Antimicrobial consumption at the hospital level in latin america. Similarities and differences according to each country

• Autores: Marin, Gustavo Horacio; Giangreco, Luis; Hernández, Yago; Dorati, Cristian; Mordujovich Buschiazzo, Perla; Bay, María Rosa; Gonzalez, Gladys María Adriana; Aldunate, Francisca; López Peña, Mónica; Martínez Parra, Adriana; Ching Fung, Shing Mi; Alfonso Arvez, María José; Mantilla Ponte, Hilda; Marin, Danini; Rojas, Robin; Castro, José Luis
• Año de publicación: 2023
• Idioma: inglés
• Tipo de recurso: artículo
• Materia: antimicrobial; AWaRe; Consumption
• Institución: Consejo Nacional de Investigaciones Científicas y Técnicas

One of the main problems for health service around the world is the antimicrobial resistance (AMR). Objective: to describe the antimicrobial consumption (AMC) at hospital level in Latin American countries and compare the amount and type of antibiotics usage among them in order to guide local public health actions towards AMR prevention.Design: A descriptive study of antimicrobial consumption at hospital level among six health institution in Latin America with an analytical comparative stage. Antimicrobials included corresponded to the WHO Anatomical Therapeutic Chemical (ATC) classification system subgroups: J01, A07A and P01AB. Methods: WHO GLASS methodology was applied for surveillance of AMC, using the ATC classification based on Defined Daily Dose (DDD) and DDD/100 hospital discharges as standard unit of measurement. Antimicrobials consumed were also classified according to the WHO AccessWatch-Reserve (AWaRe) classification. Results: The quantitative data, measured in DDD/100 hospital discharges, showed a wide range of consumption (182.48 - 2260.95). Qualitative analysis according to the AWaRe classification also showed a wide range in terms of consumption of Access (38.14% - 73.64%), Watch (24.93% - 60 .53%) and Reserve (0.31% - 3.55%) groups expressed as a percentage of the total consumption.Conclusion: Great heterogeneity and arbitrariness exist in the selection of antimicrobials for hospital use. Although this situation might be explained on local antimicrobial resistance, the history of prescription, local pharmaceutical promotion, and pharmacological education of health professional in each country, particular habits and distinctive culture may justify the differential consumption patterns observed in each institution in this study.
Fil: Marin, Gustavo Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata; Argentina
Fil: Giangreco, Luis. Universidad Nacional de La Plata; Argentina
Fil: Hernández, Yago. Universidad Nacional de La Plata; Argentina
Fil: Dorati, Cristian. Universidad Nacional de La Plata; Argentina
Fil: Mordujovich Buschiazzo, Perla. Universidad Nacional de La Plata; Argentina
Fil: Bay, María Rosa. Hospital Interzonal General de Agudos San Roque - Mb Gonnet ; Gobierno de la Provincia de Buenos Aires;
Fil: Gonzalez, Gladys María Adriana. Hospital Interzonal General de Agudos San Roque - Mb Gonnet ; Gobierno de la Provincia de Buenos Aires;
Fil: Aldunate, Francisca. Pontificia Universidad Católica de Chile; Chile
Fil: López Peña, Mónica. Ministerio de Salud y Protección Social; Colombia
Fil: Martínez Parra, Adriana. Ministerio de Salud y Protección Social; Colombia
Fil: Ching Fung, Shing Mi. Costa Rican social security; Costa Rica
Fil: Alfonso Arvez, María José. Ministry of Public Health and Social Welfare; Paraguay
Fil: Mantilla Ponte, Hilda. General Directorate of Medicines, Supplies and Drugs; Perú
Fil: Marin, Danini. General Directorate of Medicines, Supplies and Drugs; Perú
Fil: Rojas, Robin. General Directorate of Medicines, Supplies and Drugs; Perú
Fil: Castro, José Luis. Pan-American Health Organization; Estados Unidos