Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex

Autores
Miranda, Magdalena; Bekinschtein, Pedro Alejandro
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In this review we explore the role of the perirhinal cortex (Prh) in memory, focusing on the cellular and molecular mechanisms that have been described to happen in this structure. The Prh is part of the medial temporal lobe, but the evidences show that it has a different function than that of the hippocampus. In particular, the Prh is known to be important for object recognition memory, although it could have a role in other types of memory. However, despite the fact that object recognition tasks are widely used, information regarding the molecular and cellular mechanisms underlying this type of memory in Prh is lacking. We discuss a series of studies of memory and plasticity in this region and how they might relate. In addition, we propose that Prh could play a role as a “pattern separator” for object memories, similar to the function of the dentate gyrus of the hippocampus in the spatial domain.
Fil: Miranda, Magdalena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
Fil: Bekinschtein, Pedro Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
Materia
MEMORY
PERIRHINAL CORTEX
PLASTICITY
NEUROBIOLOGY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/93093
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortexMiranda, MagdalenaBekinschtein, Pedro AlejandroMEMORYPERIRHINAL CORTEXPLASTICITYNEUROBIOLOGYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1In this review we explore the role of the perirhinal cortex (Prh) in memory, focusing on the cellular and molecular mechanisms that have been described to happen in this structure. The Prh is part of the medial temporal lobe, but the evidences show that it has a different function than that of the hippocampus. In particular, the Prh is known to be important for object recognition memory, although it could have a role in other types of memory. However, despite the fact that object recognition tasks are widely used, information regarding the molecular and cellular mechanisms underlying this type of memory in Prh is lacking. We discuss a series of studies of memory and plasticity in this region and how they might relate. In addition, we propose that Prh could play a role as a “pattern separator” for object memories, similar to the function of the dentate gyrus of the hippocampus in the spatial domain.Fil: Miranda, Magdalena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Bekinschtein, Pedro Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaPergamon-Elsevier Science Ltd2018-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/93093Miranda, Magdalena; Bekinschtein, Pedro Alejandro; Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex; Pergamon-Elsevier Science Ltd; Neuroscience; 370; 1-2-2018; 46-610306-4522CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuroscience.2017.06.002info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0306452217303986info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:48:02Zoai:ri.conicet.gov.ar:11336/93093instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:48:02.976CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
title Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
spellingShingle Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
Miranda, Magdalena
MEMORY
PERIRHINAL CORTEX
PLASTICITY
NEUROBIOLOGY
title_short Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
title_full Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
title_fullStr Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
title_full_unstemmed Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
title_sort Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex
dc.creator.none.fl_str_mv Miranda, Magdalena
Bekinschtein, Pedro Alejandro
author Miranda, Magdalena
author_facet Miranda, Magdalena
Bekinschtein, Pedro Alejandro
author_role author
author2 Bekinschtein, Pedro Alejandro
author2_role author
dc.subject.none.fl_str_mv MEMORY
PERIRHINAL CORTEX
PLASTICITY
NEUROBIOLOGY
topic MEMORY
PERIRHINAL CORTEX
PLASTICITY
NEUROBIOLOGY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In this review we explore the role of the perirhinal cortex (Prh) in memory, focusing on the cellular and molecular mechanisms that have been described to happen in this structure. The Prh is part of the medial temporal lobe, but the evidences show that it has a different function than that of the hippocampus. In particular, the Prh is known to be important for object recognition memory, although it could have a role in other types of memory. However, despite the fact that object recognition tasks are widely used, information regarding the molecular and cellular mechanisms underlying this type of memory in Prh is lacking. We discuss a series of studies of memory and plasticity in this region and how they might relate. In addition, we propose that Prh could play a role as a “pattern separator” for object memories, similar to the function of the dentate gyrus of the hippocampus in the spatial domain.
Fil: Miranda, Magdalena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
Fil: Bekinschtein, Pedro Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina
description In this review we explore the role of the perirhinal cortex (Prh) in memory, focusing on the cellular and molecular mechanisms that have been described to happen in this structure. The Prh is part of the medial temporal lobe, but the evidences show that it has a different function than that of the hippocampus. In particular, the Prh is known to be important for object recognition memory, although it could have a role in other types of memory. However, despite the fact that object recognition tasks are widely used, information regarding the molecular and cellular mechanisms underlying this type of memory in Prh is lacking. We discuss a series of studies of memory and plasticity in this region and how they might relate. In addition, we propose that Prh could play a role as a “pattern separator” for object memories, similar to the function of the dentate gyrus of the hippocampus in the spatial domain.
publishDate 2018
dc.date.none.fl_str_mv 2018-02-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/93093
Miranda, Magdalena; Bekinschtein, Pedro Alejandro; Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex; Pergamon-Elsevier Science Ltd; Neuroscience; 370; 1-2-2018; 46-61
0306-4522
CONICET Digital
CONICET
url http://hdl.handle.net/11336/93093
identifier_str_mv Miranda, Magdalena; Bekinschtein, Pedro Alejandro; Plasticity mechanisms of memory consolidation and reconsolidation in the perirhinal cortex; Pergamon-Elsevier Science Ltd; Neuroscience; 370; 1-2-2018; 46-61
0306-4522
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.neuroscience.2017.06.002
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0306452217303986
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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