Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors

Autores
Kolliker Frers, Rodolfo Alberto; Otero-losada, Matilde Estela; Kersberg, E.; Cosentino, Vanesa; Capani, Francisco
Año de publicación
2017
Idioma
inglés
Tipo de recurso
parte de libro
Estado
versión publicada
Descripción
cular diseases though the reasons are not clear. Here we discuss the role of the immune system in atherosclerosis and of the proinflammatory status in psoriasis and psoriatic arthritis diseases. Methods. We performed a Pubmed query covering publications within the last ten years including epidemiological studies, cross-sectional case-control studies, and reviews. Articles were selected according critical associations using arthritis, immune-mediated inflammatory diseases, and psoriasis as key fields. These were crossed and combined with atherogenesis, endothelial dysfunction, intima-media thickness, subclinical atherosclerosis, plaque, thrombosis, thrombus, fibrinolysis, coagulation, and reactive oxygen species, all closely related to cardiovascular diseases. Both types of disease selected terms were separately combined with cardiovascular risk factors both non-traditional (innate and adaptive pro- and anti-inflammatory immune molecules and cells), and traditional (metabolic conditions and related molecules). Results and conclusions. Immune-activated crossroads came out as the main contributors to proatherogenic inflammation in psoriasis and psoriatic arthritis disease. Traditional and non-traditional cardiovascular risk factors´ interactions result from an active cross-talk between proatherogenic mediators derived from metabolic, vascular and autoimmune joint and skin inflammation in target tissues. Consistently, psoriasis and psoriatic arthritis diseases offer an invaluable scenario to deepen our knowledge on atherosclerotic cardiovascular disease.
Fil: Kolliker Frers, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Otero-losada, Matilde Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Kersberg, E.. No especifíca;
Fil: Cosentino, Vanesa. No especifíca;
Fil: Capani, Francisco. Universidad Abierta Interamericana. Secretaría de Investigación. Centro de Altos Estudios En Ciencias Humanas y de la Salud - Sede Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Cardiovascular Risk Factors
Inflammation
Psoriatic arthritis
Psoriasis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/138459
Acceder
id CONICETDig_8e2038688612fc9644114d59b62fa983
oai_identifier_str oai:ri.conicet.gov.ar:11336/138459
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk FactorsKolliker Frers, Rodolfo AlbertoOtero-losada, Matilde EstelaKersberg, E.Cosentino, VanesaCapani, FranciscoCardiovascular Risk FactorsInflammationPsoriatic arthritisPsoriasishttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3cular diseases though the reasons are not clear. Here we discuss the role of the immune system in atherosclerosis and of the proinflammatory status in psoriasis and psoriatic arthritis diseases. Methods. We performed a Pubmed query covering publications within the last ten years including epidemiological studies, cross-sectional case-control studies, and reviews. Articles were selected according critical associations using arthritis, immune-mediated inflammatory diseases, and psoriasis as key fields. These were crossed and combined with atherogenesis, endothelial dysfunction, intima-media thickness, subclinical atherosclerosis, plaque, thrombosis, thrombus, fibrinolysis, coagulation, and reactive oxygen species, all closely related to cardiovascular diseases. Both types of disease selected terms were separately combined with cardiovascular risk factors both non-traditional (innate and adaptive pro- and anti-inflammatory immune molecules and cells), and traditional (metabolic conditions and related molecules). Results and conclusions. Immune-activated crossroads came out as the main contributors to proatherogenic inflammation in psoriasis and psoriatic arthritis disease. Traditional and non-traditional cardiovascular risk factors´ interactions result from an active cross-talk between proatherogenic mediators derived from metabolic, vascular and autoimmune joint and skin inflammation in target tissues. Consistently, psoriasis and psoriatic arthritis diseases offer an invaluable scenario to deepen our knowledge on atherosclerotic cardiovascular disease.Fil: Kolliker Frers, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Otero-losada, Matilde Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Kersberg, E.. No especifíca;Fil: Cosentino, Vanesa. No especifíca;Fil: Capani, Francisco. Universidad Abierta Interamericana. Secretaría de Investigación. Centro de Altos Estudios En Ciencias Humanas y de la Salud - Sede Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaIntechOpenChiriac, Anca2017info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookParthttp://purl.org/coar/resource_type/c_3248info:ar-repo/semantics/parteDeLibroapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/138459Kolliker Frers, Rodolfo Alberto; Otero-losada, Matilde Estela; Kersberg, E.; Cosentino, Vanesa; Capani, Francisco; Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors; IntechOpen; 2017; 91-119978-953-51-3252-3CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.intechopen.com/chapters/55538info:eu-repo/semantics/altIdentifier/doi/10.5772/intechopen.68559info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:55:07Zoai:ri.conicet.gov.ar:11336/138459instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:55:07.698CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
title Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
spellingShingle Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
Kolliker Frers, Rodolfo Alberto
Cardiovascular Risk Factors
Inflammation
Psoriatic arthritis
Psoriasis
title_short Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
title_full Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
title_fullStr Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
title_full_unstemmed Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
title_sort Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors
dc.creator.none.fl_str_mv Kolliker Frers, Rodolfo Alberto
Otero-losada, Matilde Estela
Kersberg, E.
Cosentino, Vanesa
Capani, Francisco
author Kolliker Frers, Rodolfo Alberto
author_facet Kolliker Frers, Rodolfo Alberto
Otero-losada, Matilde Estela
Kersberg, E.
Cosentino, Vanesa
Capani, Francisco
author_role author
author2 Otero-losada, Matilde Estela
Kersberg, E.
Cosentino, Vanesa
Capani, Francisco
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Chiriac, Anca
dc.subject.none.fl_str_mv Cardiovascular Risk Factors
Inflammation
Psoriatic arthritis
Psoriasis
topic Cardiovascular Risk Factors
Inflammation
Psoriatic arthritis
Psoriasis
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv cular diseases though the reasons are not clear. Here we discuss the role of the immune system in atherosclerosis and of the proinflammatory status in psoriasis and psoriatic arthritis diseases. Methods. We performed a Pubmed query covering publications within the last ten years including epidemiological studies, cross-sectional case-control studies, and reviews. Articles were selected according critical associations using arthritis, immune-mediated inflammatory diseases, and psoriasis as key fields. These were crossed and combined with atherogenesis, endothelial dysfunction, intima-media thickness, subclinical atherosclerosis, plaque, thrombosis, thrombus, fibrinolysis, coagulation, and reactive oxygen species, all closely related to cardiovascular diseases. Both types of disease selected terms were separately combined with cardiovascular risk factors both non-traditional (innate and adaptive pro- and anti-inflammatory immune molecules and cells), and traditional (metabolic conditions and related molecules). Results and conclusions. Immune-activated crossroads came out as the main contributors to proatherogenic inflammation in psoriasis and psoriatic arthritis disease. Traditional and non-traditional cardiovascular risk factors´ interactions result from an active cross-talk between proatherogenic mediators derived from metabolic, vascular and autoimmune joint and skin inflammation in target tissues. Consistently, psoriasis and psoriatic arthritis diseases offer an invaluable scenario to deepen our knowledge on atherosclerotic cardiovascular disease.
Fil: Kolliker Frers, Rodolfo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Otero-losada, Matilde Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina
Fil: Kersberg, E.. No especifíca;
Fil: Cosentino, Vanesa. No especifíca;
Fil: Capani, Francisco. Universidad Abierta Interamericana. Secretaría de Investigación. Centro de Altos Estudios En Ciencias Humanas y de la Salud - Sede Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description cular diseases though the reasons are not clear. Here we discuss the role of the immune system in atherosclerosis and of the proinflammatory status in psoriasis and psoriatic arthritis diseases. Methods. We performed a Pubmed query covering publications within the last ten years including epidemiological studies, cross-sectional case-control studies, and reviews. Articles were selected according critical associations using arthritis, immune-mediated inflammatory diseases, and psoriasis as key fields. These were crossed and combined with atherogenesis, endothelial dysfunction, intima-media thickness, subclinical atherosclerosis, plaque, thrombosis, thrombus, fibrinolysis, coagulation, and reactive oxygen species, all closely related to cardiovascular diseases. Both types of disease selected terms were separately combined with cardiovascular risk factors both non-traditional (innate and adaptive pro- and anti-inflammatory immune molecules and cells), and traditional (metabolic conditions and related molecules). Results and conclusions. Immune-activated crossroads came out as the main contributors to proatherogenic inflammation in psoriasis and psoriatic arthritis disease. Traditional and non-traditional cardiovascular risk factors´ interactions result from an active cross-talk between proatherogenic mediators derived from metabolic, vascular and autoimmune joint and skin inflammation in target tissues. Consistently, psoriasis and psoriatic arthritis diseases offer an invaluable scenario to deepen our knowledge on atherosclerotic cardiovascular disease.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/bookPart
http://purl.org/coar/resource_type/c_3248
info:ar-repo/semantics/parteDeLibro
status_str publishedVersion
format bookPart
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/138459
Kolliker Frers, Rodolfo Alberto; Otero-losada, Matilde Estela; Kersberg, E.; Cosentino, Vanesa; Capani, Francisco; Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors; IntechOpen; 2017; 91-119
978-953-51-3252-3
CONICET Digital
CONICET
url http://hdl.handle.net/11336/138459
identifier_str_mv Kolliker Frers, Rodolfo Alberto; Otero-losada, Matilde Estela; Kersberg, E.; Cosentino, Vanesa; Capani, Francisco; Immune System Links Psoriasis-Mediated Inflammation to Cardiovascular Diseases via Traditional and Non-Traditional Cardiovascular Risk Factors; IntechOpen; 2017; 91-119
978-953-51-3252-3
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.intechopen.com/chapters/55538
info:eu-repo/semantics/altIdentifier/doi/10.5772/intechopen.68559
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv IntechOpen
publisher.none.fl_str_mv IntechOpen
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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