen I.. Bulgarian Academy of Sciences; Bulgaria. Leiden University; Países Bajos
Fil: Agostini, Elizabeth. Universidad Nacional de Río Cuarto; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Ludwig Müller, Jutta. Technische Universitat Dresden; Alemania
Fil: Xu, Jianfeng. University of Arkansas for Medical Sciences; Estados Unidos
description Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and characterized by a proliferation of excessively branching roots. However, in the past 30 years A. rhizogenes-mediated transformation has also provided a valuable platform for studying biosynthesis pathways in plants. Furthermore, the genetically transformed root cultures are becoming increasingly attractive, cost-effective options for mass-producing desired plant metabolites and expressing foreign proteins. Numerous proof-of-concept studies have demonstrated the feasibility of scaling up hairy-root-based processes while maintaining their biosynthetic potential. Recently, hairy roots have also shown immense potential for applications in phytoremediation, that is, plant-based decontamination of polluted environments. This review highlights recent progress and limitations in the field, and outlines future perspectives for the industrial exploitation of hairy roots.
publishDate 2012
dc.date.none.fl_str_mv 2012-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/198040
Georgiev, Milen I.; Agostini, Elizabeth; Ludwig Müller, Jutta; Xu, Jianfeng; Genetically transformed roots: From plant disease to biotechnological resource; Elsevier Science London; Trends In Biotechnology; 30; 10; 8-2012; 528-537
0167-7799
CONICET Digital
CONICET
url http://hdl.handle.net/11336/198040
identifier_str_mv Georgiev, Milen I.; Agostini, Elizabeth; Ludwig Müller, Jutta; Xu, Jianfeng; Genetically transformed roots: From plant disease to biotechnological resource; Elsevier Science London; Trends In Biotechnology; 30; 10; 8-2012; 528-537
0167-7799
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0167779912001084
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.tibtech.2012.07.001
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science London
publisher.none.fl_str_mv Elsevier Science London
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.011256

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