Glycoprotein gene sequence variation in rhesus monkey rhadinovirus

Autores
Shin, Young C.; Jones, Leandro Roberto; Manrique, Julieta Marina; Lauer, William; Carville, Angela; Mansfield, Keith G.; Desrosiers, Ronald C.
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Gene sequences for seven glycoproteins from 20 independent isolates of rhesus monkey rhadinovirus (RRV) and of the corresponding seven glycoprotein genes from nine strains of the Kaposi's sarcoma-associated herpesvirus (KSHV) were obtained and analyzed. Phylogenetic analysis revealed two discrete groupings of RRV gH sequences, two discrete groupings of RRV gL sequences and two discrete groupings of RRV gB sequences. We called these phylogenetic groupings gHa, gHb, gLa, gLb, gBa and gBb. gHa was always paired with gLa and gHb was always paired with gLb for any individual RRV isolate. Since gH and gL are known to be interacting partners, these results suggest the need of matching sequence types for function of these cooperating proteins. gB phylogenetic grouping was not associated with gH/gL phylogenetic grouping. Our results demonstrate two distinct, distantly-related phylogenetic groupings of gH and gL of RRV despite a remarkable degree of sequence conservation within each individual phylogenetic group. © 2010 Elsevier Inc.
Fil: Shin, Young C.. Harvard Medical School; Estados Unidos
Fil: Jones, Leandro Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Playa Unión. Estación de Fotobiología Playa Unión; Argentina
Fil: Manrique, Julieta Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Playa Unión. Estación de Fotobiología Playa Unión; Argentina
Fil: Lauer, William. Harvard Medical School; Estados Unidos
Fil: Carville, Angela. Harvard Medical School; Estados Unidos
Fil: Mansfield, Keith G.. Harvard Medical School; Estados Unidos
Fil: Desrosiers, Ronald C.. Harvard Medical School; Estados Unidos
Materia
Phylogenetic Grouping
Rrv Glycoprotein
Variation
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/62497
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Glycoprotein gene sequence variation in rhesus monkey rhadinovirusShin, Young C.Jones, Leandro RobertoManrique, Julieta MarinaLauer, WilliamCarville, AngelaMansfield, Keith G.Desrosiers, Ronald C.Phylogenetic GroupingRrv GlycoproteinVariationhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Gene sequences for seven glycoproteins from 20 independent isolates of rhesus monkey rhadinovirus (RRV) and of the corresponding seven glycoprotein genes from nine strains of the Kaposi's sarcoma-associated herpesvirus (KSHV) were obtained and analyzed. Phylogenetic analysis revealed two discrete groupings of RRV gH sequences, two discrete groupings of RRV gL sequences and two discrete groupings of RRV gB sequences. We called these phylogenetic groupings gHa, gHb, gLa, gLb, gBa and gBb. gHa was always paired with gLa and gHb was always paired with gLb for any individual RRV isolate. Since gH and gL are known to be interacting partners, these results suggest the need of matching sequence types for function of these cooperating proteins. gB phylogenetic grouping was not associated with gH/gL phylogenetic grouping. Our results demonstrate two distinct, distantly-related phylogenetic groupings of gH and gL of RRV despite a remarkable degree of sequence conservation within each individual phylogenetic group. © 2010 Elsevier Inc.Fil: Shin, Young C.. Harvard Medical School; Estados UnidosFil: Jones, Leandro Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Playa Unión. Estación de Fotobiología Playa Unión; ArgentinaFil: Manrique, Julieta Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Playa Unión. Estación de Fotobiología Playa Unión; ArgentinaFil: Lauer, William. Harvard Medical School; Estados UnidosFil: Carville, Angela. Harvard Medical School; Estados UnidosFil: Mansfield, Keith G.. Harvard Medical School; Estados UnidosFil: Desrosiers, Ronald C.. Harvard Medical School; Estados UnidosAcademic Press Inc Elsevier Science2010-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/62497Shin, Young C.; Jones, Leandro Roberto; Manrique, Julieta Marina; Lauer, William; Carville, Angela; et al.; Glycoprotein gene sequence variation in rhesus monkey rhadinovirus; Academic Press Inc Elsevier Science; Virology; 400; 2; 5-2010; 175-1860042-6822CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.virol.2010.01.030info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0042682210000796info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:26:49Zoai:ri.conicet.gov.ar:11336/62497instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:26:49.36CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
title Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
spellingShingle Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
Shin, Young C.
Phylogenetic Grouping
Rrv Glycoprotein
Variation
title_short Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
title_full Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
title_fullStr Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
title_full_unstemmed Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
title_sort Glycoprotein gene sequence variation in rhesus monkey rhadinovirus
dc.creator.none.fl_str_mv Shin, Young C.
Jones, Leandro Roberto
Manrique, Julieta Marina
Lauer, William
Carville, Angela
Mansfield, Keith G.
Desrosiers, Ronald C.
author Shin, Young C.
author_facet Shin, Young C.
Jones, Leandro Roberto
Manrique, Julieta Marina
Lauer, William
Carville, Angela
Mansfield, Keith G.
Desrosiers, Ronald C.
author_role author
author2 Jones, Leandro Roberto
Manrique, Julieta Marina
Lauer, William
Carville, Angela
Mansfield, Keith G.
Desrosiers, Ronald C.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Phylogenetic Grouping
Rrv Glycoprotein
Variation
topic Phylogenetic Grouping
Rrv Glycoprotein
Variation
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Gene sequences for seven glycoproteins from 20 independent isolates of rhesus monkey rhadinovirus (RRV) and of the corresponding seven glycoprotein genes from nine strains of the Kaposi's sarcoma-associated herpesvirus (KSHV) were obtained and analyzed. Phylogenetic analysis revealed two discrete groupings of RRV gH sequences, two discrete groupings of RRV gL sequences and two discrete groupings of RRV gB sequences. We called these phylogenetic groupings gHa, gHb, gLa, gLb, gBa and gBb. gHa was always paired with gLa and gHb was always paired with gLb for any individual RRV isolate. Since gH and gL are known to be interacting partners, these results suggest the need of matching sequence types for function of these cooperating proteins. gB phylogenetic grouping was not associated with gH/gL phylogenetic grouping. Our results demonstrate two distinct, distantly-related phylogenetic groupings of gH and gL of RRV despite a remarkable degree of sequence conservation within each individual phylogenetic group. © 2010 Elsevier Inc.
Fil: Shin, Young C.. Harvard Medical School; Estados Unidos
Fil: Jones, Leandro Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Playa Unión. Estación de Fotobiología Playa Unión; Argentina
Fil: Manrique, Julieta Marina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Playa Unión. Estación de Fotobiología Playa Unión; Argentina
Fil: Lauer, William. Harvard Medical School; Estados Unidos
Fil: Carville, Angela. Harvard Medical School; Estados Unidos
Fil: Mansfield, Keith G.. Harvard Medical School; Estados Unidos
Fil: Desrosiers, Ronald C.. Harvard Medical School; Estados Unidos
description Gene sequences for seven glycoproteins from 20 independent isolates of rhesus monkey rhadinovirus (RRV) and of the corresponding seven glycoprotein genes from nine strains of the Kaposi's sarcoma-associated herpesvirus (KSHV) were obtained and analyzed. Phylogenetic analysis revealed two discrete groupings of RRV gH sequences, two discrete groupings of RRV gL sequences and two discrete groupings of RRV gB sequences. We called these phylogenetic groupings gHa, gHb, gLa, gLb, gBa and gBb. gHa was always paired with gLa and gHb was always paired with gLb for any individual RRV isolate. Since gH and gL are known to be interacting partners, these results suggest the need of matching sequence types for function of these cooperating proteins. gB phylogenetic grouping was not associated with gH/gL phylogenetic grouping. Our results demonstrate two distinct, distantly-related phylogenetic groupings of gH and gL of RRV despite a remarkable degree of sequence conservation within each individual phylogenetic group. © 2010 Elsevier Inc.
publishDate 2010
dc.date.none.fl_str_mv 2010-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/62497
Shin, Young C.; Jones, Leandro Roberto; Manrique, Julieta Marina; Lauer, William; Carville, Angela; et al.; Glycoprotein gene sequence variation in rhesus monkey rhadinovirus; Academic Press Inc Elsevier Science; Virology; 400; 2; 5-2010; 175-186
0042-6822
CONICET Digital
CONICET
url http://hdl.handle.net/11336/62497
identifier_str_mv Shin, Young C.; Jones, Leandro Roberto; Manrique, Julieta Marina; Lauer, William; Carville, Angela; et al.; Glycoprotein gene sequence variation in rhesus monkey rhadinovirus; Academic Press Inc Elsevier Science; Virology; 400; 2; 5-2010; 175-186
0042-6822
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.virol.2010.01.030
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0042682210000796
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Academic Press Inc Elsevier Science
publisher.none.fl_str_mv Academic Press Inc Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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