Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose

Autores
Rodriguez-Tudela, Juan Luis; Gomez-Lopez, Alicia; Arendrup, Maiken C.; Garcia, Guillermo Manuel; Perlin, David S.; Lass-Flörl, Cornelia; Cuenca-Estrella, Manuel
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
According to the product insert for Cancidas (caspofungin acetate), the drug must not be diluted in solutions containing glucose as this decreases caspofungin stability. The aim of this study was to compare caspofungin MICs for a collection of yeasts by means of EUCAST method EDef7.1 but using two different concentrations of glucose: 2% versus 0.2%. MICs were identical or within one 2-fold dilution for 93 out of 95 strains (97.9%), showing that glucose does not interfere with susceptibility.
Fil: Rodriguez-Tudela, Juan Luis. Centro Nacional de Microbiología; España
Fil: Gomez-Lopez, Alicia. Centro Nacional de Microbiología; España
Fil: Arendrup, Maiken C.. Statens Serum Institut;
Fil: Garcia, Guillermo Manuel. Universidad Nacional del Litoral; Argentina
Fil: Perlin, David S.. Public Health Research Institute; Estados Unidos
Fil: Lass-Flörl, Cornelia. Medizinische Universitat Innsbruck; Austria
Fil: Cuenca-Estrella, Manuel. Centro Nacional de Microbiología; España
Materia
Echinocandinas
Resistencia
Evaluación sensibilidad
Caspofungina
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/97694
Acceder
id CONICETDig_84fae13541e0979a2c0fab4727264529
oai_identifier_str oai:ri.conicet.gov.ar:11336/97694
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucoseRodriguez-Tudela, Juan LuisGomez-Lopez, AliciaArendrup, Maiken C.Garcia, Guillermo ManuelPerlin, David S.Lass-Flörl, CorneliaCuenca-Estrella, ManuelEchinocandinasResistenciaEvaluación sensibilidadCaspofunginahttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3According to the product insert for Cancidas (caspofungin acetate), the drug must not be diluted in solutions containing glucose as this decreases caspofungin stability. The aim of this study was to compare caspofungin MICs for a collection of yeasts by means of EUCAST method EDef7.1 but using two different concentrations of glucose: 2% versus 0.2%. MICs were identical or within one 2-fold dilution for 93 out of 95 strains (97.9%), showing that glucose does not interfere with susceptibility.Fil: Rodriguez-Tudela, Juan Luis. Centro Nacional de Microbiología; EspañaFil: Gomez-Lopez, Alicia. Centro Nacional de Microbiología; EspañaFil: Arendrup, Maiken C.. Statens Serum Institut; Fil: Garcia, Guillermo Manuel. Universidad Nacional del Litoral; ArgentinaFil: Perlin, David S.. Public Health Research Institute; Estados UnidosFil: Lass-Flörl, Cornelia. Medizinische Universitat Innsbruck; AustriaFil: Cuenca-Estrella, Manuel. Centro Nacional de Microbiología; EspañaAmerican Society for Microbiology2010-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/97694Rodriguez-Tudela, Juan Luis; Gomez-Lopez, Alicia; Arendrup, Maiken C.; Garcia, Guillermo Manuel; Perlin, David S.; et al.; Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 54; 7; 7-2010; 3056-30570066-4804CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1128/AAC.00597-10info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:26:00Zoai:ri.conicet.gov.ar:11336/97694instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:26:00.704CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
title Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
spellingShingle Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
Rodriguez-Tudela, Juan Luis
Echinocandinas
Resistencia
Evaluación sensibilidad
Caspofungina
title_short Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
title_full Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
title_fullStr Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
title_full_unstemmed Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
title_sort Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose
dc.creator.none.fl_str_mv Rodriguez-Tudela, Juan Luis
Gomez-Lopez, Alicia
Arendrup, Maiken C.
Garcia, Guillermo Manuel
Perlin, David S.
Lass-Flörl, Cornelia
Cuenca-Estrella, Manuel
author Rodriguez-Tudela, Juan Luis
author_facet Rodriguez-Tudela, Juan Luis
Gomez-Lopez, Alicia
Arendrup, Maiken C.
Garcia, Guillermo Manuel
Perlin, David S.
Lass-Flörl, Cornelia
Cuenca-Estrella, Manuel
author_role author
author2 Gomez-Lopez, Alicia
Arendrup, Maiken C.
Garcia, Guillermo Manuel
Perlin, David S.
Lass-Flörl, Cornelia
Cuenca-Estrella, Manuel
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Echinocandinas
Resistencia
Evaluación sensibilidad
Caspofungina
topic Echinocandinas
Resistencia
Evaluación sensibilidad
Caspofungina
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv According to the product insert for Cancidas (caspofungin acetate), the drug must not be diluted in solutions containing glucose as this decreases caspofungin stability. The aim of this study was to compare caspofungin MICs for a collection of yeasts by means of EUCAST method EDef7.1 but using two different concentrations of glucose: 2% versus 0.2%. MICs were identical or within one 2-fold dilution for 93 out of 95 strains (97.9%), showing that glucose does not interfere with susceptibility.
Fil: Rodriguez-Tudela, Juan Luis. Centro Nacional de Microbiología; España
Fil: Gomez-Lopez, Alicia. Centro Nacional de Microbiología; España
Fil: Arendrup, Maiken C.. Statens Serum Institut;
Fil: Garcia, Guillermo Manuel. Universidad Nacional del Litoral; Argentina
Fil: Perlin, David S.. Public Health Research Institute; Estados Unidos
Fil: Lass-Flörl, Cornelia. Medizinische Universitat Innsbruck; Austria
Fil: Cuenca-Estrella, Manuel. Centro Nacional de Microbiología; España
description According to the product insert for Cancidas (caspofungin acetate), the drug must not be diluted in solutions containing glucose as this decreases caspofungin stability. The aim of this study was to compare caspofungin MICs for a collection of yeasts by means of EUCAST method EDef7.1 but using two different concentrations of glucose: 2% versus 0.2%. MICs were identical or within one 2-fold dilution for 93 out of 95 strains (97.9%), showing that glucose does not interfere with susceptibility.
publishDate 2010
dc.date.none.fl_str_mv 2010-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/97694
Rodriguez-Tudela, Juan Luis; Gomez-Lopez, Alicia; Arendrup, Maiken C.; Garcia, Guillermo Manuel; Perlin, David S.; et al.; Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 54; 7; 7-2010; 3056-3057
0066-4804
CONICET Digital
CONICET
url http://hdl.handle.net/11336/97694
identifier_str_mv Rodriguez-Tudela, Juan Luis; Gomez-Lopez, Alicia; Arendrup, Maiken C.; Garcia, Guillermo Manuel; Perlin, David S.; et al.; Comparison of caspofungin MICs by means of EUCAST method EDef 7.1 using two different concentrations of glucose; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 54; 7; 7-2010; 3056-3057
0066-4804
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1128/AAC.00597-10
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781814725672960
score 12.982451

Publicaciones similares