Early olfactory experience induces structural changes in the primary olfactory center of an insect brain

Autores
Arenas, Andres; Giurfa, Martín; Sandoz, Jean Christophe; Hourcade, B.; Devaud, J. M.; Farina, Walter Marcelo
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The antennal lobe (AL) is the first olfactory center of the insect brain and is constituted of different functional units, the glomeruli. In the AL, odors are coded as spatiotemporal patterns of glomerular activity. In honeybees, olfactory learning during early adulthood modifies neural activity in the AL on a long-term scale and also enhances later memory retention. By means of behavioral experiments, we first verified that olfactory learning between the fifth and eighth day of adulthood induces better retention performances at a late adult stage than the same experience acquired before or after this period. We checked that the specificity of memory for the odorants used was improved. We then studied whether such early olfactory learning also induces long-term structural changes in the AL consistent with the formation of long-term olfactory memories. We also measured the volume of 15 identified glomeruli in the ALs of 17-day-old honeybees that either experienced an odor associated with sucrose solution between the fifth and eighth day of adulthood or were left untreated. We found that early olfactory experience induces glomerulus-selective increases in volume that were specific to the learned odor. By comparing our volumetric measures with calcium-imaging recordings from a previous study, performed in 17-day-old bees subjected to the same treatment and experimental conditions, we found that glomeruli that showed structural changes after early learning were those that exhibited a significant increase in neural activity. Our results make evident a correlation between structural and functional changes in the AL following early olfactory learning.
Fil: Arenas, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Giurfa, Martín. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Sandoz, Jean Christophe. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Hourcade, B.. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Devaud, J. M.. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Farina, Walter Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Materia
Antennal Lobe
Olfaction
Associative Learning
Early Experiences
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/20313
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/20313
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Early olfactory experience induces structural changes in the primary olfactory center of an insect brainArenas, AndresGiurfa, MartínSandoz, Jean ChristopheHourcade, B.Devaud, J. M.Farina, Walter MarceloAntennal LobeOlfactionAssociative LearningEarly Experienceshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The antennal lobe (AL) is the first olfactory center of the insect brain and is constituted of different functional units, the glomeruli. In the AL, odors are coded as spatiotemporal patterns of glomerular activity. In honeybees, olfactory learning during early adulthood modifies neural activity in the AL on a long-term scale and also enhances later memory retention. By means of behavioral experiments, we first verified that olfactory learning between the fifth and eighth day of adulthood induces better retention performances at a late adult stage than the same experience acquired before or after this period. We checked that the specificity of memory for the odorants used was improved. We then studied whether such early olfactory learning also induces long-term structural changes in the AL consistent with the formation of long-term olfactory memories. We also measured the volume of 15 identified glomeruli in the ALs of 17-day-old honeybees that either experienced an odor associated with sucrose solution between the fifth and eighth day of adulthood or were left untreated. We found that early olfactory experience induces glomerulus-selective increases in volume that were specific to the learned odor. By comparing our volumetric measures with calcium-imaging recordings from a previous study, performed in 17-day-old bees subjected to the same treatment and experimental conditions, we found that glomeruli that showed structural changes after early learning were those that exhibited a significant increase in neural activity. Our results make evident a correlation between structural and functional changes in the AL following early olfactory learning.Fil: Arenas, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Giurfa, Martín. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; FranciaFil: Sandoz, Jean Christophe. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; FranciaFil: Hourcade, B.. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; FranciaFil: Devaud, J. M.. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; FranciaFil: Farina, Walter Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaWiley2012-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/20313Arenas, Andres; Giurfa, Martín; Sandoz, Jean Christophe; Hourcade, B.; Devaud, J. M.; et al.; Early olfactory experience induces structural changes in the primary olfactory center of an insect brain; Wiley; European Journal Of Neuroscience; 35; 5; 2-2012; 682-6900953-816XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1460-9568.2012.07999.xinfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2012.07999.x/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:15:38Zoai:ri.conicet.gov.ar:11336/20313instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:15:38.706CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
title Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
spellingShingle Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
Arenas, Andres
Antennal Lobe
Olfaction
Associative Learning
Early Experiences
title_short Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
title_full Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
title_fullStr Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
title_full_unstemmed Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
title_sort Early olfactory experience induces structural changes in the primary olfactory center of an insect brain
dc.creator.none.fl_str_mv Arenas, Andres
Giurfa, Martín
Sandoz, Jean Christophe
Hourcade, B.
Devaud, J. M.
Farina, Walter Marcelo
author Arenas, Andres
author_facet Arenas, Andres
Giurfa, Martín
Sandoz, Jean Christophe
Hourcade, B.
Devaud, J. M.
Farina, Walter Marcelo
author_role author
author2 Giurfa, Martín
Sandoz, Jean Christophe
Hourcade, B.
Devaud, J. M.
Farina, Walter Marcelo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Antennal Lobe
Olfaction
Associative Learning
Early Experiences
topic Antennal Lobe
Olfaction
Associative Learning
Early Experiences
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The antennal lobe (AL) is the first olfactory center of the insect brain and is constituted of different functional units, the glomeruli. In the AL, odors are coded as spatiotemporal patterns of glomerular activity. In honeybees, olfactory learning during early adulthood modifies neural activity in the AL on a long-term scale and also enhances later memory retention. By means of behavioral experiments, we first verified that olfactory learning between the fifth and eighth day of adulthood induces better retention performances at a late adult stage than the same experience acquired before or after this period. We checked that the specificity of memory for the odorants used was improved. We then studied whether such early olfactory learning also induces long-term structural changes in the AL consistent with the formation of long-term olfactory memories. We also measured the volume of 15 identified glomeruli in the ALs of 17-day-old honeybees that either experienced an odor associated with sucrose solution between the fifth and eighth day of adulthood or were left untreated. We found that early olfactory experience induces glomerulus-selective increases in volume that were specific to the learned odor. By comparing our volumetric measures with calcium-imaging recordings from a previous study, performed in 17-day-old bees subjected to the same treatment and experimental conditions, we found that glomeruli that showed structural changes after early learning were those that exhibited a significant increase in neural activity. Our results make evident a correlation between structural and functional changes in the AL following early olfactory learning.
Fil: Arenas, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Giurfa, Martín. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Sandoz, Jean Christophe. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Hourcade, B.. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Devaud, J. M.. Université de Toulouse; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Farina, Walter Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
description The antennal lobe (AL) is the first olfactory center of the insect brain and is constituted of different functional units, the glomeruli. In the AL, odors are coded as spatiotemporal patterns of glomerular activity. In honeybees, olfactory learning during early adulthood modifies neural activity in the AL on a long-term scale and also enhances later memory retention. By means of behavioral experiments, we first verified that olfactory learning between the fifth and eighth day of adulthood induces better retention performances at a late adult stage than the same experience acquired before or after this period. We checked that the specificity of memory for the odorants used was improved. We then studied whether such early olfactory learning also induces long-term structural changes in the AL consistent with the formation of long-term olfactory memories. We also measured the volume of 15 identified glomeruli in the ALs of 17-day-old honeybees that either experienced an odor associated with sucrose solution between the fifth and eighth day of adulthood or were left untreated. We found that early olfactory experience induces glomerulus-selective increases in volume that were specific to the learned odor. By comparing our volumetric measures with calcium-imaging recordings from a previous study, performed in 17-day-old bees subjected to the same treatment and experimental conditions, we found that glomeruli that showed structural changes after early learning were those that exhibited a significant increase in neural activity. Our results make evident a correlation between structural and functional changes in the AL following early olfactory learning.
publishDate 2012
dc.date.none.fl_str_mv 2012-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/20313
Arenas, Andres; Giurfa, Martín; Sandoz, Jean Christophe; Hourcade, B.; Devaud, J. M.; et al.; Early olfactory experience induces structural changes in the primary olfactory center of an insect brain; Wiley; European Journal Of Neuroscience; 35; 5; 2-2012; 682-690
0953-816X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/20313
identifier_str_mv Arenas, Andres; Giurfa, Martín; Sandoz, Jean Christophe; Hourcade, B.; Devaud, J. M.; et al.; Early olfactory experience induces structural changes in the primary olfactory center of an insect brain; Wiley; European Journal Of Neuroscience; 35; 5; 2-2012; 682-690
0953-816X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1460-9568.2012.07999.x
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1460-9568.2012.07999.x/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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