Polyhydroxyalkanoates: Much More than Biodegradable Plastics

Autores
López, Nancy Irene; Pettinari, María Julia; Nikel, Pablo Ivan; Mendez, Beatriz Silvia
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Bacterial polyhydroxyalkanoates (PHAs) are isotactic polymers that play a critical role incentral metabolism, as they act as dynamic reservoirs of carbon and reducing equivalents.These polymers have a number of technical applications since they exhibit thermoplasticand elastomeric properties, making them attractive as a replacement ofoil-derived materials. PHAs are accumulated under conditions of nutritional imbalance(usually an excess of carbon source with respect to a limiting nutrient, such as nitrogenor phosphorus). The cycle of PHA synthesis and degradation has been recognized as animportant physiological feature when these biochemical pathways were originallydescribed, yet its role in bacterial processes as diverse as global regulation and cell survivalis just starting to be appreciated in full. In the present revision, the complex regulationof PHA synthesis and degradation at the transcriptional, translational, andmetabolic levels are explored by analyzing examples in natural producer bacteria,such as Pseudomonas species, as well as in recombinant Escherichia coli strains. Theecological role of PHAs, together with the interrelations with other polymers and extracellularsubstances, is also discussed, along with their importance in cell survival, resistanceto several types of environmental stress, and planktonic-versus-biofilm lifestyle.Finally, bioremediation and plant growth promotion are presented as examples of environmentalapplications in which PHA accumulation has successfully been exploited.
Fil: López, Nancy Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Pettinari, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Nikel, Pablo Ivan. Centro Nacional de Biotecnologia; España
Fil: Mendez, Beatriz Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Materia
Polyhydroxyalkanoates
Biodegradable Plastics
Metabolism
Reducing Equivalents
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/48378
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/48378
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Polyhydroxyalkanoates: Much More than Biodegradable PlasticsLópez, Nancy IrenePettinari, María JuliaNikel, Pablo IvanMendez, Beatriz SilviaPolyhydroxyalkanoatesBiodegradable PlasticsMetabolismReducing Equivalentshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Bacterial polyhydroxyalkanoates (PHAs) are isotactic polymers that play a critical role incentral metabolism, as they act as dynamic reservoirs of carbon and reducing equivalents.These polymers have a number of technical applications since they exhibit thermoplasticand elastomeric properties, making them attractive as a replacement ofoil-derived materials. PHAs are accumulated under conditions of nutritional imbalance(usually an excess of carbon source with respect to a limiting nutrient, such as nitrogenor phosphorus). The cycle of PHA synthesis and degradation has been recognized as animportant physiological feature when these biochemical pathways were originallydescribed, yet its role in bacterial processes as diverse as global regulation and cell survivalis just starting to be appreciated in full. In the present revision, the complex regulationof PHA synthesis and degradation at the transcriptional, translational, andmetabolic levels are explored by analyzing examples in natural producer bacteria,such as Pseudomonas species, as well as in recombinant Escherichia coli strains. Theecological role of PHAs, together with the interrelations with other polymers and extracellularsubstances, is also discussed, along with their importance in cell survival, resistanceto several types of environmental stress, and planktonic-versus-biofilm lifestyle.Finally, bioremediation and plant growth promotion are presented as examples of environmentalapplications in which PHA accumulation has successfully been exploited.Fil: López, Nancy Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Pettinari, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Nikel, Pablo Ivan. Centro Nacional de Biotecnologia; EspañaFil: Mendez, Beatriz Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; ArgentinaElsevier Academic Press Inc2015-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/48378López, Nancy Irene; Pettinari, María Julia; Nikel, Pablo Ivan; Mendez, Beatriz Silvia; Polyhydroxyalkanoates: Much More than Biodegradable Plastics; Elsevier Academic Press Inc; Advances In Applied Microbiology; 93; 10-2015; 73-1060065-2164CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0065216415000313info:eu-repo/semantics/altIdentifier/doi/10.1016/bs.aambs.2015.06.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:15:15Zoai:ri.conicet.gov.ar:11336/48378instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:15:15.409CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Polyhydroxyalkanoates: Much More than Biodegradable Plastics
title Polyhydroxyalkanoates: Much More than Biodegradable Plastics
spellingShingle Polyhydroxyalkanoates: Much More than Biodegradable Plastics
López, Nancy Irene
Polyhydroxyalkanoates
Biodegradable Plastics
Metabolism
Reducing Equivalents
title_short Polyhydroxyalkanoates: Much More than Biodegradable Plastics
title_full Polyhydroxyalkanoates: Much More than Biodegradable Plastics
title_fullStr Polyhydroxyalkanoates: Much More than Biodegradable Plastics
title_full_unstemmed Polyhydroxyalkanoates: Much More than Biodegradable Plastics
title_sort Polyhydroxyalkanoates: Much More than Biodegradable Plastics
dc.creator.none.fl_str_mv López, Nancy Irene
Pettinari, María Julia
Nikel, Pablo Ivan
Mendez, Beatriz Silvia
author López, Nancy Irene
author_facet López, Nancy Irene
Pettinari, María Julia
Nikel, Pablo Ivan
Mendez, Beatriz Silvia
author_role author
author2 Pettinari, María Julia
Nikel, Pablo Ivan
Mendez, Beatriz Silvia
author2_role author
author
author
dc.subject.none.fl_str_mv Polyhydroxyalkanoates
Biodegradable Plastics
Metabolism
Reducing Equivalents
topic Polyhydroxyalkanoates
Biodegradable Plastics
Metabolism
Reducing Equivalents
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Bacterial polyhydroxyalkanoates (PHAs) are isotactic polymers that play a critical role incentral metabolism, as they act as dynamic reservoirs of carbon and reducing equivalents.These polymers have a number of technical applications since they exhibit thermoplasticand elastomeric properties, making them attractive as a replacement ofoil-derived materials. PHAs are accumulated under conditions of nutritional imbalance(usually an excess of carbon source with respect to a limiting nutrient, such as nitrogenor phosphorus). The cycle of PHA synthesis and degradation has been recognized as animportant physiological feature when these biochemical pathways were originallydescribed, yet its role in bacterial processes as diverse as global regulation and cell survivalis just starting to be appreciated in full. In the present revision, the complex regulationof PHA synthesis and degradation at the transcriptional, translational, andmetabolic levels are explored by analyzing examples in natural producer bacteria,such as Pseudomonas species, as well as in recombinant Escherichia coli strains. Theecological role of PHAs, together with the interrelations with other polymers and extracellularsubstances, is also discussed, along with their importance in cell survival, resistanceto several types of environmental stress, and planktonic-versus-biofilm lifestyle.Finally, bioremediation and plant growth promotion are presented as examples of environmentalapplications in which PHA accumulation has successfully been exploited.
Fil: López, Nancy Irene. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Pettinari, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Nikel, Pablo Ivan. Centro Nacional de Biotecnologia; España
Fil: Mendez, Beatriz Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina
description Bacterial polyhydroxyalkanoates (PHAs) are isotactic polymers that play a critical role incentral metabolism, as they act as dynamic reservoirs of carbon and reducing equivalents.These polymers have a number of technical applications since they exhibit thermoplasticand elastomeric properties, making them attractive as a replacement ofoil-derived materials. PHAs are accumulated under conditions of nutritional imbalance(usually an excess of carbon source with respect to a limiting nutrient, such as nitrogenor phosphorus). The cycle of PHA synthesis and degradation has been recognized as animportant physiological feature when these biochemical pathways were originallydescribed, yet its role in bacterial processes as diverse as global regulation and cell survivalis just starting to be appreciated in full. In the present revision, the complex regulationof PHA synthesis and degradation at the transcriptional, translational, andmetabolic levels are explored by analyzing examples in natural producer bacteria,such as Pseudomonas species, as well as in recombinant Escherichia coli strains. Theecological role of PHAs, together with the interrelations with other polymers and extracellularsubstances, is also discussed, along with their importance in cell survival, resistanceto several types of environmental stress, and planktonic-versus-biofilm lifestyle.Finally, bioremediation and plant growth promotion are presented as examples of environmentalapplications in which PHA accumulation has successfully been exploited.
publishDate 2015
dc.date.none.fl_str_mv 2015-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/48378
López, Nancy Irene; Pettinari, María Julia; Nikel, Pablo Ivan; Mendez, Beatriz Silvia; Polyhydroxyalkanoates: Much More than Biodegradable Plastics; Elsevier Academic Press Inc; Advances In Applied Microbiology; 93; 10-2015; 73-106
0065-2164
CONICET Digital
CONICET
url http://hdl.handle.net/11336/48378
identifier_str_mv López, Nancy Irene; Pettinari, María Julia; Nikel, Pablo Ivan; Mendez, Beatriz Silvia; Polyhydroxyalkanoates: Much More than Biodegradable Plastics; Elsevier Academic Press Inc; Advances In Applied Microbiology; 93; 10-2015; 73-106
0065-2164
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0065216415000313
info:eu-repo/semantics/altIdentifier/doi/10.1016/bs.aambs.2015.06.001
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Academic Press Inc
publisher.none.fl_str_mv Elsevier Academic Press Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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