Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay

Autores
Pasteran, Fernando; Martinez Mora, Mario; Albornoz, Ezequiel Pablo; Faccone, Diego Francisco; Franco, Rossana; Ortellado, Juana; Melgarejo, Nancy; Gómez, Sonia Alejandra; Riquelme, Irma; Matheu, Jorge; Ramon Pardo, Jorge Matheu Pilar; Corso, Alejandra
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The New Delhi metallo-β-lactamase (NDM-1) was initially identified in Escherichia coli and Klebsiella pneumoniae isolates in Sweden, from a patient previously hospitalized in India.1 To date, NDM producers in Latin America have been scarce, and associated with species of Enterobacteriaceae from Guatemala, Mexico, Colombia and Brazil, although in Honduras it was reported in Acinetobacter baumannii.2?6 Here, we report two genetically unrelated NDM-1-producing Acinetobacter pittii isolates identified in Paraguay. Since 1996, the Pan American Health Organization (PAHO) has supported a regional surveillance system, the Antimicrobial Resistance Surveillance Network in Latin America (ReLAVRA), that includes 794 laboratories from 20 Latin American countries, including their respective reference laboratories.7 This network provides reliable, timely and reproducible microbiological data in order to improve patient care. A regional protocol for the detection of carbapenemases has been harmonized and implemented through ReLAVRA. Briefly, metallo-β-lactamase (MBL) production is suspected in isolates that exhibit decreased susceptibility to carbapenems (CLSI criteria) and a positive synergy test result between a disc containing 10 μg of imipenem and a disc containing 750 μg of EDTA plus 1900 μg of sodium thioglycolate.8 During 2012, following the ReLAVRA algorithm, the National Health Laboratory of Paraguay confirmed an MBL phenotype in two Acinetobacter spp. isolates recovered from a single hospital. This phenotype had not previously been observed in Acinetobacter spp. from Paraguay.
Fil: Pasteran, Fernando. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina
Fil: Martinez Mora, Mario. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; Paraguay
Fil: Albornoz, Ezequiel Pablo. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Faccone, Diego Francisco. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Franco, Rossana. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; Paraguay
Fil: Ortellado, Juana. Universidad Nacional de Asunción; Paraguay
Fil: Melgarejo, Nancy. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; Paraguay
Fil: Gómez, Sonia Alejandra. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Riquelme, Irma. Universidad Nacional de Asunción; Paraguay
Fil: Matheu, Jorge. Pan American Health Organization. Antimicrobial Resistance and Infection Control Program; Estados Unidos
Fil: Ramon Pardo, Jorge Matheu Pilar. Pan American Health Organization. Antimicrobial Resistance and Infection Control Program; Estados Unidos
Fil: Corso, Alejandra. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Carbapenemases
Resistance
Ndm-1
Paediatric
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/33759
Acceder
id CONICETDig_952466b0cf58f0a1f8b9d79a37923c43
oai_identifier_str oai:ri.conicet.gov.ar:11336/33759
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in ParaguayPasteran, FernandoMartinez Mora, MarioAlbornoz, Ezequiel PabloFaccone, Diego FranciscoFranco, RossanaOrtellado, JuanaMelgarejo, NancyGómez, Sonia AlejandraRiquelme, IrmaMatheu, JorgeRamon Pardo, Jorge Matheu PilarCorso, AlejandraCarbapenemasesResistanceNdm-1Paediatrichttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1The New Delhi metallo-β-lactamase (NDM-1) was initially identified in Escherichia coli and Klebsiella pneumoniae isolates in Sweden, from a patient previously hospitalized in India.1 To date, NDM producers in Latin America have been scarce, and associated with species of Enterobacteriaceae from Guatemala, Mexico, Colombia and Brazil, although in Honduras it was reported in Acinetobacter baumannii.2?6 Here, we report two genetically unrelated NDM-1-producing Acinetobacter pittii isolates identified in Paraguay. Since 1996, the Pan American Health Organization (PAHO) has supported a regional surveillance system, the Antimicrobial Resistance Surveillance Network in Latin America (ReLAVRA), that includes 794 laboratories from 20 Latin American countries, including their respective reference laboratories.7 This network provides reliable, timely and reproducible microbiological data in order to improve patient care. A regional protocol for the detection of carbapenemases has been harmonized and implemented through ReLAVRA. Briefly, metallo-β-lactamase (MBL) production is suspected in isolates that exhibit decreased susceptibility to carbapenems (CLSI criteria) and a positive synergy test result between a disc containing 10 μg of imipenem and a disc containing 750 μg of EDTA plus 1900 μg of sodium thioglycolate.8 During 2012, following the ReLAVRA algorithm, the National Health Laboratory of Paraguay confirmed an MBL phenotype in two Acinetobacter spp. isolates recovered from a single hospital. This phenotype had not previously been observed in Acinetobacter spp. from Paraguay.Fil: Pasteran, Fernando. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; ArgentinaFil: Martinez Mora, Mario. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; ParaguayFil: Albornoz, Ezequiel Pablo. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Faccone, Diego Francisco. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Franco, Rossana. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; ParaguayFil: Ortellado, Juana. Universidad Nacional de Asunción; ParaguayFil: Melgarejo, Nancy. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; ParaguayFil: Gómez, Sonia Alejandra. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Riquelme, Irma. Universidad Nacional de Asunción; ParaguayFil: Matheu, Jorge. Pan American Health Organization. Antimicrobial Resistance and Infection Control Program; Estados UnidosFil: Ramon Pardo, Jorge Matheu Pilar. Pan American Health Organization. Antimicrobial Resistance and Infection Control Program; Estados UnidosFil: Corso, Alejandra. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaOxford University Press2014-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/33759Pasteran, Fernando; Martinez Mora, Mario; Albornoz, Ezequiel Pablo; Faccone, Diego Francisco; Franco, Rossana; et al.; Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay; Oxford University Press; Journal of Antimicrobial Chemotherapy; 69; 9; 5-2014; 2575-25780305-74531460-2091CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/jac/article/69/9/2575/707050info:eu-repo/semantics/altIdentifier/doi/10.1093/jac/dku139info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:25Zoai:ri.conicet.gov.ar:11336/33759instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:26.183CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
title Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
spellingShingle Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
Pasteran, Fernando
Carbapenemases
Resistance
Ndm-1
Paediatric
title_short Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
title_full Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
title_fullStr Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
title_full_unstemmed Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
title_sort Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay
dc.creator.none.fl_str_mv Pasteran, Fernando
Martinez Mora, Mario
Albornoz, Ezequiel Pablo
Faccone, Diego Francisco
Franco, Rossana
Ortellado, Juana
Melgarejo, Nancy
Gómez, Sonia Alejandra
Riquelme, Irma
Matheu, Jorge
Ramon Pardo, Jorge Matheu Pilar
Corso, Alejandra
author Pasteran, Fernando
author_facet Pasteran, Fernando
Martinez Mora, Mario
Albornoz, Ezequiel Pablo
Faccone, Diego Francisco
Franco, Rossana
Ortellado, Juana
Melgarejo, Nancy
Gómez, Sonia Alejandra
Riquelme, Irma
Matheu, Jorge
Ramon Pardo, Jorge Matheu Pilar
Corso, Alejandra
author_role author
author2 Martinez Mora, Mario
Albornoz, Ezequiel Pablo
Faccone, Diego Francisco
Franco, Rossana
Ortellado, Juana
Melgarejo, Nancy
Gómez, Sonia Alejandra
Riquelme, Irma
Matheu, Jorge
Ramon Pardo, Jorge Matheu Pilar
Corso, Alejandra
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Carbapenemases
Resistance
Ndm-1
Paediatric
topic Carbapenemases
Resistance
Ndm-1
Paediatric
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The New Delhi metallo-β-lactamase (NDM-1) was initially identified in Escherichia coli and Klebsiella pneumoniae isolates in Sweden, from a patient previously hospitalized in India.1 To date, NDM producers in Latin America have been scarce, and associated with species of Enterobacteriaceae from Guatemala, Mexico, Colombia and Brazil, although in Honduras it was reported in Acinetobacter baumannii.2?6 Here, we report two genetically unrelated NDM-1-producing Acinetobacter pittii isolates identified in Paraguay. Since 1996, the Pan American Health Organization (PAHO) has supported a regional surveillance system, the Antimicrobial Resistance Surveillance Network in Latin America (ReLAVRA), that includes 794 laboratories from 20 Latin American countries, including their respective reference laboratories.7 This network provides reliable, timely and reproducible microbiological data in order to improve patient care. A regional protocol for the detection of carbapenemases has been harmonized and implemented through ReLAVRA. Briefly, metallo-β-lactamase (MBL) production is suspected in isolates that exhibit decreased susceptibility to carbapenems (CLSI criteria) and a positive synergy test result between a disc containing 10 μg of imipenem and a disc containing 750 μg of EDTA plus 1900 μg of sodium thioglycolate.8 During 2012, following the ReLAVRA algorithm, the National Health Laboratory of Paraguay confirmed an MBL phenotype in two Acinetobacter spp. isolates recovered from a single hospital. This phenotype had not previously been observed in Acinetobacter spp. from Paraguay.
Fil: Pasteran, Fernando. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina
Fil: Martinez Mora, Mario. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; Paraguay
Fil: Albornoz, Ezequiel Pablo. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Faccone, Diego Francisco. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Franco, Rossana. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; Paraguay
Fil: Ortellado, Juana. Universidad Nacional de Asunción; Paraguay
Fil: Melgarejo, Nancy. Laboratorio Central de Salud Pública. Servicio Antimicrobianos; Paraguay
Fil: Gómez, Sonia Alejandra. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Riquelme, Irma. Universidad Nacional de Asunción; Paraguay
Fil: Matheu, Jorge. Pan American Health Organization. Antimicrobial Resistance and Infection Control Program; Estados Unidos
Fil: Ramon Pardo, Jorge Matheu Pilar. Pan American Health Organization. Antimicrobial Resistance and Infection Control Program; Estados Unidos
Fil: Corso, Alejandra. Dirección Nacional de Institutos de Investigación. Administración Nacional de Laboratorios e Institutos de Salud. Instituto Nacional de Enfermedades Infecciosas. Área de Antimicrobianos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description The New Delhi metallo-β-lactamase (NDM-1) was initially identified in Escherichia coli and Klebsiella pneumoniae isolates in Sweden, from a patient previously hospitalized in India.1 To date, NDM producers in Latin America have been scarce, and associated with species of Enterobacteriaceae from Guatemala, Mexico, Colombia and Brazil, although in Honduras it was reported in Acinetobacter baumannii.2?6 Here, we report two genetically unrelated NDM-1-producing Acinetobacter pittii isolates identified in Paraguay. Since 1996, the Pan American Health Organization (PAHO) has supported a regional surveillance system, the Antimicrobial Resistance Surveillance Network in Latin America (ReLAVRA), that includes 794 laboratories from 20 Latin American countries, including their respective reference laboratories.7 This network provides reliable, timely and reproducible microbiological data in order to improve patient care. A regional protocol for the detection of carbapenemases has been harmonized and implemented through ReLAVRA. Briefly, metallo-β-lactamase (MBL) production is suspected in isolates that exhibit decreased susceptibility to carbapenems (CLSI criteria) and a positive synergy test result between a disc containing 10 μg of imipenem and a disc containing 750 μg of EDTA plus 1900 μg of sodium thioglycolate.8 During 2012, following the ReLAVRA algorithm, the National Health Laboratory of Paraguay confirmed an MBL phenotype in two Acinetobacter spp. isolates recovered from a single hospital. This phenotype had not previously been observed in Acinetobacter spp. from Paraguay.
publishDate 2014
dc.date.none.fl_str_mv 2014-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/33759
Pasteran, Fernando; Martinez Mora, Mario; Albornoz, Ezequiel Pablo; Faccone, Diego Francisco; Franco, Rossana; et al.; Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay; Oxford University Press; Journal of Antimicrobial Chemotherapy; 69; 9; 5-2014; 2575-2578
0305-7453
1460-2091
CONICET Digital
CONICET
url http://hdl.handle.net/11336/33759
identifier_str_mv Pasteran, Fernando; Martinez Mora, Mario; Albornoz, Ezequiel Pablo; Faccone, Diego Francisco; Franco, Rossana; et al.; Emergence of genetically unrelated NDM-1-producing Acinetobacter pittii strains in Paraguay; Oxford University Press; Journal of Antimicrobial Chemotherapy; 69; 9; 5-2014; 2575-2578
0305-7453
1460-2091
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/jac/article/69/9/2575/707050
info:eu-repo/semantics/altIdentifier/doi/10.1093/jac/dku139
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613450163027968
score 13.070432

Publicaciones similares