Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel

Autores
Colinas, Pedro Alfonso; Nunez, Nicolas Antonio; Bravo, Rodolfo Daniel
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The sulfonamidoglycosylation of methyl glycosides in the presence of perchloric acid immobilized on silica gel proceeded effectively to afford the corresponding sulfonamido glycosides with good to high yields with minimal workup and short reaction times. This methodology was applied to the synthesis of some N-glycosyl sulfamides, which showed low nanomolar activity against human carbonic anhydrase.
Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Nunez, Nicolas Antonio. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina
Fil: Bravo, Rodolfo Daniel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina
Materia
METHYL GLYCOSIDES
PERCHLORIC ACID-SILICA
SULFONAMIDOGLYCOSYLATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/148707
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica GelColinas, Pedro AlfonsoNunez, Nicolas AntonioBravo, Rodolfo DanielMETHYL GLYCOSIDESPERCHLORIC ACID-SILICASULFONAMIDOGLYCOSYLATIONhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The sulfonamidoglycosylation of methyl glycosides in the presence of perchloric acid immobilized on silica gel proceeded effectively to afford the corresponding sulfonamido glycosides with good to high yields with minimal workup and short reaction times. This methodology was applied to the synthesis of some N-glycosyl sulfamides, which showed low nanomolar activity against human carbonic anhydrase.Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Nunez, Nicolas Antonio. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; ArgentinaFil: Bravo, Rodolfo Daniel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; ArgentinaTaylor & Francis2008-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/148707Colinas, Pedro Alfonso; Nunez, Nicolas Antonio; Bravo, Rodolfo Daniel; Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel; Taylor & Francis; Journal of Carbohydrate Chemistry; 27; 3; 6-2008; 141-1470732-83031532-2327CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/07328300802030829info:eu-repo/semantics/altIdentifier/doi/10.1080/07328300802030829info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:51:05Zoai:ri.conicet.gov.ar:11336/148707instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:51:05.836CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
title Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
spellingShingle Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
Colinas, Pedro Alfonso
METHYL GLYCOSIDES
PERCHLORIC ACID-SILICA
SULFONAMIDOGLYCOSYLATION
title_short Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
title_full Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
title_fullStr Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
title_full_unstemmed Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
title_sort Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel
dc.creator.none.fl_str_mv Colinas, Pedro Alfonso
Nunez, Nicolas Antonio
Bravo, Rodolfo Daniel
author Colinas, Pedro Alfonso
author_facet Colinas, Pedro Alfonso
Nunez, Nicolas Antonio
Bravo, Rodolfo Daniel
author_role author
author2 Nunez, Nicolas Antonio
Bravo, Rodolfo Daniel
author2_role author
author
dc.subject.none.fl_str_mv METHYL GLYCOSIDES
PERCHLORIC ACID-SILICA
SULFONAMIDOGLYCOSYLATION
topic METHYL GLYCOSIDES
PERCHLORIC ACID-SILICA
SULFONAMIDOGLYCOSYLATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The sulfonamidoglycosylation of methyl glycosides in the presence of perchloric acid immobilized on silica gel proceeded effectively to afford the corresponding sulfonamido glycosides with good to high yields with minimal workup and short reaction times. This methodology was applied to the synthesis of some N-glycosyl sulfamides, which showed low nanomolar activity against human carbonic anhydrase.
Fil: Colinas, Pedro Alfonso. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina
Fil: Nunez, Nicolas Antonio. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina
Fil: Bravo, Rodolfo Daniel. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química. Laboratorio de Estudio de Compuestos Orgánicos; Argentina
description The sulfonamidoglycosylation of methyl glycosides in the presence of perchloric acid immobilized on silica gel proceeded effectively to afford the corresponding sulfonamido glycosides with good to high yields with minimal workup and short reaction times. This methodology was applied to the synthesis of some N-glycosyl sulfamides, which showed low nanomolar activity against human carbonic anhydrase.
publishDate 2008
dc.date.none.fl_str_mv 2008-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/148707
Colinas, Pedro Alfonso; Nunez, Nicolas Antonio; Bravo, Rodolfo Daniel; Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel; Taylor & Francis; Journal of Carbohydrate Chemistry; 27; 3; 6-2008; 141-147
0732-8303
1532-2327
CONICET Digital
CONICET
url http://hdl.handle.net/11336/148707
identifier_str_mv Colinas, Pedro Alfonso; Nunez, Nicolas Antonio; Bravo, Rodolfo Daniel; Sulfonamidoglycosylation of Methyl Glycosides Employing Perchloric Acid Supported on Silica Gel; Taylor & Francis; Journal of Carbohydrate Chemistry; 27; 3; 6-2008; 141-147
0732-8303
1532-2327
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/07328300802030829
info:eu-repo/semantics/altIdentifier/doi/10.1080/07328300802030829
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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