Flow rate resonance of actively deforming particles

Autores
Parisi, Daniel Ricardo; Wiebke, Lucas E.; Mandl, Judith N.; Textor, Johannes
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Lymphoid organs are unusual multicellular tissues: they are densely packed, but the lymphocytes trafficking through them are actively moving. We hypothesize that the intriguing ability of lymphocytes to avoid jamming and clogging is in part attributable to the dynamic shape changesthat cells undergo when they move. In this work, we test this hypothesis by investigating an idealized system, namely, the flow of self-propelled, oscillating particles passing through a narrow constriction in two dimensions (2D), using numerical simulations. We found that deformation allows particles with these properties to flow through a narrow constriction in conditions when non-deformable particles would not be able to do so. Such a flowing state requires the amplitude and frequency of oscillations to exceed threshold values. Moreover, a resonance leading to the maximum flow rate was found when the oscillation frequency matched the natural frequency of the particle related to its elastic stiffness. To our knowledge, this phenomenon has not been described previously. Our findings could have important implications for understanding and controlling flow in a variety of systems in addition to lymphoid organs, such as granular flows subjected to vibration.
Fil: Parisi, Daniel Ricardo. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Wiebke, Lucas E.. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Mandl, Judith N.. McGill University; Canadá
Fil: Textor, Johannes. Radboud Universiteit Nijmegen; Países Bajos
Materia
discret flow
active particles
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/239591
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Flow rate resonance of actively deforming particlesParisi, Daniel RicardoWiebke, Lucas E.Mandl, Judith N.Textor, Johannesdiscret flowactive particleshttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1Lymphoid organs are unusual multicellular tissues: they are densely packed, but the lymphocytes trafficking through them are actively moving. We hypothesize that the intriguing ability of lymphocytes to avoid jamming and clogging is in part attributable to the dynamic shape changesthat cells undergo when they move. In this work, we test this hypothesis by investigating an idealized system, namely, the flow of self-propelled, oscillating particles passing through a narrow constriction in two dimensions (2D), using numerical simulations. We found that deformation allows particles with these properties to flow through a narrow constriction in conditions when non-deformable particles would not be able to do so. Such a flowing state requires the amplitude and frequency of oscillations to exceed threshold values. Moreover, a resonance leading to the maximum flow rate was found when the oscillation frequency matched the natural frequency of the particle related to its elastic stiffness. To our knowledge, this phenomenon has not been described previously. Our findings could have important implications for understanding and controlling flow in a variety of systems in addition to lymphoid organs, such as granular flows subjected to vibration.Fil: Parisi, Daniel Ricardo. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Wiebke, Lucas E.. Instituto Tecnológico de Buenos Aires; ArgentinaFil: Mandl, Judith N.. McGill University; CanadáFil: Textor, Johannes. Radboud Universiteit Nijmegen; Países BajosNature2023-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/239591Parisi, Daniel Ricardo; Wiebke, Lucas E.; Mandl, Judith N.; Textor, Johannes; Flow rate resonance of actively deforming particles; Nature; Scientific Reports; 13; 1; 6-2023; 1-82045-2322CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41598-023-36182-5info:eu-repo/semantics/altIdentifier/doi/10.1038/s41598-023-36182-5info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:56:42Zoai:ri.conicet.gov.ar:11336/239591instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:56:42.658CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Flow rate resonance of actively deforming particles
title Flow rate resonance of actively deforming particles
spellingShingle Flow rate resonance of actively deforming particles
Parisi, Daniel Ricardo
discret flow
active particles
title_short Flow rate resonance of actively deforming particles
title_full Flow rate resonance of actively deforming particles
title_fullStr Flow rate resonance of actively deforming particles
title_full_unstemmed Flow rate resonance of actively deforming particles
title_sort Flow rate resonance of actively deforming particles
dc.creator.none.fl_str_mv Parisi, Daniel Ricardo
Wiebke, Lucas E.
Mandl, Judith N.
Textor, Johannes
author Parisi, Daniel Ricardo
author_facet Parisi, Daniel Ricardo
Wiebke, Lucas E.
Mandl, Judith N.
Textor, Johannes
author_role author
author2 Wiebke, Lucas E.
Mandl, Judith N.
Textor, Johannes
author2_role author
author
author
dc.subject.none.fl_str_mv discret flow
active particles
topic discret flow
active particles
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Lymphoid organs are unusual multicellular tissues: they are densely packed, but the lymphocytes trafficking through them are actively moving. We hypothesize that the intriguing ability of lymphocytes to avoid jamming and clogging is in part attributable to the dynamic shape changesthat cells undergo when they move. In this work, we test this hypothesis by investigating an idealized system, namely, the flow of self-propelled, oscillating particles passing through a narrow constriction in two dimensions (2D), using numerical simulations. We found that deformation allows particles with these properties to flow through a narrow constriction in conditions when non-deformable particles would not be able to do so. Such a flowing state requires the amplitude and frequency of oscillations to exceed threshold values. Moreover, a resonance leading to the maximum flow rate was found when the oscillation frequency matched the natural frequency of the particle related to its elastic stiffness. To our knowledge, this phenomenon has not been described previously. Our findings could have important implications for understanding and controlling flow in a variety of systems in addition to lymphoid organs, such as granular flows subjected to vibration.
Fil: Parisi, Daniel Ricardo. Instituto Tecnológico de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Wiebke, Lucas E.. Instituto Tecnológico de Buenos Aires; Argentina
Fil: Mandl, Judith N.. McGill University; Canadá
Fil: Textor, Johannes. Radboud Universiteit Nijmegen; Países Bajos
description Lymphoid organs are unusual multicellular tissues: they are densely packed, but the lymphocytes trafficking through them are actively moving. We hypothesize that the intriguing ability of lymphocytes to avoid jamming and clogging is in part attributable to the dynamic shape changesthat cells undergo when they move. In this work, we test this hypothesis by investigating an idealized system, namely, the flow of self-propelled, oscillating particles passing through a narrow constriction in two dimensions (2D), using numerical simulations. We found that deformation allows particles with these properties to flow through a narrow constriction in conditions when non-deformable particles would not be able to do so. Such a flowing state requires the amplitude and frequency of oscillations to exceed threshold values. Moreover, a resonance leading to the maximum flow rate was found when the oscillation frequency matched the natural frequency of the particle related to its elastic stiffness. To our knowledge, this phenomenon has not been described previously. Our findings could have important implications for understanding and controlling flow in a variety of systems in addition to lymphoid organs, such as granular flows subjected to vibration.
publishDate 2023
dc.date.none.fl_str_mv 2023-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/239591
Parisi, Daniel Ricardo; Wiebke, Lucas E.; Mandl, Judith N.; Textor, Johannes; Flow rate resonance of actively deforming particles; Nature; Scientific Reports; 13; 1; 6-2023; 1-8
2045-2322
CONICET Digital
CONICET
url http://hdl.handle.net/11336/239591
identifier_str_mv Parisi, Daniel Ricardo; Wiebke, Lucas E.; Mandl, Judith N.; Textor, Johannes; Flow rate resonance of actively deforming particles; Nature; Scientific Reports; 13; 1; 6-2023; 1-8
2045-2322
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41598-023-36182-5
info:eu-repo/semantics/altIdentifier/doi/10.1038/s41598-023-36182-5
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Nature
publisher.none.fl_str_mv Nature
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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