A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)

Autores
Avila, Héctor Gabriel; Cejas, Rosa Graciela; Cabrera, Marta Graciela; Sawicki, Mirna; Santillan, Graciela Ines; Periago, Maria Victoria
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Cystic echinococcosis (CE) is endemic in Argentina, and approximately 30% of the national territory has characteristics appropriate for the development of the zoonotic domestic cycle of this disease. This community-wide study was implemented in rural areas of Añatuya, Santiago del Estero (northern Argentina) to determine the presence of Echinococcus granulosus sensu lato in the definitive host (dogs) and the presence of CE in humans. Infection data from dogs were obtained through the collection and analysis of fecal samples; these were processed through sedimentation/flotation techniques and PCR. The presence in humans was determined by ultrasound (US) and serology (ELISA confirmed by Western Blot—WB) in the Miel de Palo settlement. A standardized questionnaire was used to investigate potential risk factors for CE; more than half of the studied population carried out activities that favor the maintenance of the cycle. The prevalence of E. granulosus s.l. in dogs from 10 rural settlements, confirmed by PCR, was 4.7% (32/678). The results of the US and serology screening showed a human prevalence of 0.55% (1/183) in Miel de Palo. This prevalence increased to 4.9% (9/183) if imaging-negative but serology-positive (ELISA+WB) individuals are included, as per national guidelines. One of the participants with CE, confirmed by US, was less than 15 years old, which evidences the presence of active transmission. A comprehensive multidisciplinary approach, taking into consideration social, behavioral, sanitary, and environmental aspects intimately tied to the parasite cycle, is needed.
Fil: Avila, Héctor Gabriel. Gobierno de la Provincia de San Juan. Ministerio de Salud Publica. Direccion de Epidemiologia. Laboratorio Provincial de Zoonosis.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina
Fil: Cejas, Rosa Graciela. Fundación Mundo Sano; Argentina
Fil: Cabrera, Marta Graciela. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbran". Departamento de Parasitología; Argentina
Fil: Sawicki, Mirna. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Santillan, Graciela Ines. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbran". Departamento de Parasitología; Argentina
Fil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; Argentina
Materia
ARGENTINA
CYSTIC ECHINOCOCCOSIS
SANTIAGO DEL ESTERO
SURVEILLANCE AND CONTROL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/220576
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/220576
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)Avila, Héctor GabrielCejas, Rosa GracielaCabrera, Marta GracielaSawicki, MirnaSantillan, Graciela InesPeriago, Maria VictoriaARGENTINACYSTIC ECHINOCOCCOSISSANTIAGO DEL ESTEROSURVEILLANCE AND CONTROLhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Cystic echinococcosis (CE) is endemic in Argentina, and approximately 30% of the national territory has characteristics appropriate for the development of the zoonotic domestic cycle of this disease. This community-wide study was implemented in rural areas of Añatuya, Santiago del Estero (northern Argentina) to determine the presence of Echinococcus granulosus sensu lato in the definitive host (dogs) and the presence of CE in humans. Infection data from dogs were obtained through the collection and analysis of fecal samples; these were processed through sedimentation/flotation techniques and PCR. The presence in humans was determined by ultrasound (US) and serology (ELISA confirmed by Western Blot—WB) in the Miel de Palo settlement. A standardized questionnaire was used to investigate potential risk factors for CE; more than half of the studied population carried out activities that favor the maintenance of the cycle. The prevalence of E. granulosus s.l. in dogs from 10 rural settlements, confirmed by PCR, was 4.7% (32/678). The results of the US and serology screening showed a human prevalence of 0.55% (1/183) in Miel de Palo. This prevalence increased to 4.9% (9/183) if imaging-negative but serology-positive (ELISA+WB) individuals are included, as per national guidelines. One of the participants with CE, confirmed by US, was less than 15 years old, which evidences the presence of active transmission. A comprehensive multidisciplinary approach, taking into consideration social, behavioral, sanitary, and environmental aspects intimately tied to the parasite cycle, is needed.Fil: Avila, Héctor Gabriel. Gobierno de la Provincia de San Juan. Ministerio de Salud Publica. Direccion de Epidemiologia. Laboratorio Provincial de Zoonosis.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Cejas, Rosa Graciela. Fundación Mundo Sano; ArgentinaFil: Cabrera, Marta Graciela. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbran". Departamento de Parasitología; ArgentinaFil: Sawicki, Mirna. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; ArgentinaFil: Santillan, Graciela Ines. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbran". Departamento de Parasitología; ArgentinaFil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; ArgentinaMDPI2022-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/220576Avila, Héctor Gabriel; Cejas, Rosa Graciela; Cabrera, Marta Graciela; Sawicki, Mirna; Santillan, Graciela Ines; et al.; A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina); MDPI; Parasitologia; 2; 4; 11-2022; 326-3372673-6772CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2673-6772/2/4/27info:eu-repo/semantics/altIdentifier/doi/10.3390/parasitologia2040027info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:13:34Zoai:ri.conicet.gov.ar:11336/220576instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:13:35.267CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
title A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
spellingShingle A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
Avila, Héctor Gabriel
ARGENTINA
CYSTIC ECHINOCOCCOSIS
SANTIAGO DEL ESTERO
SURVEILLANCE AND CONTROL
title_short A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
title_full A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
title_fullStr A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
title_full_unstemmed A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
title_sort A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina)
dc.creator.none.fl_str_mv Avila, Héctor Gabriel
Cejas, Rosa Graciela
Cabrera, Marta Graciela
Sawicki, Mirna
Santillan, Graciela Ines
Periago, Maria Victoria
author Avila, Héctor Gabriel
author_facet Avila, Héctor Gabriel
Cejas, Rosa Graciela
Cabrera, Marta Graciela
Sawicki, Mirna
Santillan, Graciela Ines
Periago, Maria Victoria
author_role author
author2 Cejas, Rosa Graciela
Cabrera, Marta Graciela
Sawicki, Mirna
Santillan, Graciela Ines
Periago, Maria Victoria
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ARGENTINA
CYSTIC ECHINOCOCCOSIS
SANTIAGO DEL ESTERO
SURVEILLANCE AND CONTROL
topic ARGENTINA
CYSTIC ECHINOCOCCOSIS
SANTIAGO DEL ESTERO
SURVEILLANCE AND CONTROL
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Cystic echinococcosis (CE) is endemic in Argentina, and approximately 30% of the national territory has characteristics appropriate for the development of the zoonotic domestic cycle of this disease. This community-wide study was implemented in rural areas of Añatuya, Santiago del Estero (northern Argentina) to determine the presence of Echinococcus granulosus sensu lato in the definitive host (dogs) and the presence of CE in humans. Infection data from dogs were obtained through the collection and analysis of fecal samples; these were processed through sedimentation/flotation techniques and PCR. The presence in humans was determined by ultrasound (US) and serology (ELISA confirmed by Western Blot—WB) in the Miel de Palo settlement. A standardized questionnaire was used to investigate potential risk factors for CE; more than half of the studied population carried out activities that favor the maintenance of the cycle. The prevalence of E. granulosus s.l. in dogs from 10 rural settlements, confirmed by PCR, was 4.7% (32/678). The results of the US and serology screening showed a human prevalence of 0.55% (1/183) in Miel de Palo. This prevalence increased to 4.9% (9/183) if imaging-negative but serology-positive (ELISA+WB) individuals are included, as per national guidelines. One of the participants with CE, confirmed by US, was less than 15 years old, which evidences the presence of active transmission. A comprehensive multidisciplinary approach, taking into consideration social, behavioral, sanitary, and environmental aspects intimately tied to the parasite cycle, is needed.
Fil: Avila, Héctor Gabriel. Gobierno de la Provincia de San Juan. Ministerio de Salud Publica. Direccion de Epidemiologia. Laboratorio Provincial de Zoonosis.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina
Fil: Cejas, Rosa Graciela. Fundación Mundo Sano; Argentina
Fil: Cabrera, Marta Graciela. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbran". Departamento de Parasitología; Argentina
Fil: Sawicki, Mirna. Gobierno de la Ciudad de Buenos Aires. Hospital de Infecciosas "Dr. Francisco Javier Muñiz"; Argentina
Fil: Santillan, Graciela Ines. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud "Dr. C. G. Malbran". Departamento de Parasitología; Argentina
Fil: Periago, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fundación Mundo Sano; Argentina
description Cystic echinococcosis (CE) is endemic in Argentina, and approximately 30% of the national territory has characteristics appropriate for the development of the zoonotic domestic cycle of this disease. This community-wide study was implemented in rural areas of Añatuya, Santiago del Estero (northern Argentina) to determine the presence of Echinococcus granulosus sensu lato in the definitive host (dogs) and the presence of CE in humans. Infection data from dogs were obtained through the collection and analysis of fecal samples; these were processed through sedimentation/flotation techniques and PCR. The presence in humans was determined by ultrasound (US) and serology (ELISA confirmed by Western Blot—WB) in the Miel de Palo settlement. A standardized questionnaire was used to investigate potential risk factors for CE; more than half of the studied population carried out activities that favor the maintenance of the cycle. The prevalence of E. granulosus s.l. in dogs from 10 rural settlements, confirmed by PCR, was 4.7% (32/678). The results of the US and serology screening showed a human prevalence of 0.55% (1/183) in Miel de Palo. This prevalence increased to 4.9% (9/183) if imaging-negative but serology-positive (ELISA+WB) individuals are included, as per national guidelines. One of the participants with CE, confirmed by US, was less than 15 years old, which evidences the presence of active transmission. A comprehensive multidisciplinary approach, taking into consideration social, behavioral, sanitary, and environmental aspects intimately tied to the parasite cycle, is needed.
publishDate 2022
dc.date.none.fl_str_mv 2022-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/220576
Avila, Héctor Gabriel; Cejas, Rosa Graciela; Cabrera, Marta Graciela; Sawicki, Mirna; Santillan, Graciela Ines; et al.; A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina); MDPI; Parasitologia; 2; 4; 11-2022; 326-337
2673-6772
CONICET Digital
CONICET
url http://hdl.handle.net/11336/220576
identifier_str_mv Avila, Héctor Gabriel; Cejas, Rosa Graciela; Cabrera, Marta Graciela; Sawicki, Mirna; Santillan, Graciela Ines; et al.; A Cross-Sectional Study to Detect Cystic Echinococcosis in Añatuya, Santiago Del Estero (Argentina); MDPI; Parasitologia; 2; 4; 11-2022; 326-337
2673-6772
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2673-6772/2/4/27
info:eu-repo/semantics/altIdentifier/doi/10.3390/parasitologia2040027
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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