Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles

Autores
Bracamonte, Angel Guillermo; Veglia, Alicia Viviana
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The cyclodextrins effects on the serotonin (5HT) and 5-hydroxy-3-indolyl acetic acid (5HIA) fluorescence emission in acid and alkaline quenching conditions were analyzed. From Stern-Volmer plots, the quenching constants (KQ) were determined in the presence and absence of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD). In both media a decrease in the values of KQ was observed in the presence of CDs, as compared with their absence. In acid media, the decrease was: 36-39% with βCD and 48-54% with HPβCD for 5HIA and 5HT, respectively. In basic media, with the neutral receptors, these values are 69-29% with βCD and 56-43% with HPβCD for 5HIA and 5HT, respectively. Moreover, a complete quenching inhibition produced by ionized cyclodextrins was determined for both substrates. The results showed a net protective effect due to the guest inclusion into the cyclodextrin nanocavity. This study is particularly important for analytical determinations in such media. © 2013 Elsevier B.V. All rights reserved.
Fil: Bracamonte, Angel Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Veglia, Alicia Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia
5-HYDROXY-3-INDOLYL ACETIC ACID
CYCLODEXTRIN NANOCAVITY
FLUORESCENCE QUENCHING
PROTECTIVE INHIBITION
SEROTONIN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/185198
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indolesBracamonte, Angel GuillermoVeglia, Alicia Viviana5-HYDROXY-3-INDOLYL ACETIC ACIDCYCLODEXTRIN NANOCAVITYFLUORESCENCE QUENCHINGPROTECTIVE INHIBITIONSEROTONINhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The cyclodextrins effects on the serotonin (5HT) and 5-hydroxy-3-indolyl acetic acid (5HIA) fluorescence emission in acid and alkaline quenching conditions were analyzed. From Stern-Volmer plots, the quenching constants (KQ) were determined in the presence and absence of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD). In both media a decrease in the values of KQ was observed in the presence of CDs, as compared with their absence. In acid media, the decrease was: 36-39% with βCD and 48-54% with HPβCD for 5HIA and 5HT, respectively. In basic media, with the neutral receptors, these values are 69-29% with βCD and 56-43% with HPβCD for 5HIA and 5HT, respectively. Moreover, a complete quenching inhibition produced by ionized cyclodextrins was determined for both substrates. The results showed a net protective effect due to the guest inclusion into the cyclodextrin nanocavity. This study is particularly important for analytical determinations in such media. © 2013 Elsevier B.V. All rights reserved.Fil: Bracamonte, Angel Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Veglia, Alicia Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaElsevier Science SA2013-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/185198Bracamonte, Angel Guillermo; Veglia, Alicia Viviana; Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles; Elsevier Science SA; Journal of Photochemistry and Photobiology A: Chemistry; 261; 6-2013; 20-251010-60301873-2666CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S101060301300138Xinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jphotochem.2013.04.001info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:39:23Zoai:ri.conicet.gov.ar:11336/185198instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:39:23.684CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
title Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
spellingShingle Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
Bracamonte, Angel Guillermo
5-HYDROXY-3-INDOLYL ACETIC ACID
CYCLODEXTRIN NANOCAVITY
FLUORESCENCE QUENCHING
PROTECTIVE INHIBITION
SEROTONIN
title_short Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
title_full Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
title_fullStr Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
title_full_unstemmed Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
title_sort Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles
dc.creator.none.fl_str_mv Bracamonte, Angel Guillermo
Veglia, Alicia Viviana
author Bracamonte, Angel Guillermo
author_facet Bracamonte, Angel Guillermo
Veglia, Alicia Viviana
author_role author
author2 Veglia, Alicia Viviana
author2_role author
dc.subject.none.fl_str_mv 5-HYDROXY-3-INDOLYL ACETIC ACID
CYCLODEXTRIN NANOCAVITY
FLUORESCENCE QUENCHING
PROTECTIVE INHIBITION
SEROTONIN
topic 5-HYDROXY-3-INDOLYL ACETIC ACID
CYCLODEXTRIN NANOCAVITY
FLUORESCENCE QUENCHING
PROTECTIVE INHIBITION
SEROTONIN
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The cyclodextrins effects on the serotonin (5HT) and 5-hydroxy-3-indolyl acetic acid (5HIA) fluorescence emission in acid and alkaline quenching conditions were analyzed. From Stern-Volmer plots, the quenching constants (KQ) were determined in the presence and absence of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD). In both media a decrease in the values of KQ was observed in the presence of CDs, as compared with their absence. In acid media, the decrease was: 36-39% with βCD and 48-54% with HPβCD for 5HIA and 5HT, respectively. In basic media, with the neutral receptors, these values are 69-29% with βCD and 56-43% with HPβCD for 5HIA and 5HT, respectively. Moreover, a complete quenching inhibition produced by ionized cyclodextrins was determined for both substrates. The results showed a net protective effect due to the guest inclusion into the cyclodextrin nanocavity. This study is particularly important for analytical determinations in such media. © 2013 Elsevier B.V. All rights reserved.
Fil: Bracamonte, Angel Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Veglia, Alicia Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description The cyclodextrins effects on the serotonin (5HT) and 5-hydroxy-3-indolyl acetic acid (5HIA) fluorescence emission in acid and alkaline quenching conditions were analyzed. From Stern-Volmer plots, the quenching constants (KQ) were determined in the presence and absence of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD). In both media a decrease in the values of KQ was observed in the presence of CDs, as compared with their absence. In acid media, the decrease was: 36-39% with βCD and 48-54% with HPβCD for 5HIA and 5HT, respectively. In basic media, with the neutral receptors, these values are 69-29% with βCD and 56-43% with HPβCD for 5HIA and 5HT, respectively. Moreover, a complete quenching inhibition produced by ionized cyclodextrins was determined for both substrates. The results showed a net protective effect due to the guest inclusion into the cyclodextrin nanocavity. This study is particularly important for analytical determinations in such media. © 2013 Elsevier B.V. All rights reserved.
publishDate 2013
dc.date.none.fl_str_mv 2013-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/185198
Bracamonte, Angel Guillermo; Veglia, Alicia Viviana; Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles; Elsevier Science SA; Journal of Photochemistry and Photobiology A: Chemistry; 261; 6-2013; 20-25
1010-6030
1873-2666
CONICET Digital
CONICET
url http://hdl.handle.net/11336/185198
identifier_str_mv Bracamonte, Angel Guillermo; Veglia, Alicia Viviana; Cyclodextrins nanocavities effects on basic and acid fluorescence quenching of hydroxy-indoles; Elsevier Science SA; Journal of Photochemistry and Photobiology A: Chemistry; 261; 6-2013; 20-25
1010-6030
1873-2666
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S101060301300138X
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jphotochem.2013.04.001
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science SA
publisher.none.fl_str_mv Elsevier Science SA
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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