Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study

Autores
Rivadeneira Paz, Pablo Santiago; Moog, Claude; Stan, Guy Bart; Costanza, Vicente; Brunet, Cecile; Raffi, Francois; Ferré, Virginie; Mhawej, Marie José; Biafore, Federico Leonardo; Ouattara, Djomangan; Ernst, Damien; Fonteneau, Raphael; Xia, Xiaohua
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Immunological failure is identified from the estimation of certain parameters of a mathematical model of HIV infection dynamics. This identification is supported by clinical research results from an original clinical trial. Standard clinical data were collected from infected patients starting highly active antiretroviral therapy (HAART) after just 1 month of therapy initiation and were used to carry out the model identification. The early diagnosis is shown to be consistent with patient monitoring after 6 months.
Fil: Rivadeneira Paz, Pablo Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); Argentina
Fil: Moog, Claude. Centre National de la Recherche Scientifique; Francia
Fil: Stan, Guy Bart. Imperial College London; Reino Unido
Fil: Costanza, Vicente. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); Argentina
Fil: Brunet, Cecile. Universite de Nantes; Francia
Fil: Raffi, Francois. Universite de Nantes; Francia
Fil: Ferré, Virginie. Universite de Nantes; Francia
Fil: Mhawej, Marie José. Centre National de la Recherche Scientifique; Francia
Fil: Biafore, Federico Leonardo. Universidad Nacional de San Martin. Escuela de Ciencia y Tecnologia. Centro de Matematica Aplicada; Argentina
Fil: Ouattara, Djomangan. Universite de Nantes; Francia
Fil: Ernst, Damien. Universite de Liege; Bélgica
Fil: Fonteneau, Raphael. Universite de Liege; Bélgica
Fil: Xia, Xiaohua. University of Pretoria; Sudáfrica
Materia
Hiv
Apoptosis
Immunological Failure
Early Diagnosis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/9264
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research StudyRivadeneira Paz, Pablo SantiagoMoog, ClaudeStan, Guy BartCostanza, VicenteBrunet, CecileRaffi, FrancoisFerré, VirginieMhawej, Marie JoséBiafore, Federico LeonardoOuattara, DjomanganErnst, DamienFonteneau, RaphaelXia, XiaohuaHivApoptosisImmunological FailureEarly Diagnosishttps://purl.org/becyt/ford/3.4https://purl.org/becyt/ford/3Immunological failure is identified from the estimation of certain parameters of a mathematical model of HIV infection dynamics. This identification is supported by clinical research results from an original clinical trial. Standard clinical data were collected from infected patients starting highly active antiretroviral therapy (HAART) after just 1 month of therapy initiation and were used to carry out the model identification. The early diagnosis is shown to be consistent with patient monitoring after 6 months.Fil: Rivadeneira Paz, Pablo Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); ArgentinaFil: Moog, Claude. Centre National de la Recherche Scientifique; FranciaFil: Stan, Guy Bart. Imperial College London; Reino UnidoFil: Costanza, Vicente. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); ArgentinaFil: Brunet, Cecile. Universite de Nantes; FranciaFil: Raffi, Francois. Universite de Nantes; FranciaFil: Ferré, Virginie. Universite de Nantes; FranciaFil: Mhawej, Marie José. Centre National de la Recherche Scientifique; FranciaFil: Biafore, Federico Leonardo. Universidad Nacional de San Martin. Escuela de Ciencia y Tecnologia. Centro de Matematica Aplicada; ArgentinaFil: Ouattara, Djomangan. Universite de Nantes; FranciaFil: Ernst, Damien. Universite de Liege; BélgicaFil: Fonteneau, Raphael. Universite de Liege; BélgicaFil: Xia, Xiaohua. University of Pretoria; SudáfricaMary Ann Liebert Inc2014-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/9264Rivadeneira Paz, Pablo Santiago; Moog, Claude; Stan, Guy Bart; Costanza, Vicente; Brunet, Cecile; et al.; Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study; Mary Ann Liebert Inc; Aids Research And Human Retroviruses; 30; 9; 9-2014; 831-8340889-2229enginfo:eu-repo/semantics/altIdentifier/doi/10.1089/aid.2013.0286info:eu-repo/semantics/altIdentifier/url/http://online.liebertpub.com/doi/abs/10.1089/aid.2013.0286info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:47:51Zoai:ri.conicet.gov.ar:11336/9264instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:47:51.31CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
title Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
spellingShingle Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
Rivadeneira Paz, Pablo Santiago
Hiv
Apoptosis
Immunological Failure
Early Diagnosis
title_short Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
title_full Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
title_fullStr Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
title_full_unstemmed Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
title_sort Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study
dc.creator.none.fl_str_mv Rivadeneira Paz, Pablo Santiago
Moog, Claude
Stan, Guy Bart
Costanza, Vicente
Brunet, Cecile
Raffi, Francois
Ferré, Virginie
Mhawej, Marie José
Biafore, Federico Leonardo
Ouattara, Djomangan
Ernst, Damien
Fonteneau, Raphael
Xia, Xiaohua
author Rivadeneira Paz, Pablo Santiago
author_facet Rivadeneira Paz, Pablo Santiago
Moog, Claude
Stan, Guy Bart
Costanza, Vicente
Brunet, Cecile
Raffi, Francois
Ferré, Virginie
Mhawej, Marie José
Biafore, Federico Leonardo
Ouattara, Djomangan
Ernst, Damien
Fonteneau, Raphael
Xia, Xiaohua
author_role author
author2 Moog, Claude
Stan, Guy Bart
Costanza, Vicente
Brunet, Cecile
Raffi, Francois
Ferré, Virginie
Mhawej, Marie José
Biafore, Federico Leonardo
Ouattara, Djomangan
Ernst, Damien
Fonteneau, Raphael
Xia, Xiaohua
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Hiv
Apoptosis
Immunological Failure
Early Diagnosis
topic Hiv
Apoptosis
Immunological Failure
Early Diagnosis
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.4
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Immunological failure is identified from the estimation of certain parameters of a mathematical model of HIV infection dynamics. This identification is supported by clinical research results from an original clinical trial. Standard clinical data were collected from infected patients starting highly active antiretroviral therapy (HAART) after just 1 month of therapy initiation and were used to carry out the model identification. The early diagnosis is shown to be consistent with patient monitoring after 6 months.
Fil: Rivadeneira Paz, Pablo Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); Argentina
Fil: Moog, Claude. Centre National de la Recherche Scientifique; Francia
Fil: Stan, Guy Bart. Imperial College London; Reino Unido
Fil: Costanza, Vicente. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); Argentina
Fil: Brunet, Cecile. Universite de Nantes; Francia
Fil: Raffi, Francois. Universite de Nantes; Francia
Fil: Ferré, Virginie. Universite de Nantes; Francia
Fil: Mhawej, Marie José. Centre National de la Recherche Scientifique; Francia
Fil: Biafore, Federico Leonardo. Universidad Nacional de San Martin. Escuela de Ciencia y Tecnologia. Centro de Matematica Aplicada; Argentina
Fil: Ouattara, Djomangan. Universite de Nantes; Francia
Fil: Ernst, Damien. Universite de Liege; Bélgica
Fil: Fonteneau, Raphael. Universite de Liege; Bélgica
Fil: Xia, Xiaohua. University of Pretoria; Sudáfrica
description Immunological failure is identified from the estimation of certain parameters of a mathematical model of HIV infection dynamics. This identification is supported by clinical research results from an original clinical trial. Standard clinical data were collected from infected patients starting highly active antiretroviral therapy (HAART) after just 1 month of therapy initiation and were used to carry out the model identification. The early diagnosis is shown to be consistent with patient monitoring after 6 months.
publishDate 2014
dc.date.none.fl_str_mv 2014-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/9264
Rivadeneira Paz, Pablo Santiago; Moog, Claude; Stan, Guy Bart; Costanza, Vicente; Brunet, Cecile; et al.; Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study; Mary Ann Liebert Inc; Aids Research And Human Retroviruses; 30; 9; 9-2014; 831-834
0889-2229
url http://hdl.handle.net/11336/9264
identifier_str_mv Rivadeneira Paz, Pablo Santiago; Moog, Claude; Stan, Guy Bart; Costanza, Vicente; Brunet, Cecile; et al.; Mathematical Modeling of HIV Dynamics After Antiretroviral Therapy Initiation: A Clinical Research Study; Mary Ann Liebert Inc; Aids Research And Human Retroviruses; 30; 9; 9-2014; 831-834
0889-2229
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1089/aid.2013.0286
info:eu-repo/semantics/altIdentifier/url/http://online.liebertpub.com/doi/abs/10.1089/aid.2013.0286
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Mary Ann Liebert Inc
publisher.none.fl_str_mv Mary Ann Liebert Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082996367523840
score 13.22299

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