Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders

Autores
Sülsen, Valeria Patricia
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Nature is an important source for the discovery of new bioactive compounds. Natural compounds constitute a strategic starting point for the development of novel drugs, since they exhibit a wide range of pharmacophores and a large number of chiral centers that allow the interaction with proteins and biological targets.Terpenes are natural isoprene-derived compounds and are classified according to the number of carbon atoms in monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), triterpenes (C30), tetraterpenes (C40) and polyterpenes (C > 40). Many of these compounds are considered secondary metabolites in plants. They showed a variety of biological activities, such as anticancer, anti-inflammatory, antimicrobial, antiparasitic, antiviral, etc. They constitute the largest group of natural compounds with more than 50,000 molecules of diverse chemical structures. They are of great interest, both in the cosmetic and the food market as well as in the pharmaceutical industry.Among terpenoids, sesquiterpene lactones and diterpenes stand out due to their role in human health and as a source of new drugs.
Fil: Sülsen, Valeria Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Materia
SESQUITERPENE LACTONES
DITERPENES
PROMISING COMPOUNDS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/173382
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disordersSülsen, Valeria PatriciaSESQUITERPENE LACTONESDITERPENESPROMISING COMPOUNDShttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Nature is an important source for the discovery of new bioactive compounds. Natural compounds constitute a strategic starting point for the development of novel drugs, since they exhibit a wide range of pharmacophores and a large number of chiral centers that allow the interaction with proteins and biological targets.Terpenes are natural isoprene-derived compounds and are classified according to the number of carbon atoms in monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), triterpenes (C30), tetraterpenes (C40) and polyterpenes (C > 40). Many of these compounds are considered secondary metabolites in plants. They showed a variety of biological activities, such as anticancer, anti-inflammatory, antimicrobial, antiparasitic, antiviral, etc. They constitute the largest group of natural compounds with more than 50,000 molecules of diverse chemical structures. They are of great interest, both in the cosmetic and the food market as well as in the pharmaceutical industry.Among terpenoids, sesquiterpene lactones and diterpenes stand out due to their role in human health and as a source of new drugs.Fil: Sülsen, Valeria Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaMolecular Diversity Preservation International2021-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/173382Sülsen, Valeria Patricia; Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders; Molecular Diversity Preservation International; Molecules; 26; 5; 2-2021; 1-41420-3049CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/26/5/1251info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules26051251info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:41:44Zoai:ri.conicet.gov.ar:11336/173382instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:41:45.177CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
title Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
spellingShingle Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
Sülsen, Valeria Patricia
SESQUITERPENE LACTONES
DITERPENES
PROMISING COMPOUNDS
title_short Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
title_full Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
title_fullStr Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
title_full_unstemmed Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
title_sort Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders
dc.creator.none.fl_str_mv Sülsen, Valeria Patricia
author Sülsen, Valeria Patricia
author_facet Sülsen, Valeria Patricia
author_role author
dc.subject.none.fl_str_mv SESQUITERPENE LACTONES
DITERPENES
PROMISING COMPOUNDS
topic SESQUITERPENE LACTONES
DITERPENES
PROMISING COMPOUNDS
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Nature is an important source for the discovery of new bioactive compounds. Natural compounds constitute a strategic starting point for the development of novel drugs, since they exhibit a wide range of pharmacophores and a large number of chiral centers that allow the interaction with proteins and biological targets.Terpenes are natural isoprene-derived compounds and are classified according to the number of carbon atoms in monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), triterpenes (C30), tetraterpenes (C40) and polyterpenes (C > 40). Many of these compounds are considered secondary metabolites in plants. They showed a variety of biological activities, such as anticancer, anti-inflammatory, antimicrobial, antiparasitic, antiviral, etc. They constitute the largest group of natural compounds with more than 50,000 molecules of diverse chemical structures. They are of great interest, both in the cosmetic and the food market as well as in the pharmaceutical industry.Among terpenoids, sesquiterpene lactones and diterpenes stand out due to their role in human health and as a source of new drugs.
Fil: Sülsen, Valeria Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
description Nature is an important source for the discovery of new bioactive compounds. Natural compounds constitute a strategic starting point for the development of novel drugs, since they exhibit a wide range of pharmacophores and a large number of chiral centers that allow the interaction with proteins and biological targets.Terpenes are natural isoprene-derived compounds and are classified according to the number of carbon atoms in monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), triterpenes (C30), tetraterpenes (C40) and polyterpenes (C > 40). Many of these compounds are considered secondary metabolites in plants. They showed a variety of biological activities, such as anticancer, anti-inflammatory, antimicrobial, antiparasitic, antiviral, etc. They constitute the largest group of natural compounds with more than 50,000 molecules of diverse chemical structures. They are of great interest, both in the cosmetic and the food market as well as in the pharmaceutical industry.Among terpenoids, sesquiterpene lactones and diterpenes stand out due to their role in human health and as a source of new drugs.
publishDate 2021
dc.date.none.fl_str_mv 2021-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/173382
Sülsen, Valeria Patricia; Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders; Molecular Diversity Preservation International; Molecules; 26; 5; 2-2021; 1-4
1420-3049
CONICET Digital
CONICET
url http://hdl.handle.net/11336/173382
identifier_str_mv Sülsen, Valeria Patricia; Sesquiterpene lactones and diterpenes: Promising therapeutic candidates for infectious diseases, neoplasms and other chronic disorders; Molecular Diversity Preservation International; Molecules; 26; 5; 2-2021; 1-4
1420-3049
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/26/5/1251
info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules26051251
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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