A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas
- Autores
- Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007.
Fil: Saeed, Aamer. Quaid-I-Azam University; Pakistán
Fil: Florke, Ulrich. Universität Paderborn; Alemania
Fil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina - Materia
-
Biological Activity
Metal Complexation
Molecular Structure
Sulfur Chemistry
Thiourea
Vibrational Properties - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
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- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/24974
Ver los metadatos del registro completo
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A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureasSaeed, AamerFlorke, UlrichErben, Mauricio FedericoBiological ActivityMetal ComplexationMolecular StructureSulfur ChemistryThioureaVibrational Propertieshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007.Fil: Saeed, Aamer. Quaid-I-Azam University; PakistánFil: Florke, Ulrich. Universität Paderborn; AlemaniaFil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaTaylor & Francis Ltd2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24974Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico; A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas; Taylor & Francis Ltd; Journal Of Sulfur Chemistry; 35; 3; 4-2014; 318-3551741-5993CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1080/17415993.2013.834904info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.1080/17415993.2013.834904info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:15:21Zoai:ri.conicet.gov.ar:11336/24974instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:15:21.835CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| title |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| spellingShingle |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas Saeed, Aamer Biological Activity Metal Complexation Molecular Structure Sulfur Chemistry Thiourea Vibrational Properties |
| title_short |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| title_full |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| title_fullStr |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| title_full_unstemmed |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| title_sort |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
| dc.creator.none.fl_str_mv |
Saeed, Aamer Florke, Ulrich Erben, Mauricio Federico |
| author |
Saeed, Aamer |
| author_facet |
Saeed, Aamer Florke, Ulrich Erben, Mauricio Federico |
| author_role |
author |
| author2 |
Florke, Ulrich Erben, Mauricio Federico |
| author2_role |
author author |
| dc.subject.none.fl_str_mv |
Biological Activity Metal Complexation Molecular Structure Sulfur Chemistry Thiourea Vibrational Properties |
| topic |
Biological Activity Metal Complexation Molecular Structure Sulfur Chemistry Thiourea Vibrational Properties |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| dc.description.none.fl_txt_mv |
This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007. Fil: Saeed, Aamer. Quaid-I-Azam University; Pakistán Fil: Florke, Ulrich. Universität Paderborn; Alemania Fil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina |
| description |
This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-04 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
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publishedVersion |
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http://hdl.handle.net/11336/24974 Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico; A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas; Taylor & Francis Ltd; Journal Of Sulfur Chemistry; 35; 3; 4-2014; 318-355 1741-5993 CONICET Digital CONICET |
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http://hdl.handle.net/11336/24974 |
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Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico; A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas; Taylor & Francis Ltd; Journal Of Sulfur Chemistry; 35; 3; 4-2014; 318-355 1741-5993 CONICET Digital CONICET |
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eng |
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eng |
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Taylor & Francis Ltd |
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Taylor & Francis Ltd |
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