Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples

Autores
Vicario, Ana Laura; Solari, Victor Manuel; Felici, Carlos Emiliano; Aragón, Leslie; Bertolino, Franco Adrián; Gomez, Maria Roxana Anabel
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Molecular imprinted polymer coated Silica (Si-MIP) particles were prepared using non-covalent approach. The Si-MIP material was employed as selective solid phase extraction sorbent for the determination of benzylparaben (BP) in samples of environmental and cosmetic origin. The preconcentration step was studied firstly in a batch system and subsequently it was optimized and adapted to an automatized flow system and the eluate was then analyzed by HPLC-UV. The whole procedure was validated, showing satisfactory analytical parameters. The methodology was applied to real samples showing extraction recoveries always better than 98.85%. A linear response within the concentration range of 1.11 × 10−5–0.025 mg mL−1 was obtained for BP (r2 = 0.9998). The limits of detection and quantification after Si-MIP-HPLC procedure were 3.34 and 11.16 ng mL−1, respectively. The developed methodology provided a simple an economic way for accomplishing a clean-up/preconcentration step and the subsequent determination of BP in a complex matrix. The showed selectivity plus robustness and the possibility of reutilization, enable it to be used for BP routine monitoring in personal care products (PCP) and environmental samples.
Fil: Vicario, Ana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Solari, Victor Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Fil: Felici, Carlos Emiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Fil: Aragón, Leslie. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Farmacia; Argentina
Fil: Bertolino, Franco Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Fil: Gomez, Maria Roxana Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Materia
SI-MIP
HPLC-UV
COSMETICS
PARABENS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/87341
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/87341
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samplesVicario, Ana LauraSolari, Victor ManuelFelici, Carlos EmilianoAragón, LeslieBertolino, Franco AdriánGomez, Maria Roxana AnabelSI-MIPHPLC-UVCOSMETICSPARABENShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Molecular imprinted polymer coated Silica (Si-MIP) particles were prepared using non-covalent approach. The Si-MIP material was employed as selective solid phase extraction sorbent for the determination of benzylparaben (BP) in samples of environmental and cosmetic origin. The preconcentration step was studied firstly in a batch system and subsequently it was optimized and adapted to an automatized flow system and the eluate was then analyzed by HPLC-UV. The whole procedure was validated, showing satisfactory analytical parameters. The methodology was applied to real samples showing extraction recoveries always better than 98.85%. A linear response within the concentration range of 1.11 × 10−5–0.025 mg mL−1 was obtained for BP (r2 = 0.9998). The limits of detection and quantification after Si-MIP-HPLC procedure were 3.34 and 11.16 ng mL−1, respectively. The developed methodology provided a simple an economic way for accomplishing a clean-up/preconcentration step and the subsequent determination of BP in a complex matrix. The showed selectivity plus robustness and the possibility of reutilization, enable it to be used for BP routine monitoring in personal care products (PCP) and environmental samples.Fil: Vicario, Ana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Solari, Victor Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; ArgentinaFil: Felici, Carlos Emiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; ArgentinaFil: Aragón, Leslie. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Farmacia; ArgentinaFil: Bertolino, Franco Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; ArgentinaFil: Gomez, Maria Roxana Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; ArgentinaElsevier Science2018-11-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/87341Vicario, Ana Laura; Solari, Victor Manuel; Felici, Carlos Emiliano; Aragón, Leslie; Bertolino, Franco Adrián; et al.; Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples; Elsevier Science; Microchemical Journal; 142; 19-11-2018; 329-3340026-265XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0026265X18303424info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2018.06.031info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:37:42Zoai:ri.conicet.gov.ar:11336/87341instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:37:43.009CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
title Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
spellingShingle Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
Vicario, Ana Laura
SI-MIP
HPLC-UV
COSMETICS
PARABENS
title_short Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
title_full Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
title_fullStr Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
title_full_unstemmed Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
title_sort Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples
dc.creator.none.fl_str_mv Vicario, Ana Laura
Solari, Victor Manuel
Felici, Carlos Emiliano
Aragón, Leslie
Bertolino, Franco Adrián
Gomez, Maria Roxana Anabel
author Vicario, Ana Laura
author_facet Vicario, Ana Laura
Solari, Victor Manuel
Felici, Carlos Emiliano
Aragón, Leslie
Bertolino, Franco Adrián
Gomez, Maria Roxana Anabel
author_role author
author2 Solari, Victor Manuel
Felici, Carlos Emiliano
Aragón, Leslie
Bertolino, Franco Adrián
Gomez, Maria Roxana Anabel
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv SI-MIP
HPLC-UV
COSMETICS
PARABENS
topic SI-MIP
HPLC-UV
COSMETICS
PARABENS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Molecular imprinted polymer coated Silica (Si-MIP) particles were prepared using non-covalent approach. The Si-MIP material was employed as selective solid phase extraction sorbent for the determination of benzylparaben (BP) in samples of environmental and cosmetic origin. The preconcentration step was studied firstly in a batch system and subsequently it was optimized and adapted to an automatized flow system and the eluate was then analyzed by HPLC-UV. The whole procedure was validated, showing satisfactory analytical parameters. The methodology was applied to real samples showing extraction recoveries always better than 98.85%. A linear response within the concentration range of 1.11 × 10−5–0.025 mg mL−1 was obtained for BP (r2 = 0.9998). The limits of detection and quantification after Si-MIP-HPLC procedure were 3.34 and 11.16 ng mL−1, respectively. The developed methodology provided a simple an economic way for accomplishing a clean-up/preconcentration step and the subsequent determination of BP in a complex matrix. The showed selectivity plus robustness and the possibility of reutilization, enable it to be used for BP routine monitoring in personal care products (PCP) and environmental samples.
Fil: Vicario, Ana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Solari, Victor Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Fil: Felici, Carlos Emiliano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Fil: Aragón, Leslie. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Farmacia; Argentina
Fil: Bertolino, Franco Adrián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
Fil: Gomez, Maria Roxana Anabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina; Argentina
description Molecular imprinted polymer coated Silica (Si-MIP) particles were prepared using non-covalent approach. The Si-MIP material was employed as selective solid phase extraction sorbent for the determination of benzylparaben (BP) in samples of environmental and cosmetic origin. The preconcentration step was studied firstly in a batch system and subsequently it was optimized and adapted to an automatized flow system and the eluate was then analyzed by HPLC-UV. The whole procedure was validated, showing satisfactory analytical parameters. The methodology was applied to real samples showing extraction recoveries always better than 98.85%. A linear response within the concentration range of 1.11 × 10−5–0.025 mg mL−1 was obtained for BP (r2 = 0.9998). The limits of detection and quantification after Si-MIP-HPLC procedure were 3.34 and 11.16 ng mL−1, respectively. The developed methodology provided a simple an economic way for accomplishing a clean-up/preconcentration step and the subsequent determination of BP in a complex matrix. The showed selectivity plus robustness and the possibility of reutilization, enable it to be used for BP routine monitoring in personal care products (PCP) and environmental samples.
publishDate 2018
dc.date.none.fl_str_mv 2018-11-19
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/87341
Vicario, Ana Laura; Solari, Victor Manuel; Felici, Carlos Emiliano; Aragón, Leslie; Bertolino, Franco Adrián; et al.; Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples; Elsevier Science; Microchemical Journal; 142; 19-11-2018; 329-334
0026-265X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/87341
identifier_str_mv Vicario, Ana Laura; Solari, Victor Manuel; Felici, Carlos Emiliano; Aragón, Leslie; Bertolino, Franco Adrián; et al.; Molecular imprinting on surface of silica particles for the selective extraction of benzylparaben in flow system applied to cosmetics and water samples; Elsevier Science; Microchemical Journal; 142; 19-11-2018; 329-334
0026-265X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0026265X18303424
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2018.06.031
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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