Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina

Autores
Andresiuk, Maria Vanesa; Gordo, Francisco Ponce; Saarma, Merilin; Elissondo, María Celina; Taraborelli, Ana; Casalongue, Claudia; Denegri, Guillermo Maria; Saarma, Urmas
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Cystic echinococcosis (hydatidosis) is a severe and widespread disease, caused by the larval stage of the tapeworm Echinococcus granulosus; it affects large numbers of humans and farm animals annually, causing serious health and economic problems. Molecular studies have identified large genetic variation within the E. granulosus complex, with various hosts displaying different susceptibility to different genotypes. For the effective management of the disease, one of the most pressing tasks is to combine epidemiological and genetic data to better understand the role of different hosts and genotypes in the transmission of the parasite. The aim of the present study was to describe the epidemiology of cystic echinococcosis in cattle and sheep, and to characterise the genotypes of E. granulosus present in these farm animals. The study was carried out in the Pampa region of Argentina, with a particular focus on Buenos Aires province, where cystic echinococcosis represents an important human and veterinary health problem. Among 513 cattle and 792 sheep, 11.9% and 4.0%, respectively, were infected with E. granulosus. Genetic characterisation of 42 isolates from cattle and 34 isolates from sheep was carried out by sequencing mitochondrial cox1 and nad1 genes. The vast majority of isolates were identified as genotype G1, except for a single sheep isolate determined as genotype G2, and a single cattle isolate that corresponded to genotype G5. Genotype G1 has previously been found to be the most infectious genotype to humans. As G1 was also the genotype principally responsible for cystic echinococcosis in Buenos Aires province, these results have important implications for developing effective disease control programmes to improve human and animal healthcare in this region.
Fil: Andresiuk, Maria Vanesa. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Gordo, Francisco Ponce. Universidad de Barcelona. Facultad de Farmacia; España
Fil: Saarma, Merilin. University Of Tartu.; Estonia
Fil: Elissondo, María Celina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Taraborelli, Ana. Frigorífico Anselmo. Buenos Aires; Argentina
Fil: Casalongue, Claudia. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Denegri, Guillermo Maria. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Saarma, Urmas. University Of Tartu.; Estonia
Materia
Echinococcosis
Echinococcus Granulosus
Livestock
Epidemiology
Genotypes
Argentina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/25324
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/25324
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in ArgentinaAndresiuk, Maria VanesaGordo, Francisco PonceSaarma, MerilinElissondo, María CelinaTaraborelli, AnaCasalongue, ClaudiaDenegri, Guillermo MariaSaarma, UrmasEchinococcosisEchinococcus GranulosusLivestockEpidemiologyGenotypesArgentinaCystic echinococcosis (hydatidosis) is a severe and widespread disease, caused by the larval stage of the tapeworm Echinococcus granulosus; it affects large numbers of humans and farm animals annually, causing serious health and economic problems. Molecular studies have identified large genetic variation within the E. granulosus complex, with various hosts displaying different susceptibility to different genotypes. For the effective management of the disease, one of the most pressing tasks is to combine epidemiological and genetic data to better understand the role of different hosts and genotypes in the transmission of the parasite. The aim of the present study was to describe the epidemiology of cystic echinococcosis in cattle and sheep, and to characterise the genotypes of E. granulosus present in these farm animals. The study was carried out in the Pampa region of Argentina, with a particular focus on Buenos Aires province, where cystic echinococcosis represents an important human and veterinary health problem. Among 513 cattle and 792 sheep, 11.9% and 4.0%, respectively, were infected with E. granulosus. Genetic characterisation of 42 isolates from cattle and 34 isolates from sheep was carried out by sequencing mitochondrial cox1 and nad1 genes. The vast majority of isolates were identified as genotype G1, except for a single sheep isolate determined as genotype G2, and a single cattle isolate that corresponded to genotype G5. Genotype G1 has previously been found to be the most infectious genotype to humans. As G1 was also the genotype principally responsible for cystic echinococcosis in Buenos Aires province, these results have important implications for developing effective disease control programmes to improve human and animal healthcare in this region.Fil: Andresiuk, Maria Vanesa. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Gordo, Francisco Ponce. Universidad de Barcelona. Facultad de Farmacia; EspañaFil: Saarma, Merilin. University Of Tartu.; EstoniaFil: Elissondo, María Celina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Taraborelli, Ana. Frigorífico Anselmo. Buenos Aires; ArgentinaFil: Casalongue, Claudia. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Denegri, Guillermo Maria. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Saarma, Urmas. University Of Tartu.; EstoniaElsevier Science2013-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/25324Andresiuk, Maria Vanesa; Gordo, Francisco Ponce; Saarma, Merilin; Elissondo, María Celina; Taraborelli, Ana; et al.; Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina; Elsevier Science; Acta Tropica; 127; 4-2013; 136-1420001-706XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.actatropica.2013.04.008info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0001706X1300106Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:43:47Zoai:ri.conicet.gov.ar:11336/25324instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:43:47.493CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
title Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
spellingShingle Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
Andresiuk, Maria Vanesa
Echinococcosis
Echinococcus Granulosus
Livestock
Epidemiology
Genotypes
Argentina
title_short Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
title_full Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
title_fullStr Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
title_full_unstemmed Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
title_sort Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina
dc.creator.none.fl_str_mv Andresiuk, Maria Vanesa
Gordo, Francisco Ponce
Saarma, Merilin
Elissondo, María Celina
Taraborelli, Ana
Casalongue, Claudia
Denegri, Guillermo Maria
Saarma, Urmas
author Andresiuk, Maria Vanesa
author_facet Andresiuk, Maria Vanesa
Gordo, Francisco Ponce
Saarma, Merilin
Elissondo, María Celina
Taraborelli, Ana
Casalongue, Claudia
Denegri, Guillermo Maria
Saarma, Urmas
author_role author
author2 Gordo, Francisco Ponce
Saarma, Merilin
Elissondo, María Celina
Taraborelli, Ana
Casalongue, Claudia
Denegri, Guillermo Maria
Saarma, Urmas
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Echinococcosis
Echinococcus Granulosus
Livestock
Epidemiology
Genotypes
Argentina
topic Echinococcosis
Echinococcus Granulosus
Livestock
Epidemiology
Genotypes
Argentina
dc.description.none.fl_txt_mv Cystic echinococcosis (hydatidosis) is a severe and widespread disease, caused by the larval stage of the tapeworm Echinococcus granulosus; it affects large numbers of humans and farm animals annually, causing serious health and economic problems. Molecular studies have identified large genetic variation within the E. granulosus complex, with various hosts displaying different susceptibility to different genotypes. For the effective management of the disease, one of the most pressing tasks is to combine epidemiological and genetic data to better understand the role of different hosts and genotypes in the transmission of the parasite. The aim of the present study was to describe the epidemiology of cystic echinococcosis in cattle and sheep, and to characterise the genotypes of E. granulosus present in these farm animals. The study was carried out in the Pampa region of Argentina, with a particular focus on Buenos Aires province, where cystic echinococcosis represents an important human and veterinary health problem. Among 513 cattle and 792 sheep, 11.9% and 4.0%, respectively, were infected with E. granulosus. Genetic characterisation of 42 isolates from cattle and 34 isolates from sheep was carried out by sequencing mitochondrial cox1 and nad1 genes. The vast majority of isolates were identified as genotype G1, except for a single sheep isolate determined as genotype G2, and a single cattle isolate that corresponded to genotype G5. Genotype G1 has previously been found to be the most infectious genotype to humans. As G1 was also the genotype principally responsible for cystic echinococcosis in Buenos Aires province, these results have important implications for developing effective disease control programmes to improve human and animal healthcare in this region.
Fil: Andresiuk, Maria Vanesa. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Gordo, Francisco Ponce. Universidad de Barcelona. Facultad de Farmacia; España
Fil: Saarma, Merilin. University Of Tartu.; Estonia
Fil: Elissondo, María Celina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Taraborelli, Ana. Frigorífico Anselmo. Buenos Aires; Argentina
Fil: Casalongue, Claudia. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Denegri, Guillermo Maria. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Saarma, Urmas. University Of Tartu.; Estonia
description Cystic echinococcosis (hydatidosis) is a severe and widespread disease, caused by the larval stage of the tapeworm Echinococcus granulosus; it affects large numbers of humans and farm animals annually, causing serious health and economic problems. Molecular studies have identified large genetic variation within the E. granulosus complex, with various hosts displaying different susceptibility to different genotypes. For the effective management of the disease, one of the most pressing tasks is to combine epidemiological and genetic data to better understand the role of different hosts and genotypes in the transmission of the parasite. The aim of the present study was to describe the epidemiology of cystic echinococcosis in cattle and sheep, and to characterise the genotypes of E. granulosus present in these farm animals. The study was carried out in the Pampa region of Argentina, with a particular focus on Buenos Aires province, where cystic echinococcosis represents an important human and veterinary health problem. Among 513 cattle and 792 sheep, 11.9% and 4.0%, respectively, were infected with E. granulosus. Genetic characterisation of 42 isolates from cattle and 34 isolates from sheep was carried out by sequencing mitochondrial cox1 and nad1 genes. The vast majority of isolates were identified as genotype G1, except for a single sheep isolate determined as genotype G2, and a single cattle isolate that corresponded to genotype G5. Genotype G1 has previously been found to be the most infectious genotype to humans. As G1 was also the genotype principally responsible for cystic echinococcosis in Buenos Aires province, these results have important implications for developing effective disease control programmes to improve human and animal healthcare in this region.
publishDate 2013
dc.date.none.fl_str_mv 2013-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/25324
Andresiuk, Maria Vanesa; Gordo, Francisco Ponce; Saarma, Merilin; Elissondo, María Celina; Taraborelli, Ana; et al.; Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina; Elsevier Science; Acta Tropica; 127; 4-2013; 136-142
0001-706X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/25324
identifier_str_mv Andresiuk, Maria Vanesa; Gordo, Francisco Ponce; Saarma, Merilin; Elissondo, María Celina; Taraborelli, Ana; et al.; Echinococcus granulosus genotype G1 dominated in cattle and sheep during 2003–2006 in Buenos Aires province, an endemic area for cystic echinococcosis in Argentina; Elsevier Science; Acta Tropica; 127; 4-2013; 136-142
0001-706X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.actatropica.2013.04.008
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0001706X1300106X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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