Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors

Autores
Gomez, Federico Jose Vicente; Martin, Aida; Silva, María Fernanda; Escarpa, Alberto
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the current work, single-wall carbon nanotube press-transferred electrodes (SW-PTEs) were used for detection of melatonin (MT) and its precursors tryptophan (Trp) and serotonin (5-HT) on microchip electrophoresis (ME). SW-PTEs were simply fabricated by press transferring a filtered dispersion of single-wall carbon nanotubes on a nonconductive PMMA substrate, where single-wall carbon nanotubes act as exclusive transducers. The coupling of ME–SW-PTEs allowed the fast detection of MT, Trp, and 5-HT in less than 150 s with excellent analytical features. It exhibited an impressive antifouling performance with RSD values of ≤2 and ≤4% for migration times and peak heights, respectively (n = 12). In addition, sample analysis was also investigated by analysis of 5-HT, MT, and Trp in commercial samples obtaining excellent quantitative and reproducible recoveries with values of 96.2 ± 1.8%, 101.3 ± 0.2%, and 95.6 ± 1.2% for 5-HT, MT, and Trp, respectively. The current novel application reveals the analytical power of the press-transfer technology where the fast and reliable determination of MT and its precursors were performed directly on the nanoscale carbon nanotube detectors without the help of any other electrochemical transducer.
Fil: Gomez, Federico Jose Vicente. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; Argentina
Fil: Martin, Aida. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España
Fil: Silva, María Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; Argentina
Fil: Escarpa, Alberto. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España
Materia
Carbon Nanotubes
Melatonin
Press-Transferred Electrodes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/22875
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursorsGomez, Federico Jose VicenteMartin, AidaSilva, María FernandaEscarpa, AlbertoCarbon NanotubesMelatoninPress-Transferred Electrodeshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In the current work, single-wall carbon nanotube press-transferred electrodes (SW-PTEs) were used for detection of melatonin (MT) and its precursors tryptophan (Trp) and serotonin (5-HT) on microchip electrophoresis (ME). SW-PTEs were simply fabricated by press transferring a filtered dispersion of single-wall carbon nanotubes on a nonconductive PMMA substrate, where single-wall carbon nanotubes act as exclusive transducers. The coupling of ME–SW-PTEs allowed the fast detection of MT, Trp, and 5-HT in less than 150 s with excellent analytical features. It exhibited an impressive antifouling performance with RSD values of ≤2 and ≤4% for migration times and peak heights, respectively (n = 12). In addition, sample analysis was also investigated by analysis of 5-HT, MT, and Trp in commercial samples obtaining excellent quantitative and reproducible recoveries with values of 96.2 ± 1.8%, 101.3 ± 0.2%, and 95.6 ± 1.2% for 5-HT, MT, and Trp, respectively. The current novel application reveals the analytical power of the press-transfer technology where the fast and reliable determination of MT and its precursors were performed directly on the nanoscale carbon nanotube detectors without the help of any other electrochemical transducer.Fil: Gomez, Federico Jose Vicente. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; ArgentinaFil: Martin, Aida. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; EspañaFil: Silva, María Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; ArgentinaFil: Escarpa, Alberto. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; EspañaWiley VCH Verlag2015-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/22875Gomez, Federico Jose Vicente; Martin, Aida; Silva, María Fernanda; Escarpa, Alberto; Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors; Wiley VCH Verlag; Electrophoresis; 36; 16; 5-2015; 1880-18850173-0835CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/elps.201400580/abstractinfo:eu-repo/semantics/altIdentifier/doi/10.1002/elps.201400580info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:09:22Zoai:ri.conicet.gov.ar:11336/22875instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:09:22.999CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
title Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
spellingShingle Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
Gomez, Federico Jose Vicente
Carbon Nanotubes
Melatonin
Press-Transferred Electrodes
title_short Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
title_full Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
title_fullStr Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
title_full_unstemmed Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
title_sort Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors
dc.creator.none.fl_str_mv Gomez, Federico Jose Vicente
Martin, Aida
Silva, María Fernanda
Escarpa, Alberto
author Gomez, Federico Jose Vicente
author_facet Gomez, Federico Jose Vicente
Martin, Aida
Silva, María Fernanda
Escarpa, Alberto
author_role author
author2 Martin, Aida
Silva, María Fernanda
Escarpa, Alberto
author2_role author
author
author
dc.subject.none.fl_str_mv Carbon Nanotubes
Melatonin
Press-Transferred Electrodes
topic Carbon Nanotubes
Melatonin
Press-Transferred Electrodes
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the current work, single-wall carbon nanotube press-transferred electrodes (SW-PTEs) were used for detection of melatonin (MT) and its precursors tryptophan (Trp) and serotonin (5-HT) on microchip electrophoresis (ME). SW-PTEs were simply fabricated by press transferring a filtered dispersion of single-wall carbon nanotubes on a nonconductive PMMA substrate, where single-wall carbon nanotubes act as exclusive transducers. The coupling of ME–SW-PTEs allowed the fast detection of MT, Trp, and 5-HT in less than 150 s with excellent analytical features. It exhibited an impressive antifouling performance with RSD values of ≤2 and ≤4% for migration times and peak heights, respectively (n = 12). In addition, sample analysis was also investigated by analysis of 5-HT, MT, and Trp in commercial samples obtaining excellent quantitative and reproducible recoveries with values of 96.2 ± 1.8%, 101.3 ± 0.2%, and 95.6 ± 1.2% for 5-HT, MT, and Trp, respectively. The current novel application reveals the analytical power of the press-transfer technology where the fast and reliable determination of MT and its precursors were performed directly on the nanoscale carbon nanotube detectors without the help of any other electrochemical transducer.
Fil: Gomez, Federico Jose Vicente. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; Argentina
Fil: Martin, Aida. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España
Fil: Silva, María Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Biología Agrícola de Mendoza. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Instituto de Biología Agrícola de Mendoza; Argentina
Fil: Escarpa, Alberto. Universidad de Alcalá. Departamento de Química Analítica, Química física e Ingeniería Química; España
description In the current work, single-wall carbon nanotube press-transferred electrodes (SW-PTEs) were used for detection of melatonin (MT) and its precursors tryptophan (Trp) and serotonin (5-HT) on microchip electrophoresis (ME). SW-PTEs were simply fabricated by press transferring a filtered dispersion of single-wall carbon nanotubes on a nonconductive PMMA substrate, where single-wall carbon nanotubes act as exclusive transducers. The coupling of ME–SW-PTEs allowed the fast detection of MT, Trp, and 5-HT in less than 150 s with excellent analytical features. It exhibited an impressive antifouling performance with RSD values of ≤2 and ≤4% for migration times and peak heights, respectively (n = 12). In addition, sample analysis was also investigated by analysis of 5-HT, MT, and Trp in commercial samples obtaining excellent quantitative and reproducible recoveries with values of 96.2 ± 1.8%, 101.3 ± 0.2%, and 95.6 ± 1.2% for 5-HT, MT, and Trp, respectively. The current novel application reveals the analytical power of the press-transfer technology where the fast and reliable determination of MT and its precursors were performed directly on the nanoscale carbon nanotube detectors without the help of any other electrochemical transducer.
publishDate 2015
dc.date.none.fl_str_mv 2015-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/22875
Gomez, Federico Jose Vicente; Martin, Aida; Silva, María Fernanda; Escarpa, Alberto; Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors; Wiley VCH Verlag; Electrophoresis; 36; 16; 5-2015; 1880-1885
0173-0835
CONICET Digital
CONICET
url http://hdl.handle.net/11336/22875
identifier_str_mv Gomez, Federico Jose Vicente; Martin, Aida; Silva, María Fernanda; Escarpa, Alberto; Microchip electrophoresis-single wall carbon nanotube press-transferred electrodes for fast and reliable electrochemical sensing of melatonin and its precursors; Wiley VCH Verlag; Electrophoresis; 36; 16; 5-2015; 1880-1885
0173-0835
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/elps.201400580/abstract
info:eu-repo/semantics/altIdentifier/doi/10.1002/elps.201400580
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley VCH Verlag
publisher.none.fl_str_mv Wiley VCH Verlag
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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