Cancer immunotherapy: Importance of overcoming immune suppression

Autores
Malvicini, Mariana; Puchulo, Guillermo; Matar, Pablo; Mazzolini Rizzo, Guillermo Daniel
Año de publicación
2010
Idioma
español castellano
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Increasing evidence indicates that the immune system is involved in the control of tumor progression. Effective antitumor immune response depends on the interaction between several components of the immune system, including antigen-presenting cells and different T cell subsets. However, tumor cells develop a number of mechanisms to escape recognition and elimination by the immune system. In this review we discuss these mechanisms and address possible therapeutic approaches to overcome the immune suppression generated by tumors.
Fil: Malvicini, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Laboratorio de Terapia Génica; Argentina
Fil: Puchulo, Guillermo. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina
Fil: Matar, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Medicas. Instituto de Genética Experimental; Argentina
Fil: Mazzolini Rizzo, Guillermo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Laboratorio de Terapia Génica; Argentina
Materia
Cancer
Immunotherapy
Immunosuppression
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/188936
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Cancer immunotherapy: Importance of overcoming immune suppressionInmunoterapia del cáncer: Importancia de controlar la inmunosupresiónMalvicini, MarianaPuchulo, GuillermoMatar, PabloMazzolini Rizzo, Guillermo DanielCancerImmunotherapyImmunosuppressionhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Increasing evidence indicates that the immune system is involved in the control of tumor progression. Effective antitumor immune response depends on the interaction between several components of the immune system, including antigen-presenting cells and different T cell subsets. However, tumor cells develop a number of mechanisms to escape recognition and elimination by the immune system. In this review we discuss these mechanisms and address possible therapeutic approaches to overcome the immune suppression generated by tumors.Fil: Malvicini, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Laboratorio de Terapia Génica; ArgentinaFil: Puchulo, Guillermo. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; ArgentinaFil: Matar, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Medicas. Instituto de Genética Experimental; ArgentinaFil: Mazzolini Rizzo, Guillermo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Laboratorio de Terapia Génica; ArgentinaMedicina (Buenos Aires)2010-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/188936Malvicini, Mariana; Puchulo, Guillermo; Matar, Pablo; Mazzolini Rizzo, Guillermo Daniel; Cancer immunotherapy: Importance of overcoming immune suppression; Medicina (Buenos Aires); Medicina (Buenos Aires); 70; 6; 6-2010; 565-5700025-76801669-9106CONICET DigitalCONICETspainfo:eu-repo/semantics/altIdentifier/url/https://www.medicinabuenosaires.com/demo/revistas/vol70-10/6/indice.pdfinfo:eu-repo/semantics/altIdentifier/url/http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802010000600016&lng=es&nrm=iso&tlng=esinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:42:35Zoai:ri.conicet.gov.ar:11336/188936instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:42:35.678CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cancer immunotherapy: Importance of overcoming immune suppression
Inmunoterapia del cáncer: Importancia de controlar la inmunosupresión
title Cancer immunotherapy: Importance of overcoming immune suppression
spellingShingle Cancer immunotherapy: Importance of overcoming immune suppression
Malvicini, Mariana
Cancer
Immunotherapy
Immunosuppression
title_short Cancer immunotherapy: Importance of overcoming immune suppression
title_full Cancer immunotherapy: Importance of overcoming immune suppression
title_fullStr Cancer immunotherapy: Importance of overcoming immune suppression
title_full_unstemmed Cancer immunotherapy: Importance of overcoming immune suppression
title_sort Cancer immunotherapy: Importance of overcoming immune suppression
dc.creator.none.fl_str_mv Malvicini, Mariana
Puchulo, Guillermo
Matar, Pablo
Mazzolini Rizzo, Guillermo Daniel
author Malvicini, Mariana
author_facet Malvicini, Mariana
Puchulo, Guillermo
Matar, Pablo
Mazzolini Rizzo, Guillermo Daniel
author_role author
author2 Puchulo, Guillermo
Matar, Pablo
Mazzolini Rizzo, Guillermo Daniel
author2_role author
author
author
dc.subject.none.fl_str_mv Cancer
Immunotherapy
Immunosuppression
topic Cancer
Immunotherapy
Immunosuppression
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Increasing evidence indicates that the immune system is involved in the control of tumor progression. Effective antitumor immune response depends on the interaction between several components of the immune system, including antigen-presenting cells and different T cell subsets. However, tumor cells develop a number of mechanisms to escape recognition and elimination by the immune system. In this review we discuss these mechanisms and address possible therapeutic approaches to overcome the immune suppression generated by tumors.
Fil: Malvicini, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Laboratorio de Terapia Génica; Argentina
Fil: Puchulo, Guillermo. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina
Fil: Matar, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Medicas. Instituto de Genética Experimental; Argentina
Fil: Mazzolini Rizzo, Guillermo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Laboratorio de Investigaciones Biomédicas; Argentina. Laboratorio de Terapia Génica; Argentina
description Increasing evidence indicates that the immune system is involved in the control of tumor progression. Effective antitumor immune response depends on the interaction between several components of the immune system, including antigen-presenting cells and different T cell subsets. However, tumor cells develop a number of mechanisms to escape recognition and elimination by the immune system. In this review we discuss these mechanisms and address possible therapeutic approaches to overcome the immune suppression generated by tumors.
publishDate 2010
dc.date.none.fl_str_mv 2010-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/188936
Malvicini, Mariana; Puchulo, Guillermo; Matar, Pablo; Mazzolini Rizzo, Guillermo Daniel; Cancer immunotherapy: Importance of overcoming immune suppression; Medicina (Buenos Aires); Medicina (Buenos Aires); 70; 6; 6-2010; 565-570
0025-7680
1669-9106
CONICET Digital
CONICET
url http://hdl.handle.net/11336/188936
identifier_str_mv Malvicini, Mariana; Puchulo, Guillermo; Matar, Pablo; Mazzolini Rizzo, Guillermo Daniel; Cancer immunotherapy: Importance of overcoming immune suppression; Medicina (Buenos Aires); Medicina (Buenos Aires); 70; 6; 6-2010; 565-570
0025-7680
1669-9106
CONICET Digital
CONICET
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.medicinabuenosaires.com/demo/revistas/vol70-10/6/indice.pdf
info:eu-repo/semantics/altIdentifier/url/http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802010000600016&lng=es&nrm=iso&tlng=es
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Medicina (Buenos Aires)
publisher.none.fl_str_mv Medicina (Buenos Aires)
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.069144

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