Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations

Autores
Ang, Li; Vinderola, Celso Gabriel; Endo, Akihito; Kantanen, Juha; Jingfeng, Chen; Binetti, Ana Griselda; Burns, Patricia Graciela; Qingmiao, S.; Suying, Ding; Zujiang, Yu; Rios Covian, David; Mantziari, Anastasia; Beasley, Shea; Gomez Gallego, Carlos; Gueimonde, Miguel; Salminen, Seppo
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Domesticated horses live under different conditions compared with their extinct wild ancestors. While housed, medicated and kept on a restricted source of feed, the microbiota of domesticated horses is hypothesized to be altered. We assessed the fecal microbiome of 57 domestic and feral horses from different locations on three continents, observing geographical differences. A higher abundance of eukaryota (p < 0.05) and viruses (p < 0.05) and lower of archaea (p < 0.05) were found in feral animals when compared with domestic ones. The abundance of genes coding for microbe-produced enzymes involved in the metabolism of carbohydrates was significantly higher (p < 0.05) in feral animals regardless of the geographic origin. Differences in the fecal resistomes between both groups of animals were also noted. The domestic/captive horse microbiomes were enriched in genes conferring resistance to tetracycline, likely reflecting the use of this antibiotic in the management of these animals. Our data showed an impoverishment of the fecal microbiome in domestic horses with diet, antibiotic exposure and hygiene being likely drivers. The results offer a view of the intestinal microbiome of horses and the impact of domestication or captivity, which may uncover novel targets for modulating the microbiome of horses to enhance animal health and well-being.
Fil: Ang, Li. The First Affiliated Hospital of Zhengzhou University; China
Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Endo, Akihito. No especifíca;
Fil: Kantanen, Juha. Production Systems, Natural Resources Institute Finland; Finlandia
Fil: Jingfeng, Chen. Ealth Management Centre, The First Affiliated Hospital; China
Fil: Binetti, Ana Griselda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Burns, Patricia Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Qingmiao, S.. No especifíca;
Fil: Suying, Ding. No especifíca;
Fil: Zujiang, Yu. No especifíca;
Fil: Rios Covian, David. Instituto de Productos Lácteos de Asturias; España
Fil: Mantziari, Anastasia. Functional Foods Forum, Faculty Of Medicine, University; Finlandia
Fil: Beasley, Shea. Functional Foods Forum, Faculty Of Medicine, University; Finlandia
Fil: Gomez Gallego, Carlos. Instituto de Productos Lácteos de Asturias; España
Fil: Gueimonde, Miguel. Instituto de Productos Lácteos de Asturias; España
Fil: Salminen, Seppo. Universidad de Turku; Finlandia
Materia
HORSE
MICROBIOME
DOMESTIC
WILD
FERAL
GLYCOSIDASES
ANTIBIOTIC RESISTANCE GENES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/210490
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/210490
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Gut Microbiome Characteristics in feral and domesticated horses from different geographic locationsAng, LiVinderola, Celso GabrielEndo, AkihitoKantanen, JuhaJingfeng, ChenBinetti, Ana GriseldaBurns, Patricia GracielaQingmiao, S.Suying, DingZujiang, YuRios Covian, DavidMantziari, AnastasiaBeasley, SheaGomez Gallego, CarlosGueimonde, MiguelSalminen, SeppoHORSEMICROBIOMEDOMESTICWILDFERALGLYCOSIDASESANTIBIOTIC RESISTANCE GENEShttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2Domesticated horses live under different conditions compared with their extinct wild ancestors. While housed, medicated and kept on a restricted source of feed, the microbiota of domesticated horses is hypothesized to be altered. We assessed the fecal microbiome of 57 domestic and feral horses from different locations on three continents, observing geographical differences. A higher abundance of eukaryota (p < 0.05) and viruses (p < 0.05) and lower of archaea (p < 0.05) were found in feral animals when compared with domestic ones. The abundance of genes coding for microbe-produced enzymes involved in the metabolism of carbohydrates was significantly higher (p < 0.05) in feral animals regardless of the geographic origin. Differences in the fecal resistomes between both groups of animals were also noted. The domestic/captive horse microbiomes were enriched in genes conferring resistance to tetracycline, likely reflecting the use of this antibiotic in the management of these animals. Our data showed an impoverishment of the fecal microbiome in domestic horses with diet, antibiotic exposure and hygiene being likely drivers. The results offer a view of the intestinal microbiome of horses and the impact of domestication or captivity, which may uncover novel targets for modulating the microbiome of horses to enhance animal health and well-being.Fil: Ang, Li. The First Affiliated Hospital of Zhengzhou University; ChinaFil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; ArgentinaFil: Endo, Akihito. No especifíca;Fil: Kantanen, Juha. Production Systems, Natural Resources Institute Finland; FinlandiaFil: Jingfeng, Chen. Ealth Management Centre, The First Affiliated Hospital; ChinaFil: Binetti, Ana Griselda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; ArgentinaFil: Burns, Patricia Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; ArgentinaFil: Qingmiao, S.. No especifíca;Fil: Suying, Ding. No especifíca;Fil: Zujiang, Yu. No especifíca;Fil: Rios Covian, David. Instituto de Productos Lácteos de Asturias; EspañaFil: Mantziari, Anastasia. Functional Foods Forum, Faculty Of Medicine, University; FinlandiaFil: Beasley, Shea. Functional Foods Forum, Faculty Of Medicine, University; FinlandiaFil: Gomez Gallego, Carlos. Instituto de Productos Lácteos de Asturias; EspañaFil: Gueimonde, Miguel. Instituto de Productos Lácteos de Asturias; EspañaFil: Salminen, Seppo. Universidad de Turku; FinlandiaSpringer2022-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/210490Ang, Li; Vinderola, Celso Gabriel; Endo, Akihito; Kantanen, Juha; Jingfeng, Chen; et al.; Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations; Springer; Communications Biology; 5; 1; 2-2022; 1-102399-3642CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1038/s42003-022-03116-2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:22:07Zoai:ri.conicet.gov.ar:11336/210490instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:22:07.907CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
title Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
spellingShingle Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
Ang, Li
HORSE
MICROBIOME
DOMESTIC
WILD
FERAL
GLYCOSIDASES
ANTIBIOTIC RESISTANCE GENES
title_short Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
title_full Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
title_fullStr Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
title_full_unstemmed Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
title_sort Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations
dc.creator.none.fl_str_mv Ang, Li
Vinderola, Celso Gabriel
Endo, Akihito
Kantanen, Juha
Jingfeng, Chen
Binetti, Ana Griselda
Burns, Patricia Graciela
Qingmiao, S.
Suying, Ding
Zujiang, Yu
Rios Covian, David
Mantziari, Anastasia
Beasley, Shea
Gomez Gallego, Carlos
Gueimonde, Miguel
Salminen, Seppo
author Ang, Li
author_facet Ang, Li
Vinderola, Celso Gabriel
Endo, Akihito
Kantanen, Juha
Jingfeng, Chen
Binetti, Ana Griselda
Burns, Patricia Graciela
Qingmiao, S.
Suying, Ding
Zujiang, Yu
Rios Covian, David
Mantziari, Anastasia
Beasley, Shea
Gomez Gallego, Carlos
Gueimonde, Miguel
Salminen, Seppo
author_role author
author2 Vinderola, Celso Gabriel
Endo, Akihito
Kantanen, Juha
Jingfeng, Chen
Binetti, Ana Griselda
Burns, Patricia Graciela
Qingmiao, S.
Suying, Ding
Zujiang, Yu
Rios Covian, David
Mantziari, Anastasia
Beasley, Shea
Gomez Gallego, Carlos
Gueimonde, Miguel
Salminen, Seppo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv HORSE
MICROBIOME
DOMESTIC
WILD
FERAL
GLYCOSIDASES
ANTIBIOTIC RESISTANCE GENES
topic HORSE
MICROBIOME
DOMESTIC
WILD
FERAL
GLYCOSIDASES
ANTIBIOTIC RESISTANCE GENES
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Domesticated horses live under different conditions compared with their extinct wild ancestors. While housed, medicated and kept on a restricted source of feed, the microbiota of domesticated horses is hypothesized to be altered. We assessed the fecal microbiome of 57 domestic and feral horses from different locations on three continents, observing geographical differences. A higher abundance of eukaryota (p < 0.05) and viruses (p < 0.05) and lower of archaea (p < 0.05) were found in feral animals when compared with domestic ones. The abundance of genes coding for microbe-produced enzymes involved in the metabolism of carbohydrates was significantly higher (p < 0.05) in feral animals regardless of the geographic origin. Differences in the fecal resistomes between both groups of animals were also noted. The domestic/captive horse microbiomes were enriched in genes conferring resistance to tetracycline, likely reflecting the use of this antibiotic in the management of these animals. Our data showed an impoverishment of the fecal microbiome in domestic horses with diet, antibiotic exposure and hygiene being likely drivers. The results offer a view of the intestinal microbiome of horses and the impact of domestication or captivity, which may uncover novel targets for modulating the microbiome of horses to enhance animal health and well-being.
Fil: Ang, Li. The First Affiliated Hospital of Zhengzhou University; China
Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Endo, Akihito. No especifíca;
Fil: Kantanen, Juha. Production Systems, Natural Resources Institute Finland; Finlandia
Fil: Jingfeng, Chen. Ealth Management Centre, The First Affiliated Hospital; China
Fil: Binetti, Ana Griselda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Burns, Patricia Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Fil: Qingmiao, S.. No especifíca;
Fil: Suying, Ding. No especifíca;
Fil: Zujiang, Yu. No especifíca;
Fil: Rios Covian, David. Instituto de Productos Lácteos de Asturias; España
Fil: Mantziari, Anastasia. Functional Foods Forum, Faculty Of Medicine, University; Finlandia
Fil: Beasley, Shea. Functional Foods Forum, Faculty Of Medicine, University; Finlandia
Fil: Gomez Gallego, Carlos. Instituto de Productos Lácteos de Asturias; España
Fil: Gueimonde, Miguel. Instituto de Productos Lácteos de Asturias; España
Fil: Salminen, Seppo. Universidad de Turku; Finlandia
description Domesticated horses live under different conditions compared with their extinct wild ancestors. While housed, medicated and kept on a restricted source of feed, the microbiota of domesticated horses is hypothesized to be altered. We assessed the fecal microbiome of 57 domestic and feral horses from different locations on three continents, observing geographical differences. A higher abundance of eukaryota (p < 0.05) and viruses (p < 0.05) and lower of archaea (p < 0.05) were found in feral animals when compared with domestic ones. The abundance of genes coding for microbe-produced enzymes involved in the metabolism of carbohydrates was significantly higher (p < 0.05) in feral animals regardless of the geographic origin. Differences in the fecal resistomes between both groups of animals were also noted. The domestic/captive horse microbiomes were enriched in genes conferring resistance to tetracycline, likely reflecting the use of this antibiotic in the management of these animals. Our data showed an impoverishment of the fecal microbiome in domestic horses with diet, antibiotic exposure and hygiene being likely drivers. The results offer a view of the intestinal microbiome of horses and the impact of domestication or captivity, which may uncover novel targets for modulating the microbiome of horses to enhance animal health and well-being.
publishDate 2022
dc.date.none.fl_str_mv 2022-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/210490
Ang, Li; Vinderola, Celso Gabriel; Endo, Akihito; Kantanen, Juha; Jingfeng, Chen; et al.; Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations; Springer; Communications Biology; 5; 1; 2-2022; 1-10
2399-3642
CONICET Digital
CONICET
url http://hdl.handle.net/11336/210490
identifier_str_mv Ang, Li; Vinderola, Celso Gabriel; Endo, Akihito; Kantanen, Juha; Jingfeng, Chen; et al.; Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations; Springer; Communications Biology; 5; 1; 2-2022; 1-10
2399-3642
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1038/s42003-022-03116-2
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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