A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas
- Autores
- Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007.
Fil: Saeed, Aamer. Quaid-I-Azam University; Pakistán
Fil: Florke, Ulrich. Universität Paderborn; Alemania
Fil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina - Materia
-
Biological Activity
Metal Complexation
Molecular Structure
Sulfur Chemistry
Thiourea
Vibrational Properties - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/24974
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A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureasSaeed, AamerFlorke, UlrichErben, Mauricio FedericoBiological ActivityMetal ComplexationMolecular StructureSulfur ChemistryThioureaVibrational Propertieshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007.Fil: Saeed, Aamer. Quaid-I-Azam University; PakistánFil: Florke, Ulrich. Universität Paderborn; AlemaniaFil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaTaylor & Francis Ltd2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24974Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico; A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas; Taylor & Francis Ltd; Journal Of Sulfur Chemistry; 35; 3; 4-2014; 318-3551741-5993CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1080/17415993.2013.834904info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.1080/17415993.2013.834904info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:31Zoai:ri.conicet.gov.ar:11336/24974instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:31.753CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
title |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
spellingShingle |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas Saeed, Aamer Biological Activity Metal Complexation Molecular Structure Sulfur Chemistry Thiourea Vibrational Properties |
title_short |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
title_full |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
title_fullStr |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
title_full_unstemmed |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
title_sort |
A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas |
dc.creator.none.fl_str_mv |
Saeed, Aamer Florke, Ulrich Erben, Mauricio Federico |
author |
Saeed, Aamer |
author_facet |
Saeed, Aamer Florke, Ulrich Erben, Mauricio Federico |
author_role |
author |
author2 |
Florke, Ulrich Erben, Mauricio Federico |
author2_role |
author author |
dc.subject.none.fl_str_mv |
Biological Activity Metal Complexation Molecular Structure Sulfur Chemistry Thiourea Vibrational Properties |
topic |
Biological Activity Metal Complexation Molecular Structure Sulfur Chemistry Thiourea Vibrational Properties |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007. Fil: Saeed, Aamer. Quaid-I-Azam University; Pakistán Fil: Florke, Ulrich. Universität Paderborn; Alemania Fil: Erben, Mauricio Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina |
description |
This review provides an overview of the chemistry, structure and potential applications of 1- (acyl/aroyl)-3-(mono-substituted) and 1-(acyl/aroyl)-3,3-(di-substituted) thioureas, with general formula R1C(O)N(1)HC(S)N(3)R2R3. In recent years, the title compounds have found extensive applications as ligands in coordination chemistry. The effect that nitrogen substituents exert on the intra- and intermolecular hydrogen-bonding interactions is discussed, including their role on the coordination properties displayed by these ligands. Novel applications of transition metal complexes bearing 1-(acyl/aroyl)-3-(mono- and di-substituted) thioureas are introduced. Biological aspects are also highlighted. As recently demonstrated, high-throughput screening assay and structure–activity analyses are feasible for this class of compounds. The chemical versatility of 1-(acyl)-3-(substituted) thiourea molecules and the derived metal complexes, together with the possibility of determining detailed structural properties, join biological applications in a promising interdisciplinary approach. The bibliography includes 382 references with emphasis on the literature appearing after 2007. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-04 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/24974 Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico; A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas; Taylor & Francis Ltd; Journal Of Sulfur Chemistry; 35; 3; 4-2014; 318-355 1741-5993 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/24974 |
identifier_str_mv |
Saeed, Aamer; Florke, Ulrich; Erben, Mauricio Federico; A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3- (substituted) thioureas; Taylor & Francis Ltd; Journal Of Sulfur Chemistry; 35; 3; 4-2014; 318-355 1741-5993 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1080/17415993.2013.834904 info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.1080/17415993.2013.834904 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Taylor & Francis Ltd |
publisher.none.fl_str_mv |
Taylor & Francis Ltd |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844613452843188224 |
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13.070432 |