Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach

Autores
Heisecke Peralta, Silvina Lidia; Campaña, Hebe; Santos, María Rita; López Camelo, Jorge Santiago; Rittler, Monica
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Interbirth interval (IBI), the time between consecutive births, has been tied to perinatal outcomes.Objective: To analyze adverse perinatal events following short IBI in a large South American sample.Study design: Observational, retrospective, hospital-based study including malformed and nonmalformed live- and stillbirths. Outcomes were preterm birth (PTB), low birth weight (LBW), and specific birth defects. Logistic regressions were used to evaluate the risk of selected variables for short IBI and for adverse outcomes after short IBI, adjusting by confounders. Bayesian networks exhibited relationships among short IBI, outcomes, and variables.Results: Short IBI rate was 2%-3%. Maternal age and a previous abortion were the main confounders. A significant high risk for short IBI was found in mothers ≤19 years while mothers ≥30 were at low risk, mediated by a previous abortion. The risk of short IBI, adjusted by confounders, was significant for LBW but not for PTB. An unadjusted risk of short IBI was observed for gastroschisis, which disappeared after adjusting for confounders. Maternal age ≤19 and previous abortion were directly related with gastroschisis; the relationship between gastroschisis and short IBI occurred through any of these two variables. A direct relationship between gastroschisis and maternal age ≥30 was observed.Conclusions: Only young mothers were directly related with short IBI. In older mothers, a short IBI mainly occurred after a previous abortion. Short IBI was a risk factor only for LBW. The PTB and gastroschisis relationship with short IBI was indirect, mediated by young maternal age and/or a previous abortion.
Fil: Heisecke Peralta, Silvina Lidia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Campaña, Hebe. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Santos, María Rita. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: López Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Rittler, Monica. Hospital Materno Infantil Ramon Sarda ; Gobierno de la Ciudad Autonoma de Buenos Aires;
Materia
gastroschisis;
interbirth interval;
low birth weight;
maternal age;
previous abortion
gastroschisis;
interbirth interval;
low birth weight;
maternal age;
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/272961
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/272961
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approachHeisecke Peralta, Silvina LidiaCampaña, HebeSantos, María RitaLópez Camelo, Jorge SantiagoRittler, Monicagastroschisis;interbirth interval;low birth weight;maternal age;previous abortiongastroschisis;interbirth interval;low birth weight;maternal age;https://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: Interbirth interval (IBI), the time between consecutive births, has been tied to perinatal outcomes.Objective: To analyze adverse perinatal events following short IBI in a large South American sample.Study design: Observational, retrospective, hospital-based study including malformed and nonmalformed live- and stillbirths. Outcomes were preterm birth (PTB), low birth weight (LBW), and specific birth defects. Logistic regressions were used to evaluate the risk of selected variables for short IBI and for adverse outcomes after short IBI, adjusting by confounders. Bayesian networks exhibited relationships among short IBI, outcomes, and variables.Results: Short IBI rate was 2%-3%. Maternal age and a previous abortion were the main confounders. A significant high risk for short IBI was found in mothers ≤19 years while mothers ≥30 were at low risk, mediated by a previous abortion. The risk of short IBI, adjusted by confounders, was significant for LBW but not for PTB. An unadjusted risk of short IBI was observed for gastroschisis, which disappeared after adjusting for confounders. Maternal age ≤19 and previous abortion were directly related with gastroschisis; the relationship between gastroschisis and short IBI occurred through any of these two variables. A direct relationship between gastroschisis and maternal age ≥30 was observed.Conclusions: Only young mothers were directly related with short IBI. In older mothers, a short IBI mainly occurred after a previous abortion. Short IBI was a risk factor only for LBW. The PTB and gastroschisis relationship with short IBI was indirect, mediated by young maternal age and/or a previous abortion.Fil: Heisecke Peralta, Silvina Lidia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Campaña, Hebe. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Santos, María Rita. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: López Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; ArgentinaFil: Rittler, Monica. Hospital Materno Infantil Ramon Sarda ; Gobierno de la Ciudad Autonoma de Buenos Aires;Elsevier2024-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/272961Heisecke Peralta, Silvina Lidia; Campaña, Hebe; Santos, María Rita; López Camelo, Jorge Santiago; Rittler, Monica; Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach; Elsevier; AJOG Global Reports; 4; 4; 11-2024; 1-82666-5778CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S266657782400100Xinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.xagr.2024.100406info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:08:16Zoai:ri.conicet.gov.ar:11336/272961instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:08:16.798CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
title Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
spellingShingle Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
Heisecke Peralta, Silvina Lidia
gastroschisis;
interbirth interval;
low birth weight;
maternal age;
previous abortion
gastroschisis;
interbirth interval;
low birth weight;
maternal age;
title_short Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
title_full Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
title_fullStr Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
title_full_unstemmed Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
title_sort Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach
dc.creator.none.fl_str_mv Heisecke Peralta, Silvina Lidia
Campaña, Hebe
Santos, María Rita
López Camelo, Jorge Santiago
Rittler, Monica
author Heisecke Peralta, Silvina Lidia
author_facet Heisecke Peralta, Silvina Lidia
Campaña, Hebe
Santos, María Rita
López Camelo, Jorge Santiago
Rittler, Monica
author_role author
author2 Campaña, Hebe
Santos, María Rita
López Camelo, Jorge Santiago
Rittler, Monica
author2_role author
author
author
author
dc.subject.none.fl_str_mv gastroschisis;
interbirth interval;
low birth weight;
maternal age;
previous abortion
gastroschisis;
interbirth interval;
low birth weight;
maternal age;
topic gastroschisis;
interbirth interval;
low birth weight;
maternal age;
previous abortion
gastroschisis;
interbirth interval;
low birth weight;
maternal age;
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Interbirth interval (IBI), the time between consecutive births, has been tied to perinatal outcomes.Objective: To analyze adverse perinatal events following short IBI in a large South American sample.Study design: Observational, retrospective, hospital-based study including malformed and nonmalformed live- and stillbirths. Outcomes were preterm birth (PTB), low birth weight (LBW), and specific birth defects. Logistic regressions were used to evaluate the risk of selected variables for short IBI and for adverse outcomes after short IBI, adjusting by confounders. Bayesian networks exhibited relationships among short IBI, outcomes, and variables.Results: Short IBI rate was 2%-3%. Maternal age and a previous abortion were the main confounders. A significant high risk for short IBI was found in mothers ≤19 years while mothers ≥30 were at low risk, mediated by a previous abortion. The risk of short IBI, adjusted by confounders, was significant for LBW but not for PTB. An unadjusted risk of short IBI was observed for gastroschisis, which disappeared after adjusting for confounders. Maternal age ≤19 and previous abortion were directly related with gastroschisis; the relationship between gastroschisis and short IBI occurred through any of these two variables. A direct relationship between gastroschisis and maternal age ≥30 was observed.Conclusions: Only young mothers were directly related with short IBI. In older mothers, a short IBI mainly occurred after a previous abortion. Short IBI was a risk factor only for LBW. The PTB and gastroschisis relationship with short IBI was indirect, mediated by young maternal age and/or a previous abortion.
Fil: Heisecke Peralta, Silvina Lidia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Campaña, Hebe. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Santos, María Rita. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: López Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
Fil: Rittler, Monica. Hospital Materno Infantil Ramon Sarda ; Gobierno de la Ciudad Autonoma de Buenos Aires;
description Background: Interbirth interval (IBI), the time between consecutive births, has been tied to perinatal outcomes.Objective: To analyze adverse perinatal events following short IBI in a large South American sample.Study design: Observational, retrospective, hospital-based study including malformed and nonmalformed live- and stillbirths. Outcomes were preterm birth (PTB), low birth weight (LBW), and specific birth defects. Logistic regressions were used to evaluate the risk of selected variables for short IBI and for adverse outcomes after short IBI, adjusting by confounders. Bayesian networks exhibited relationships among short IBI, outcomes, and variables.Results: Short IBI rate was 2%-3%. Maternal age and a previous abortion were the main confounders. A significant high risk for short IBI was found in mothers ≤19 years while mothers ≥30 were at low risk, mediated by a previous abortion. The risk of short IBI, adjusted by confounders, was significant for LBW but not for PTB. An unadjusted risk of short IBI was observed for gastroschisis, which disappeared after adjusting for confounders. Maternal age ≤19 and previous abortion were directly related with gastroschisis; the relationship between gastroschisis and short IBI occurred through any of these two variables. A direct relationship between gastroschisis and maternal age ≥30 was observed.Conclusions: Only young mothers were directly related with short IBI. In older mothers, a short IBI mainly occurred after a previous abortion. Short IBI was a risk factor only for LBW. The PTB and gastroschisis relationship with short IBI was indirect, mediated by young maternal age and/or a previous abortion.
publishDate 2024
dc.date.none.fl_str_mv 2024-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/272961
Heisecke Peralta, Silvina Lidia; Campaña, Hebe; Santos, María Rita; López Camelo, Jorge Santiago; Rittler, Monica; Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach; Elsevier; AJOG Global Reports; 4; 4; 11-2024; 1-8
2666-5778
CONICET Digital
CONICET
url http://hdl.handle.net/11336/272961
identifier_str_mv Heisecke Peralta, Silvina Lidia; Campaña, Hebe; Santos, María Rita; López Camelo, Jorge Santiago; Rittler, Monica; Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach; Elsevier; AJOG Global Reports; 4; 4; 11-2024; 1-8
2666-5778
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S266657782400100X
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.xagr.2024.100406
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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