Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina

Autores
Luna, Leandro Hernan; Aranda, Claudia Marcela; Santos, Ana Luisa; Ramundo, Paola Silvia; Rizzuti, Claudio; Stagno, Diego
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Prostate carcinoma is a common malignant neoplasia that mostly metastasizes to bone in males. Nonetheless, the number of paleopathological cases reported is very small. Most of them were identified in Europe, and only two came from South American individuals. The purpose of this paper is to document the lesions identified in a pre-Columbian (around 1400 AD) individual that corresponds to a middle adult male from Pukara de la Cueva, Jujuy province, in the Northwest region of Argentina. The skeleton was found disarticulated but it is nearly complete and well preserved. The general character of the lesions observed is predominantly proliferative in nature, but osteolytic and mixed patterns were also detected in both axial and appendicular skeleton. Macroscopically, this overall pattern and the distribution of the lesions are compatible with a secondary cancer. Radiological examination showed multiple dense and irregular areas in several bones. The lesions visible by external inspection and by radiographs are in concordance with changes which are documented to occur in the course of prostatic carcinoma. The exuberance and dissemination of the lesions all over the skeleton led infer individual cachexy implying that he would have been assisted by his family and/or social group during the chronic process. Different carcinogenic risk factors associated to this kind of disease are discussed. This analysis adds new evidence of pre- Columbian carcinoma in South American native populations, as knowledge from clinical cases is considered to delineate a differential diagnosis.
Fil: Luna, Leandro Hernan. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aranda, Claudia Marcela. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina
Fil: Santos, Ana Luisa. Universidad de Coimbra; Portugal
Fil: Ramundo, Paola Silvia. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rizzuti, Claudio. Sociedad Argentina de Radiología; Argentina
Fil: Stagno, Diego. Sociedad Argentina de Radiología; Argentina
Materia
Metastases
Osteolytic Lesions
Paleopathology
Proliferative Bone
Tumor
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/51805
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern ArgentinaLuna, Leandro HernanAranda, Claudia MarcelaSantos, Ana LuisaRamundo, Paola SilviaRizzuti, ClaudioStagno, DiegoMetastasesOsteolytic LesionsPaleopathologyProliferative BoneTumorhttps://purl.org/becyt/ford/6.1https://purl.org/becyt/ford/6Prostate carcinoma is a common malignant neoplasia that mostly metastasizes to bone in males. Nonetheless, the number of paleopathological cases reported is very small. Most of them were identified in Europe, and only two came from South American individuals. The purpose of this paper is to document the lesions identified in a pre-Columbian (around 1400 AD) individual that corresponds to a middle adult male from Pukara de la Cueva, Jujuy province, in the Northwest region of Argentina. The skeleton was found disarticulated but it is nearly complete and well preserved. The general character of the lesions observed is predominantly proliferative in nature, but osteolytic and mixed patterns were also detected in both axial and appendicular skeleton. Macroscopically, this overall pattern and the distribution of the lesions are compatible with a secondary cancer. Radiological examination showed multiple dense and irregular areas in several bones. The lesions visible by external inspection and by radiographs are in concordance with changes which are documented to occur in the course of prostatic carcinoma. The exuberance and dissemination of the lesions all over the skeleton led infer individual cachexy implying that he would have been assisted by his family and/or social group during the chronic process. Different carcinogenic risk factors associated to this kind of disease are discussed. This analysis adds new evidence of pre- Columbian carcinoma in South American native populations, as knowledge from clinical cases is considered to delineate a differential diagnosis.Fil: Luna, Leandro Hernan. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Aranda, Claudia Marcela. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; ArgentinaFil: Santos, Ana Luisa. Universidad de Coimbra; PortugalFil: Ramundo, Paola Silvia. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rizzuti, Claudio. Sociedad Argentina de Radiología; ArgentinaFil: Stagno, Diego. Sociedad Argentina de Radiología; ArgentinaE Schweizerbartsche Verlags2015-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/51805Luna, Leandro Hernan; Aranda, Claudia Marcela; Santos, Ana Luisa; Ramundo, Paola Silvia; Rizzuti, Claudio; et al.; Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina; E Schweizerbartsche Verlags; Anthropologischer Anzeiger; 72; 2; 4-2015; 201-2220003-5548CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1127/anthranz/2015/0463info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/content/schweiz/aa/2015/00000072/00000002/art00005info:eu-repo/semantics/altIdentifier/url/https://www.schweizerbart.de/papers/anthranz/detail/72/84827/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:03:03Zoai:ri.conicet.gov.ar:11336/51805instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:03:03.397CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
title Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
spellingShingle Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
Luna, Leandro Hernan
Metastases
Osteolytic Lesions
Paleopathology
Proliferative Bone
Tumor
title_short Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
title_full Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
title_fullStr Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
title_full_unstemmed Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
title_sort Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina
dc.creator.none.fl_str_mv Luna, Leandro Hernan
Aranda, Claudia Marcela
Santos, Ana Luisa
Ramundo, Paola Silvia
Rizzuti, Claudio
Stagno, Diego
author Luna, Leandro Hernan
author_facet Luna, Leandro Hernan
Aranda, Claudia Marcela
Santos, Ana Luisa
Ramundo, Paola Silvia
Rizzuti, Claudio
Stagno, Diego
author_role author
author2 Aranda, Claudia Marcela
Santos, Ana Luisa
Ramundo, Paola Silvia
Rizzuti, Claudio
Stagno, Diego
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Metastases
Osteolytic Lesions
Paleopathology
Proliferative Bone
Tumor
topic Metastases
Osteolytic Lesions
Paleopathology
Proliferative Bone
Tumor
purl_subject.fl_str_mv https://purl.org/becyt/ford/6.1
https://purl.org/becyt/ford/6
dc.description.none.fl_txt_mv Prostate carcinoma is a common malignant neoplasia that mostly metastasizes to bone in males. Nonetheless, the number of paleopathological cases reported is very small. Most of them were identified in Europe, and only two came from South American individuals. The purpose of this paper is to document the lesions identified in a pre-Columbian (around 1400 AD) individual that corresponds to a middle adult male from Pukara de la Cueva, Jujuy province, in the Northwest region of Argentina. The skeleton was found disarticulated but it is nearly complete and well preserved. The general character of the lesions observed is predominantly proliferative in nature, but osteolytic and mixed patterns were also detected in both axial and appendicular skeleton. Macroscopically, this overall pattern and the distribution of the lesions are compatible with a secondary cancer. Radiological examination showed multiple dense and irregular areas in several bones. The lesions visible by external inspection and by radiographs are in concordance with changes which are documented to occur in the course of prostatic carcinoma. The exuberance and dissemination of the lesions all over the skeleton led infer individual cachexy implying that he would have been assisted by his family and/or social group during the chronic process. Different carcinogenic risk factors associated to this kind of disease are discussed. This analysis adds new evidence of pre- Columbian carcinoma in South American native populations, as knowledge from clinical cases is considered to delineate a differential diagnosis.
Fil: Luna, Leandro Hernan. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Aranda, Claudia Marcela. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina
Fil: Santos, Ana Luisa. Universidad de Coimbra; Portugal
Fil: Ramundo, Paola Silvia. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Museo Etnográfico "Juan B. Ambrosetti"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rizzuti, Claudio. Sociedad Argentina de Radiología; Argentina
Fil: Stagno, Diego. Sociedad Argentina de Radiología; Argentina
description Prostate carcinoma is a common malignant neoplasia that mostly metastasizes to bone in males. Nonetheless, the number of paleopathological cases reported is very small. Most of them were identified in Europe, and only two came from South American individuals. The purpose of this paper is to document the lesions identified in a pre-Columbian (around 1400 AD) individual that corresponds to a middle adult male from Pukara de la Cueva, Jujuy province, in the Northwest region of Argentina. The skeleton was found disarticulated but it is nearly complete and well preserved. The general character of the lesions observed is predominantly proliferative in nature, but osteolytic and mixed patterns were also detected in both axial and appendicular skeleton. Macroscopically, this overall pattern and the distribution of the lesions are compatible with a secondary cancer. Radiological examination showed multiple dense and irregular areas in several bones. The lesions visible by external inspection and by radiographs are in concordance with changes which are documented to occur in the course of prostatic carcinoma. The exuberance and dissemination of the lesions all over the skeleton led infer individual cachexy implying that he would have been assisted by his family and/or social group during the chronic process. Different carcinogenic risk factors associated to this kind of disease are discussed. This analysis adds new evidence of pre- Columbian carcinoma in South American native populations, as knowledge from clinical cases is considered to delineate a differential diagnosis.
publishDate 2015
dc.date.none.fl_str_mv 2015-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/51805
Luna, Leandro Hernan; Aranda, Claudia Marcela; Santos, Ana Luisa; Ramundo, Paola Silvia; Rizzuti, Claudio; et al.; Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina; E Schweizerbartsche Verlags; Anthropologischer Anzeiger; 72; 2; 4-2015; 201-222
0003-5548
CONICET Digital
CONICET
url http://hdl.handle.net/11336/51805
identifier_str_mv Luna, Leandro Hernan; Aranda, Claudia Marcela; Santos, Ana Luisa; Ramundo, Paola Silvia; Rizzuti, Claudio; et al.; Probable prostate cancer in a pre-Incaic individual from Pukara de la Cueva, northwestern Argentina; E Schweizerbartsche Verlags; Anthropologischer Anzeiger; 72; 2; 4-2015; 201-222
0003-5548
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1127/anthranz/2015/0463
info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/content/schweiz/aa/2015/00000072/00000002/art00005
info:eu-repo/semantics/altIdentifier/url/https://www.schweizerbart.de/papers/anthranz/detail/72/84827/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv E Schweizerbartsche Verlags
publisher.none.fl_str_mv E Schweizerbartsche Verlags
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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